Deep inelastic scattering structure functions of holographic spin-1 hadrons with Nf≥1N_f \geq 1

Two-point current correlation functions of the large $N$ limit of supersymmetric and non-supersymmetric Yang-Mills theories at strong coupling are investigated in terms of their string theory dual models with quenched flavors. We consider non-Abelian global symmetry currents, which allow one to investigate vector mesons with $N_f > 1$. From the correlation functions we construct the deep inelastic scattering hadronic tensor of spin-one mesons, obtaining the corresponding eight structure functions for polarized vector mesons. We obtain several relations among the structure functions. Relations among some of their moments are also derived. Aspects of the sub-leading contributions in the $1/N$ and $N_f/N$ expansions are discussed. At leading order we find a universal behavior of the hadronic structure functions.Comment: 48 pages, 8 figure

Deep inelastic scattering cross sections from the gauge/string duality

Differential cross sections of deep inelastic scattering of charged leptons from hadrons are investigated by using the gauge/string duality. We consider vector mesons derived from different holographic dual models obtaining a general expression. We focus on the strongly coupled regime of dual gauge theories for different values of the Bjorken parameter. We find new predictions which are particularly interesting for differential scattering cross sections of polarized leptons scattered off polarized vector mesons. We also carry out a detailed comparison of the moments of the structure functions with lattice QCD results.Comment: 42 pages, 5 tables, 9 figure

Design and synthesis of new molecules based on indolium derivatives for two-photon absorption bioimaging applications

Bioimaging is the visualization of biological processes in real time, interfering as less as possible with these and using non-invasive methods. Among others, fluorescence methods have acquired a very important role in these purposes through the nature of the light. Bioimaging pretends to understand how our organism works identifing subcellular organelles, following cellular processes, quantifying ion or biological species and visualising interactions of molecules with their targets in living cells or tissues. In the last decades, two-photon (TP) microscopy is unseating classical one-photon (OP) microscopy due to its advantages, such as the use of lower energy excitation wavelengths or the possibility of focus in depth, among others. Nowadays, it is an interesting target design and develop of new probes for TP microscopy to biomaging. Fluorophores based on indolenines are a family of compounds with promising properties in this sense. In this work, we present the design, synthesis and characterization of new indolium derivatives with promising properties to be used in bioimaging applications in living cells with different purposes.Real Sociedad Española de Química, Jóvenes Invetigadores Químicos, Facultad de Ciencias Ambientales y Bioquímica (UCLM), Merck, Cortes de Castilla la Mancha, Reaxys (Elsevier), Diputación de Toledo, MestreLab Research, Sección Territorial de Castilla la Mancha (RSEQ), Grupo especializado en Nanociencia y Materiales Moleculares (RESEQ), Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tec

New molecules based indolium for two-photon absortion bioimaging applications

The development of organic materials with 2PA has attracted intensive attention in the past two decades. In two-photon bio-imaging applications the design of the chromophore requires to have a good cross-section and good biological compatibility which depends on the molecular volume and polarity. Fluorophores based on indolenines are one of these organic materials. These compounds and related are used in fluorescence microscopy as in super-resolution. The non-invasive nature of light allows imaging of biological specimens with minimal disruption, so you can see the dynamic processes that occur in living cells and tissues. In this work, we present the design, synthesis and characterization of new indolium derivatives. These compounds are easy to achieve with good yields and good photophysical properties. In addition, time-dependent density functional theory (TDDFT) has been carried out to investigate the energy level of the ground and excited state. Also, these molecules have been proved on cells.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tec

Tuning pKa in new molecules based on indolines for two-photon absorption bioimaging applications

Fluorescence-based biosensors have become essential tools for modern biology, allowing real-time monitoring of biological processes within living cells. The differences between pH play a significant role in multiple biological process such as proliferation, apoptosis, endocytic process and defense. Therefore, intracellular fluorescent pH probes comprise one of the most widely used families of biosensors in microscopy. In this work, we present the design, synthesis and characterization of new one and two photon pH activatable fluorescent probes based on naphthalene-indoline derivatives with an off-on response to different pH environments. These compounds are easy to achieve with good yields and have good photophysical properties. Simple modifications in the structure of these compounds allow tuning their pKa easily and cover a width range of pH in their applications. The preliminary results obtained with these fluorescent probes indicate that they have promising properties to be use in bioimaging applications in living cells.Real Sociedad Española de Química y Grupo Especializado de Química Orgánica de la RSEQ•Universidade de Santiago de Compostela • CIQUS • Lilly • Mestrelab Research •Thieme •Scharlab • Acros • ABCR • AMSLab • GalChimia • Elsevier • The Journal of the American Chemical Society • ACS Omega • Organic Letters • The Journal of Organic Chemistry • Accounts of Chemical Research. Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

Evaluation of the particle geometry and interphase influence on the filler-matrix debonding process

