Political Assessment of the October Revolution of 1917 as an Initial Stage in the Formation of the Personality Cult of Stalin in the Era of Proletarian Dictatorship

The question of the starting point of the ascent of I.V. Stalin to unified authority is still the key in the historiography of the October Revolution of 1917, which had a great influence on the formation of I.V. Stalin as a politician. The revolution has fostered in him a sense of purpose, a will to win, a desire not to overturn a political opponent. His role in the uprising is very modest. But from the speech to the speech on the pages of the Soviet mass media, Stalin more and more clearly emphasized his closeness to the leader of the revolution — V.I. Lenin, which was important for creating the image of one of the leaders of the armed uprising. Thus, the ascent to individual power began even before 1921, when Stalin became Secretary-General of the RCP (B)

The teacher's readiness to interact with gifted students

In the article, the authors consider the problem of a teacher's readiness to interact with gifted students in the process of their continuous development. In modern Russian society, there is a growing need for people who are extraordinarily thinking, creative, active, capable of solving tasks in an unconventional way and formulating new, promising goals. In these conditions, the support and development of gifted students undoubtedly become one of the priority tasks of the education system. The relevance of the work is due to the fact that the transition of general and vocational education to a new educational paradigm, caused by the transformations of Russian society, is accompanied by increased attention to gifted students, and as a result, by the preparation of teachers at all levels of the education system to interact with students, whose intellectual and creative potential is considered as state capital stock. The article presents the results of content analysis of scientific works in the field of the development of gifted students, as well as regulatory and legal acts of the Russian Federation in the field of education. The concept of pedagogical management is introduced (a set of approaches, principles, methods, organizational forms and technological and methodological teaching methods aimed at improving the quality and effectiveness of the continuous development of gifted students, which consists of the stages: identification, diagnosis, training, development, support and support ). As a result of the study, the authors, based on the principle of identifying the types of teacher's activities on the main stages of pedagogical management, proposed a component structure of the teacher's readiness to interact with gifted students, integrating motivational-value, cognitive-methodological, normative-organizational, reflexive-evaluative and communicative-tutoring component

Economic aspects of the cardiology program expansion of additional drugs provision by effective lipidlowering drugs for hypercholesterolemia control

The federal program of preferential drug provision in cardiology shows its effectiveness. However, hypercholesterolemia (HCH) remains a significant problem in patients in whom high-dose statin therapy does not provide the target level of low-density lipoprotein cholesterol (LDL cholesterol). The solution to the problem lies in the plane of prescribing lipid-lowering drugs of a different mechanism of action, for example, inhibitors of the PCSK9 enzyme. To recommend the inclusion of such kind drugs in the program, it is necessary not only to have evidence of their life-saving effect, but also the economic feasibility of their use. Aim: to evaluate the economic efficacy of alirocumab (INN) including in the federal program for patients who have suffered an acute coronary event, are receiving statins and have an LDL CH level of 5.0 mmol/l and higher.Materials and methods. Modeling was applied in a target group of 3029 patients of working age who had undergone ACS during the previous 12 months with severe, including familial, HCH, with LDL cholesterol 5.0 mmol/l and higher, receiving statins taking into account previously determined outcomes when using alirocumab + statins for 5 years. Direct medical and non-medical costs, as well as indirect costs, are identified. The cost-effectiveness analysis was applied from the point of view of the effectiveness of treatment (effects on mortality, temporary disability, disability) and direct health care costs (additional drug provision and outpatient follow-up, specialized, including high-tech, medical care in a 24‑hour hospital). Two healthcare technologies were compared: statin therapy and use of alirocumab + statins. The calculations used according to domestic methods used the cost of medical treatment, temporary disability, hospitalizations, loss of GDP and other parameters.Results. Modeling has shown a decrease in mortality, morbidity and disability when using alirocumab in even the first year of use. The economic effect of alirocumab from a decrease in temporary disability in the 1st year is 304.5 mln rub., in the 2nd — 301.5 mln rub., in the 3rd — 321.1 mln rub., in the 4th — 333.1 mln rub. The estimated amount of prevented GDP losses from mortality in the target group for 4 years in the case of alirocumab use amounted to 1,260.2 mln rub. The annual amount of avoidable GDP losses from mortality in the target group in the case of alirocumab is 27–30 %. The annual average savings per patient in the case of alirocumab use are from 7 to 17 %. The greatest impact on reducing losses from disability and mortality of the target group is noted in the group of people aged 40–59 years. Only for this group, if alirocumab is used, it is possible to reduce losses from disability and mortality by 159.2 million rubles per year (83 % of the total economic effect). Starting from the 4th year of alirocumab use, it is possible to obtain a positive economic effect in terms of hospitalization costs.Conclusion. When alirocumab is included in the program of additional drug provision in cardiology, the share of costs for the purchase of alirocumab for the target group may be only 0.01 %. At the same time, the economic effect of inclusion in the first year alone will amount to at least 393.4 million rubles of budget funds. The total amount of avoidable losses due to the alirocumab usage may amount to 1,638 million rubles over 4 years

