A new wideband electronically tunable grounded resistor employing only three MOS transistors

In this paper, a new wideband electronically tunable grounded resistor, namely a grounded voltage controlled resistor (GVCR) including only three MOS transistors, is suggested. The proposed GVCR, without requiring any additional bias currents and voltages, has only one control voltage. Linearity analysis for the proposed GVCR is given. A new second-order multifunctional filter using two differential voltage current conveyors is also included as an application example. Some postlayout simulation results with SPICE are included to show the performance, workability, and effectiveness. © 2016 Tübitak

A Navigation System for the Visually Impaired: A Fusion of Vision and Depth Sensor

For a number of years, scientists have been trying to develop aids that can make visually impaired people more independent and aware of their surroundings. Computer-based automatic navigation tools are one example of this, motivated by the increasing miniaturization of electronics and the improvement in processing power and sensing capabilities. This paper presents a complete navigation system based on low cost and physically unobtrusive sensors such as a camera and an infrared sensor. The system is based around corners and depth values from Kinect’s infrared sensor. Obstacles are found in images from a camera using corner detection, while input from the depth sensor provides the corresponding distance. The combination is both efficient and robust. The system not only identifies hurdles but also suggests a safe path (if available) to the left or right side and tells the user to stop, move left, or move right. The system has been tested in real time by both blindfolded and blind people at different indoor and outdoor locations, demonstrating that it operates adequately.</jats:p

How do supply chain management and information systems practices influence operational performance?:Evidence from emerging country SMEs

This study first provides a comparative analysis of the impact of supply chain management (SCM) and information systems (IS) practices on operational performance (OPER) of small- and medium-sized enterprises (SMEs) operating in two neighbouring emerging country markets of Turkey and Bulgaria. Then, we investigate moderating effects of both SCM–IS-linked enablers and inhibitors on the links between SCM and IS practices and OPER of SMEs. To this end, we first empirically identify the underlying dimensions of SCM and IS practices, and SCM–IS-related enabling and inhibiting factors. Second, a series of regression analyses are undertaken to estimate the impact of the study's constructs on OPER of SMEs. The results are discussed comparatively within the contexts of both Turkish and Bulgarian SMEs and beyond. The study makes a significant contribution to the extant literature through obtaining and analysing cross-national survey data of SCM and IS practices in emerging country markets

Assessment of the Awareness and Opinions of Turkish Medical Students Towards Violence Against Women: a Questionnaire-Based Study

DergiPark: 963037tmsjAims: This study aims to evaluate the opinions of medical students about violence against women, the education they receive during medical school regarding violence against women, and how they would manage a case of violence victims if they were to encounter it in their medical careers. Methods: In this question- naire-based study, 610 medical students from 37 medical schools were approached, and their opinions towards violence against women were evaluated through an online questionnaire. Demographic data such as age and gender were also gathered. Students were grouped according to their gender (male and female) and study levels; 1st, 2nd, and 3rd grades were grouped as pre-clinical, whereas students in 4th, 5th, and 6th grades were grouped as clinical. In comparing para- metric variables, the Student’s t-test was used, whereas, in non-parametric variables, the Mann-Whitney U test was used. The Chi-square test was used in the comparison of categorical variables. Results: There was a statistically significant difference within both groups (gender and study levels) for questions 5 (Which of the following would you describe as violence? [Multiple answers are allowed.]) and 13 (Do you think female physicians are exposed to violence more?). Our results also demonstrate a statistically significant difference for questions 15 (Is it obligatory for a physician to keep a legal report for a female patient who has been admitted to the emergency department as a victim of violence), 16 (It is not obligatory for a physician to keep a legal report for a female patient who has been admitted to the emergency department as a victim of violence without her consent.), and 17 (A physician is not obliged to complete the physical examina- tion or continue the diagnosis-treatment process of a female patient who has been a subject of violence without her consent.) between pre-clinical and clinical groups, where the clinical group gave the most correct answers. Conclusion: In conclusion, our results gave us a perspective that clinical students' awareness and management of violence against women is higher than pre-clinical students'. These results may be attributed to two factors; lectures on violence against women or the experience students attain during their clinical practices. Female students were keener in participating in our study. Further prospective studies with equal gender distribution investigating the possible impact of lectures about violence against women on physicians' management of similar situations are needed

Cantrell pentalojisi

Cantrel pentalojisi nadir görülen bir sendromdur. Gelişen teknoloji ile birlikte son yıllarda erken haftalarda tanı konabilmektedir. Tanı konulan hastalarda gebeliğin sonlandırılması önerilmekte ve bir çok hastada terminasyon uygulanmaktadır. Ancak nadiren de olsa aile terminasyon seçeneğini kabul etmediğinden dolayı terme ulaşan fetuslar görülmektedir. Bizim vakamız da terme kadar ulaşan ve doğum esnasında kaybedilen bir Cantrel pentalojisi vakasıdı