Incorporation of rigid fillers into polymer matrices represents a widely used technique to obtain improved performance. The mechanical behavior finally obtained is closely related to a wide range of involved factors (filler type and size, internal structure, filler-matrix interaction, among others) and to activated dissipative mechanisms (debonding, plastic void growth, crazing, matrix yielding, etc). In this work, a debonding strength approach was applied for rigid particles (spherical, elliptical and fiber) surrounded by an interphase. The effect of interphase mechanical properties and thickness on the debonding process was investigated. The obtained results suggested a significant influence of the transition rigidity. In general, stiffer interphases promoted higher critical strength values. On the other hand, particle surrounded by a softer transition region displayed higher dissipated energy for all examined particle, except for spheres.Fil: Perez, Ezequiel Martin. Instituto Nacional de Tecnología Industrial; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Lauke, B.. No especifíca

Agroecological transition increases arthropod diversity and decreases herbivore abundance on field margins

In peri-urban areas, many farmers are transitioning from conventional agriculture to agroecological practices to reduce pesticide input and preserving ecosystem services such as natural pest control. Field margins represent a stable habitat for arthropods, but community structure depends on many factors, including management type and vegetation features. We studied the effects of agroecological transitions and vegetation features on arthropods of horticultural field margins, focusing on three feeding guilds (herbivores, predators and parasitoids). We sampled arthropods using the beat-sheet method in five conventional fields and five under agroecological transition. We also measured vegetation height, richness, flower abundance and plant cover. Our results showed that arthropod diversity was higher in agroecological fields whereas herbivore abundance was lower, with a consistent pattern across most taxonomic orders. Vegetation features displayed multiple effects among functional and taxonomic groups. Herbivores did not respond to most vegetation variables whereas predators correlated with several, with similar trends among orders. We conclude that agroecological transitions and field margins with high vegetation richness and floral resources influence arthropod communities with potential benefits regarding pest regulation. These practices might be more effective if considered alongside other methods that enhance biodiversity and if they are consistent at a landscape scale.Fil: Pérez Roig, Camila. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto Multidisciplinario de Biología Vegetal. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto Multidisciplinario de Biología Vegetal; ArgentinaFil: González, Ezequiel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto Multidisciplinario de Biología Vegetal. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto Multidisciplinario de Biología Vegetal; Argentina. Czech University Of Life Sciences Prague; República ChecaFil: Videla, Martin. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto Multidisciplinario de Biología Vegetal. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto Multidisciplinario de Biología Vegetal; Argentin

Detecting hydroxyl radical with a new two-photon fluorescent probe in living cells

Reactive oxygen species (ROS) are known to be involved in the onset and development of multiple diseases, including cancer, cardiovascular diseases, neurodegenerative diseases and diabetes among others. Generation of ROS is a phenomenon that results from normal cell metabolism as well as from the response to certain pathologic stimuli like certain cytokines, xenobiotics and bacterial infection. These ROS are highly reactive, short-lived molecules that play critical roles in the living cell and it is well accepted that cellular oxidative stress results from the imbalance between generation and elimination of ROS in cells. In this work, we describe the design and synthesis of a two photon (TP) organelle-targeting activatable fluorescent probe. This probe is a naphthalene-indoline compound that targets specifically lysosomes, reaching these organelles in the fluorescence “off” state and minimizing background reactions. Upon arrival at the lysosomes, the probe is triggered and a fluorescence “on” signal is observed that can be combined with TP microscopy to image the lysosomal •OH in living cells.Real Sociedad Española de Química y Grupo Especializado de Química Orgánica de la RSEQ•Universidade de Santiago de Compostela • CIQUS • Lilly • Mestrelab Research •Thieme •Scharlab • Acros • ABCR • AMSLab • GalChimia • Elsevier • The Journal of the American Chemical Society • ACS Omega • Organic Letters • The Journal of Organic Chemistry • Accounts of Chemical Research. Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tec

Proppant transport in a scaled vertical planar fracture: Vorticity and dune placement

We report experimental results on the transport of proppant in a scaled planar cell. As a complement to many previous studies, we consider, apart from a proper scaling of the experimental cell and flow rate, a scaling of the perforations through which the fracturing slurry is injected. We also consider a fracture height relatively larger than usual, compatible with thick formations such as Vaca Muerta, Neuquén basin (Argentina). Under these conditions, we find that the flow pattern in the fracture presents large vortexes. The effect on the proppant transport is significant, yielding a much deeper placement of the dune than previously observed in similar experiments. We discuss the implications for the design of hydraulic fracturing operations.Fil: Fernandez, Matías Ezequiel. YPF - Tecnología; Argentina. Universidad Tecnológica Nacional. Facultad Regional La Plata. Departamento de Ingeniería Mecánica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; ArgentinaFil: Sanchez, Martin. YPF - Tecnología; ArgentinaFil: Pugnaloni, Luis Ariel. Universidad Tecnológica Nacional. Facultad Regional La Plata. Departamento de Ingeniería Mecánica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; Argentin