Impact evaluation of marine aggregate extraction through adaptive monitoring of bottom shear stress in bedform areas

Dedicated monitoring programmes are needed for the evaluation of the effects of the exploitation of non-living resources on the territorial sea and the continental shelf. Related to physical impacts, hydrodynamics and sediment transport, together with sedimentological and morphological evolution, need investigation. Overall aim is to increase process and system knowledge of both natural and exploited areas, with a particular focus on thecompliancy of extraction activities with respect to European Directives (e.g., European Marine Strategy Framework Directive and Habitat Directive). More specifically assessments are needed of changes in seafloor integrity and hydrographic conditions, two descriptors to define Good Environmental Status within Europe’sMarine Strategy Framework Directive.An important parameter is the bottom shear stress, with knowledge needed on both natural and anthropogenically induced variability. Bottom shear stress measurements are used for the validation of numerical models, necessary for impact quantification in the far field. Extensive data-model integration is critical for adequate assessments of the status of the marine environment, a prerequisite for sustainable use of living, and non-living resources

Annual variability in the seasonal cycles of chlorophyll, nutrients and zooplankton on the North-West European continental shelf

Seasonal cycles of salinity, nutrients, chlorophyll and zooplankton at 8 locations on the West-European shelf were analysed with respect to their timing and magnitude in the period 1980-1984. A late spring bloom with low chlorophyll values (2-4 mg.m-³) is observed in the Irish Sea, off the Scottish east coast and the Channel entrance. An early spring bloom and relatively high chlorophyll values (7-12 mg.m-³) are found in the southern Bight and the Skagerrak, whereas a late spring bloom with high chlorophyll concentrations (24 mg.m-³) is found along the Dutch and Belgian coast. In contrast to the other regions, the peak of the phytoplankton cycle in the German Bight (Helgoland) occurs in the summer period instead of the spring period. The peak in the yearly abundance of copepods shifts from May-June in the south to July-August in the north of the shelf. In the Irish Sea and the Channel entrance two seasonal copepods peaks are observed. The January nitrate values in Irish Sea, the southern Bight and the Skagerrak are about 20 % higher than those in the Atlantic input signal in the Channel entrance and east off Scotland. The January DIP values in these regions are comparable to those of the input signal, but the Irish Sea forms an exception here the level is increased by 10-20%. If compared with the Atlantic input signal the January values for nitrate and DIP at the Dutch and Belgium coast are about 10 and 4, and in the German Bight (Helgoland) 4 and 3 times higher, respectively. At most sites changes in the seasonal cycles of chorophyll coincide with changes in nutrient concentrations, wheras the maximum level of the seasonal signal is related to the nutrient levels

Challenges to the development of antigen-specific breast cancer vaccines

Continued progress in the development of antigen-specific breast cancer vaccines depends on the identification of appropriate target antigens, the establishment of effective immunization strategies, and the ability to circumvent immune escape mechanisms. Methods such as T cell epitope cloning and serological expression cloning (SEREX) have led to the identification of a number target antigens expressed in breast cancer. Improved immunization strategies, such as using dendritic cells to present tumor-associated antigens to T lymphocytes, have been shown to induce antigen-specific T cell responses in vivo and, in some cases, objective clinical responses. An outcome of successful tumor immunity is the evolution of antigen-loss tumor variants. The development of a polyvalent breast cancer vaccine, directed against a panel of tumor-associated antigens, may counteract this form of immune escape