Effects of stock density on texture-colour quality and chemical composition of rainbow trout (Oncorhynchus mykiss)

This study describes the effects of different stocking densities on texture/colour characteristics, protein content/amino acid and lipid content/fatty acid composition of rainbow trout fillet. Stocking density was selected 5 (Group A), 15 (Group B), 25 (Group C) kg fish m^−3. Tukey’s Multiple Comparison Test showed insignificant differences between measured size/weight measurement and condition factors. No significant differences were found between A and C groups for colour analysis (L* and a* value) and texture profile analysis (hardness, adhesiveness, cohesiveness and gumminess values) of rainbow trout fillets. The proximate composition analysis showed rainbow trout fillets from the A and C groups to exhibit higher values of moisture than the B group. Fish from the A and B groups had a lower of ash and protein in comparison to C group samples. The highest fat values of rainbow trout were measured in B group samples. The content essential amino acid and non-essential amino acid was lower in A and B groups than in C groups. Fish from the C group had higher content of polyunsaturated fatty acids, especially n-3, docosahexanoic acid (DHA) and eicosapentaenoic acid (EPA) in comparison to A and C group. As a result, 25 kg fish m^−3 is recommended stock density in terms of product texture/color and composition quality

Papillary carcinoma arising in a thyroglossal duct cyst with associated microcarcinoma of the thyroid and without cervical lymph node metastasis: a case report

<p>Abstract</p> <p>Introduction</p> <p>This is a case report of a 44-year-old woman with papillary carcinoma of a thyroglossal duct cyst.</p> <p>Case presentation</p> <p>A 44 year-old woman presented to the otolaryngology outpatient clinic with an asymptomatic anterior midline neck mass. A cervical ultrasound showed a lesion which appeared to be a thyroglossal duct cyst and surgical resection using Sistrunk's procedure was performed. The histopathologic diagnosis showed papillary carcinoma evolving from a thyroglossal duct cyst, confined to the thyroglossal cyst, with a tumor diameter of 2 cm. The patient then underwent total thyroidectomy and bilateral neck dissection. The final pathology reported an 8 mm papillary cancer in the left lobe of the thyroid without any metastasis to the cervical lymph nodes. The patient was treated with radioactive iodide and thyroid suppresion therapy was given as adjuvant treatment. The patient has been following for two years without any metastasis.</p> <p>Conclusion</p> <p>Malignancy within a thyroglossal duct cyst is very rare but should be considered in the differential diagnosis of a midline neck mass.</p

StellaTUM: current consensus and discussion on pancreatic stellate cell research

The field of pancreatic stellate cell (PSC) biology is very young, as the essential in-vitro tools to study these cells (ie, methods to isolate and culture PSC) were only developed as recently as in 1998. Nonetheless, there has been an exponential increase in research output in this field over the past decade, with numerous research groups around the world focusing their energies into elucidating the biology and function of these cells. It is now well established that PSC are responsible for producing the stromal reaction (fibrosis) of two major diseases of the pancreas—chronic pancreatitis and pancreatic cancer. Despite exponentially increasing data, the methods for studying PSC remain variable. Although within individual laboratories methods are consistent, different methodologies used by various research groups make it difficult to compare results and conclusions. This article is not a review article on the functions of PSC. Instead, members of the Pancreatic Star Alliance (http://www.pancreaticstaralliance.com) discuss here and consolidate current knowledge, to outline and delineate areas of consensus or otherwise (eg, with regard to methodological approaches) and, more importantly, to identify essential directions for future research

βIII-tubulin: a novel mediator of chemoresistance and metastases in pancreatic cancer

Pancreatic cancer is a leading cause of cancer-related deaths in Western societies. This poor prognosis is due to chemotherapeutic drug resistance and metastatic spread. Evidence suggests that microtubule proteins namely, β-tubulins are dysregulated in tumor cells and are involved in regulating chemosensitivity. However, the role of β-tubulins in pancreatic cancer are unknown. We measured the expression of different β-tubulin isotypes in pancreatic adenocarcinoma tissue and pancreatic cancer cells. Next, we used RNAi to silence βIII-tubulin expression in pancreatic cancer cells, and measured cell growth in the absence and presence of chemotherapeutic drugs. Finally, we assessed the role of βIII-tubulin in regulating tumor growth and metastases using an orthotopic pancreatic cancer mouse model. We found that βIII-tubulin is highly expressed in pancreatic adenocarcinoma tissue and pancreatic cancer cells. Further, we demonstrated that silencing βIII-tubulin expression reduced pancreatic cancer cell growth and tumorigenic potential in the absence and presence of chemotherapeutic drugs. Finally, we demonstrated that suppression of βIII-tubulin reduced tumor growth and metastases in vivo. Our novel data demonstrate that βIII-tubulin is a key player in promoting pancreatic cancer growth and survival, and silencing its expression may be a potential therapeutic strategy to increase the long-term survival of pancreatic cancer patients