Threat Construction and Framing of Cyberterrorism in the U.S. News Media

This research aims to explore the influence of news media on the fear of cyberterrorism and how cyberterrorism is framed in the media. Using a mixed-method approach as a research strategy, this paper reports on two studies that explore the influence of news reading on the fear of cyberterrorism. The first study analyzed survey responses from 1,190 participants and found that increased exposure to reading news media was associated with increased fear of cyberterrorism. The second study, built on the first, sought to investigate how cyberterrorism is framed and constructed as a threat by the US local and national newspapers. The framing and portrayal of cyberterrorism in US newspapers are discussed

A Prevention and a Traction System for Ransomware Attacks

Over the past three years, especially following WannaCry malware, ransomware has become one of the biggest concerns for private businesses, state, and local government agencies. According to Homeland Security statistics, 1.5 million ransomware attacks have occurred per year since 2016. Cybercriminals often use creative methods to inject their malware into the target machines and use sophisticated cryptographic techniques to hold hostage victims' files and programs unless a certain amount of equivalent Bitcoin is paid. The return to the cybercriminals is so high (estimated \$1 billion in 2019) without any cost because of the advanced anonymity provided by cryptocurrencies, especially Bitcoin \cite{Paquet-Clouston2019}. Given this context, this study first discusses the current state of ransomware, detection, and prevention systems. Second, we propose a global ransomware center to better manage our concerted efforts against cybercriminals. The policy implications of the proposed study are discussed in the conclusion section

Strength of Hydrogen Bond Network Takes Crucial Roles in the Dissociation Process of Inhibitors from the HIV-1 Protease Binding Pocket

To understand the underlying mechanisms of significant differences in dissociation rate constant among different inhibitors for HIV-1 protease, we performed steered molecular dynamics (SMD) simulations to analyze the entire dissociation processes of inhibitors from the binding pocket of protease at atomistic details. We found that the strength of hydrogen bond network between inhibitor and the protease takes crucial roles in the dissociation process. We showed that the hydrogen bond network in the cyclic urea inhibitors AHA001/XK263 is less stable than that of the approved inhibitor ABT538 because of their large differences in the structures of the networks. In the cyclic urea inhibitor bound complex, the hydrogen bonds often distribute at the flap tips and the active site. In contrast, there are additional accessorial hydrogen bonds formed at the lateral sides of the flaps and the active site in the ABT538 bound complex, which take crucial roles in stabilizing the hydrogen bond network. In addition, the water molecule W301 also plays important roles in stabilizing the hydrogen bond network through its flexible movement by acting as a collision buffer and helping the rebinding of hydrogen bonds at the flap tips. Because of its high stability, the hydrogen bond network of ABT538 complex can work together with the hydrophobic clusters to resist the dissociation, resulting in much lower dissociation rate constant than those of cyclic urea inhibitor complexes. This study may provide useful guidelines for design of novel potent inhibitors with optimized interactions

Individual Disengagement and Deradicalization Pilot Program in Turkey: Methods and Outcomes

Counterterrorism strategies that mainly rely on hard power have long been used to defeat terrorism. In recent years, governments have begun incorporating soft power approaches not as a substitute, but as a complementary strategy to be applied alongside hard power approaches. Disengagement and deradicalization programs are important components of soft power approaches, and are regarded as significant contributors to traditional counterterrorism methods. In this paper, we analyze a locally developed counterterrorism program in Turkey, which resulted in the disengagement and deradicalization of hundreds of militants. In this paper we present an examination of a pilot program that focused on applying individual disengagement and deradicalization counterterrorism measures that was conducted by the Adana Police Department in Turkey between 2009 and 2015. This program was designed to reach out to the members of extremist groups and their families for the purpose of persuading them to disengage from their groups, change their radical mindsets, and help them reintegrate into society. We also discuss how the change in the government’s counterterrorism strategy from one which prioritizes the use of soft power approaches to another, which mostly utilizes the hard power approach, and almost completely discards the soft power method, influenced the implementation of the program

Trace elements in children suffering from idiopathic nephrotic syndrome.

OBJECTIVE: Trace elements play a significant role in several metabolic processes and often circulate in the blood binding to protein. The purpose of this study was to determine the status of selenium, zinc, and boron in idiopathic nephrotic syndrome patients in active and remission phases. MATERIALS AND METHODS: Fourteen patients and fourteen healthy age-matched controls were included in the study. The selenium, zinc and boron level in plasma and urine were measured by the inductively coupled plasma mass spectrometry. RESULTS: The plasma levels of zinc and selenium were significantly lower in both active and remission patients (for all p=0.0001). The plasma boron level was significantly lower only in patients in active phase (p=0.0002 vs control). The concentrations of urinary boron and selenium were significantly higher during active phase compared with remission (p=0.0003 and 0.0001, respectively). CONCLUSION: Supplementation with zinc, selenium and boron may be justified in patients suffering with this disease

Bone mineral density and bone metabolic markers' status in children with neurofibromatosis type 1.

AbstractBackground:Neurofibromatosis type 1 (NF1) is a multisystem disorder characterized by progressive manifestations, which is inherited in an autosomal dominant manner. The majority of patients with NF1 experience a diffuse, significant reduction in bone mass over time, with osteoporosis, osteopenia in the absence of severe scoliosis, or gross bone deformities. This study aimed to determine the bone mineral density (BMD) status, evaluate bone metabolism, and to determine the relevant factors in children with NF1.Methods:The study population included 33 pediatric NF1 patients (20 males and 13 females). Bone metabolic markers, such as total calcium, phosphorus, magnesium, alkaline phosphatase, parathyroid hormone, and 25-OH vitamin D, the urinary calcium/creatine ratio were measured. In addition, BMD was measured at both the lumbar spine (LS) and the femoral neck in all the patients.Results:All the patients had a low 25-OH vitamin D level, but it was significantly lower in the females than in the males (p&lt;0.009). Overall, 18.2% of the patients had skeletal abnormalities. The lumbar Z-score was ≤2 in 21.2% of the patients, whereas the femoral neck Z-score was ≤2 in 9.1%. The urinary calcium/creatine ratio was significantly higher in the female than in the male patients (p&lt;0.027). In all, six patients had skeletal abnormalities.Conclusions:It is widely known that bone mineral metabolism markers and BMD are significantly affected in NF1 patients; however, the present study did not identify any effective parameters that could be used to predict skeletal abnormalities, or diagnose early osteoporosis and osteopenia in pediatric NF1 patients.</jats:sec

Evaluation of geriatric infections in past six years

WOS: 000440345100505