Age Effects on Lactic- and Malic-Acid Dehydrogenases in C57BL/6 Mouse Testes

Author Institution: Department of Biological Sciences, Kent State University, Kent, Ohio 44240There is evidence that lactic-acid-dehydrogenase (LDH) and malic-acid-dehydrogenase (MDH) activities vary with age in several mammalian organs. This study shows that both enzymes in the testes of the C57BL/6 mouse exhibit age-related changes. These changes are most evident when the LDH/MDH ratio is considered. The LDH/MDH ratio decreases to two days before onset of spermatogenesis, remains unchanged to one day before weaning, increases to four or five days prior to breeding activity, and oscillates through the remainder of the 365 days studied. Although these are in vitro results, activity changes occur coincident with physiological changes in the testes

Distinct information critically distinguishes judgments of face familiarity and identity

Accurately determining the familiarity of another and correctly establishing their identity are vital social skills. A considerable body of work has explored their perceptual and neural underpinnings and debate remains regarding whether they are dissociable, i.e., separable parts of a dual process, or different aspects of a common retrieval process. Less is known about the specific visual information that guides familiarity judgments and how this compares to the information used to identify a face by name. Here we sought to establish the critical information underlying participants’ judgments of facial familiarity and identification. We created a new standardized stimulus set comprising 6 personally familiar and 12 unfamiliar faces and applied the Bubbles reverse-correlation methodology to establish the information driving correct performance in each task. Results revealed that markedly different information underlies familiarity and identity judgments. When categorizing familiarity, participants relied more upon lower spatial-frequency, broad facial cues (eye and face shape) than when categorizing identity, which relied on fine details in the internal features (eyes and mouth). These results provide novel evidence of qualitatively distinct information use in familiarity and identification judgments and emphasize the importance of considering the task set for participants and their processing strategy when investigating face recognition

Fractional-order signal processing using a polymer-electrolyte transistor

Journal ArticleFractional-order systems have applications in the areas of Flight Control, Robotics, Missile Guidance, Control of Structural Vibrations of Space Platforms and Sensor Technology. Fractional-order transfer functions can characterize complex nonlinear dynamics with many fewer parameters than integer-order functions. This paper addresses the use of a polymer-electrolyte transistor (PET) for use in implementating fractional-order algorithms for signal processing. The PET's advantage over the conventional RC and RL circuits is that it can be both functionally scaled and varied for dynamic fractional-order parameter controllability

A meta-analysis of transdiagnostic cognitive behavioural therapy in the treatment of child and young person anxiety disorders

Background: Previous meta-analyses of cognitive-behavioural therapy (CBT) for children and young people with anxiety disorders have not considered the efficacy of transdiagnostic CBT for the remission of childhood anxiety. Aim: To provide a meta-analysis on the efficacy of transdiagnostic CBT for children and young people with anxiety disorders. Methods: The analysis included randomized controlled trials using transdiagnostic CBT for children and young people formally diagnosed with an anxiety disorder. An electronic search was conducted using the following databases: ASSIA, Cochrane Controlled Trials Register, Current Controlled Trials, Medline, PsycArticles, PsychInfo, and Web of Knowledge. The search terms included “anxiety disorder(s)”, “anxi∗”, “cognitive behavio∗, “CBT”, “child∗”, “children”, “paediatric”, “adolescent(s)”, “adolescence”, “youth” and “young pe∗”. The studies identified from this search were screened against the inclusion and exclusion criteria, and 20 studies were identified as appropriate for inclusion in the current meta-analysis. Pre- and posttreatment (or control period) data were used for analysis. Results: Findings indicated significantly greater odds of anxiety remission from pre- to posttreatment for those engaged in the transdiagnostic CBT intervention compared with those in the control group, with children in the treatment condition 9.15 times more likely to recover from their anxiety diagnosis than children in the control group. Risk of bias was not correlated with study effect sizes. Conclusions: Transdiagnostic CBT seems effective in reducing symptoms of anxiety in children and young people. Further research is required to investigate the efficacy of CBT for children under the age of 6

Transit-Oriented Development: An Examination of America’s Transit Precincts in 2000 & 2010

This study creates a typology of all fixed transit precincts across the United States to categorize all stations as either a Transit Oriented Development (TOD), Transit Adjacent Development (TAD) or hybrid. This typology is based on an index that accounts for density, land use diversity and walkable design. This study also presents a separate non-typological multilevel, multivariate analysis of transit commuting and the built environment, which is unique in that it is the first national study of transit station precincts of its kind to control for both regional and neighborhood level variables. The findings lend support for the TOD concept in generating higher shares of transit commuting within station areas, with implications about how America can accommodate population growth by turning TADs and hybrids into TODs. This can result in more sustainable commuting patterns, a new growth market for housing and real estate in a post-recession economy and the potential decoupling of growth in the economy without the growth in carbon emissions. Much of this could be achievable without the need to necessarily make a major national investment in new infrastructure but in utilizing the existing infrastructure better by encourage more TODs

Australian Pasture Systems: The Perennial Compromise

Dryland salinity, soil acidification and weed herbicide resistance challenge traditional agricultural production systems in south Australia. The pasture component of such systems rely on annuals like Trifolium subterraneum and Medicago spp. Replacing annual with perennial pastures allows some redress of the sustainability challenges, but few well-adapted species are available (Ewing & Dolling 2003). A range of perennial species are under evaluation to supplement current options. Some of these new perennial pastures may need modified production systems that allow full expression of their productive potential, especially when integrated with annual crops including cereals, pulses and oil seeds. Integrated systems rely on spatial or temporal segregation of pastures from crops. The necessary characteristics of plants for likely systems are discussed