Influence of desinchronizing effects of transmeridian flights on the circadian rhythm of sportsmen arterial pressure

Objective: to examine the characteristics and duration of phase-amplitude changes in circadian systolic rhythms (ADS) and diastolic blood pressure (ADD) in athletes in contrasting time regions on a east-west flight model in 7 time zones. Materials and methods: the registration of blood pressure was carried out at 07, 11, 15, 19, 23 hours of local time in «home» conditions and 28 days after the flights to the regions of the Moscow time zone. The methodology was based on a graphic representation of the material. Biorhythm graphs were imposed on the «home» periodogram in new temporal conditions, which made it possible to evaluate the phase-amplitude changes in the chronograms and find out when the patterns would repeat, i.e. adaptation of systemic blood pressure to geo-social changes in the environment. Results: it was shown that until the last 28th day of the study, the inverse deformation of the daily schedules of the BPA, BPA, a significant decrease in the BPA and pulse pressure (hypotensive effect), an increase in the BPA, an increase in the amplitude of fluctuations of the indicators remained. Conclusions: changes in the circadian rhythm of blood pressure in athletes in the regions with a 7-hour difference went beyond the month of research, indicating an incomplete adaptation of the hemodynamic system, which functioning was provided by a more costly, unprofitable for the body physiological mechanism that impairs the efficiency of the heart and at rest

Social and Psychological Features of Hardiness in Personality of Students of Higher Education Institutions

The topicality and significance of the study is determined by the fact that life and activity of a person in contemporary socio-economic conditions are inextricably connected with the constant impact of adverse social, political, economic and other factors on him. These factors are accompanied by the emergence of various kinds of difficult life situations, as a result of which stress develops in a person. In the student milieu, stress arises under the influence of difficulties associated with both the learning process and life circumstances. The paper presents the results of an empirical study of socio-psychological features of hardiness in students of higher educational institutions. The methods of research comprised: theoretical analysis, empirical research (testing), qualitative analysis of the obtained data, mathematical and statistical data processing (SPSS Statistics, Excel). Testing included the following psycho-diagnostic tools: the author’s questionnaire for assessing stressful situations; McCrae-Costa Five-Factor Personality Questionnaire (The Big Five dimensions); “Hardiness test”; Self-attitude technique. The validity and reliability of the study results was ensured by the initial methodological positions, the use of proven tools, sample representativeness of the research, as well as mathematical processing of data with the use of a software package for statistical analysis. As a result of the study, it was proved that emotion-focused ways of overcoming stress associated with a decrease in tension and a change in attitude to emerging difficulties prevail among the students of both the experimental and control groups. A high level of stress was found in the majority of subjects. In order to reduce this stress, it is necessary for students to form special skills to overcome it. In addition, an analysis of the psychological factors of students’ hardiness made it possible to determine the main areas of their psychological support in overcoming difficult life situations (development of qualities that form the core of students’ personal adaptive potential, the formation of their social competency, enrichment of social networks, as well as learning ways to find and accept social support)

Calculation of PandP_ and T_ odd effects in $"" sup 205_TIF including electron correlation

A method and codes for two-step correlation calculation of heavy-atom molecules have been developed, employing the generalized relativistic effective core potential and relativistic coupled cluster (RCC) methods at the first step, followed by nonvariational one-center restoration of proper four-component spinors in the heavy cores. Electron correlation is included for the first time in an ab initio calculation of the interaction of the permanent P,T-odd proton electric dipole moment with the internal electromagnetic field in a molecule. The calculation is performed for the ground state of TlF at the experimental equilibrium, R_e=2.0844 A, and at R=2.1 A, with spin-orbit and correlation effects included by RCC. Calculated results with single cluster amplitudes only are in good agreement (3% and 1%) with recent Dirac-Hartree-Fock (DHF) values of the magnetic parameter M; the larger differences occurring between present and DHF volume parameter (X) values, as well as between the two DHF calculations, are explained. Inclusion of electron correlation by GRECP/RCC with single and double excitations has a major effect on the P,T-odd parameters, decreasing M by 17% and X by 22%.Comment: 5 pages, REVTeX4 style Accepted for publication in Phys.Rev.Letter