Mud Origin, Characterisation and Human Activities (MOCHA): Final report

The cohesive sediments, which are frequently found in the Belgian nearshore zone (southern North Sea), are of different age such as tertiary clays and Holocene, modern and recently deposited muds. The area is characterised by a turbidity maximum. The source areas of the recently deposited muds and the effect of human impact vs. natural processes on the distribution and/or erosion of these sediments have been investigated using historic and recent bottom samples, in situ and remote sensing (satellite images) SPM concentration measurements, numerical modelling, GIS and clay mineral and microfossil analysis. The Schelde estuary, the potential erosion areas of cohesive sediments on the BCS and adjacent areas and the SPM transport through the Dover Strait have been considered as possible source areas.The historic bottom samples have been collected in the beginning of the 20th century, the quality of these samples and the meta-information is very high and they have proven to be a major reference to understand the evolution of the cohesive sediment distribution. The recent bottom samples consist of box core, Reineck core and Van Veen grab samples collected during the last 10 years. The processing of the historic and recent data on cohesive sediments was mainly based on field descriptions of the samples (consolidation, thickness) and morphological evolution. On some of the recent samples radioactive and gamma densitometric measurements have been carried out. During the processing the emphasis was put on the occurrence of thick layers (>30 cm) of freshly deposited to very soft consolidated mud and of clay and mud pebbles, because these sediments are witnesses of changes.Satellite images, in situ measurements and a 2D hydrodynamic numerical model have been combined to calculate the long term SPM transport through the Dover Strait and in the southern North Sea. The satellite images (SeaWiFS) provide synoptic views of SPM concentration. The representativness of SPM concentration maps derived from satellites for calculating long term transports has been investigated by comparing the SPM concentration variability from the in situ measurements with those of the satellite data. It is underlined that SPM concentration measurements should be carried out during at least one tidal cycle in high turbidity areas to obtain representative values of SPM concentration.Areas where the thickness of the Quaternary cover is less than 2.5 m were defined as potential erosion areas of Palaeogene clay containing deposits. In the framework of this project, the geological data related to the BCS have been reviewed and the relevant information was compiled into a GIS. This also included a small part of the French continental shelf. Additionally information was added from vibrocores analysis and Dutch geological data. Approximately 20 % of the BCS, 6 % of the small part of the French area and only 3% of the Dutch study area could possibly serve as a source for fine suspended sediments. Quaternary muds are mostly presented in the 2 eastern nearshore area; on the Dutch part they occur more offshore. Their occurrence represents 11% of the BCS and approximately 35% of the Rabsbank area Cretaceous microfossils are present in all samples and have been transported into the area with the residual water transport. Material from the east, in particular from the Eocene-Oligocene transitional strata, has been found in the eastern nearshore area up to about Oostende. This zone coincides with the extension of the Holocene mud and could indicate an erosion of these sediments and/or a transport of clay minerals from the Schelde estuary.Clay mineral analysis has been carried by two approaches in order to determine source areas. The results of the second approach show that no systematic differences in the clay mineralogy depending on geographic location could have been found within the samples. The results clearly prove the necessity of using more elaborate sample preparation procedures in examining the provenance of the mud deposits.Thick layers of fresh mud were deposited in the beginning of the 20th century mainly in a narrow band along the coast from about Nieuwpoort up to the mouth of the Westerschelde. These deposits were mainly the result of natural morphological changes. Today, most of the depositions of thick layers of fresh mud have been induced by anthropogenic operations, such as dumping, deepening of the navigation channels and construction and extension of the port of Zeebrugge. Comparing the actual situation with the situation 100 years ago reveals that the area around Zeebrugge where fresh mud is deposited extends more offshore today

Investigation of Performance and Cavitation Treatment in a Kaplan Hydro Turbine

Cavitation is a phenomenon that occurs in various turbomachinery applications causing drawbacks on the. Some of these downsides are damaging the components of the system, generating noise and vibration, and loss of the turbine efficiency over time. Thus, it is imperative to address issue of cavitation to increase the life span of the equipment in addition to improve the system performance. This thesis introduces a method used to mitigate the cavitation phenomenon in a 3-inch Kaplan hydro turbine via injecting air at the leading edge of the rotor blades. The study is based on modeling the turbine using Computational Fluid Dynamics (CFD) software as well as carrying out experimental tests. The simulations were conducted at different air injection pressures over a spectrum of rotational speeds using Large Eddy Simulation (LES) for turbulence and volume of fluid for multiphase interactions: water, vapor water and air. The cavitation behavior was observed first without aeration, then followed by air injection simulations to investigate the effect of aeration. Each case was simulated for 12 cycles at rotational speeds of 1000, 2000, 3000, 4000, and 5000 rpm. The Vapor Volume Fraction (VVF) and the output mechanical power were monitored throughout the simulations. The data acquired from the simulations were compared to the experimental results for verifications. It was observed that the cavitation was mitigated in both the computer simulations and the experiment testing reaching up to 49.7% as an average reduction, while the output power was reduced by 6.6%