1,172 research outputs found
The missing sinks: slip localization in faults, damage zones, and the seismic energy budget
No abstract available
Weak spin interactions in Mott insulating La2O2Fe2OSe2
Identifying and characterizing the parent phases of iron-based superconductors is an important step towards understanding the mechanism for their high-temperature superconductivity. We present an investigation into the magnetic interactions in the Mott insulator La2O2Fe2OSe2. This iron oxyselenide adopts a 2-k magnetic structure with low levels of magnetic frustration. This magnetic ground state is found to be dominated by next-nearest-neighbor interactions J2 and J2′ and the magnetocrystalline anisotropy of the Fe2+ site, leading to 2D-Ising-like spin S=2 fluctuations. In contrast to calculations, the values are small and confine the spin excitations below ∼25 meV. This is further corroborated by sum rules of neutron scattering. This indicates that superconductivity in related materials may derive from a weakly coupled and unfrustrated magnetic structure
The common ‘thermolabile' variant of methylene tetrahydrofolate reductase is a major determinant of mild hyperhomocysteinaemia
Mild hyperhomocysteinaemia is a major risk factor for vascular disease and neural tube defects (NTDs), conferring an approximately three-fold relative risk for each condition. It has several possible causes: heterozygosity for rare loss of function mutations in the genes for 5,10-methylene tetrahydrofolate reductase (MTHFR) or cystathionine-β-synthase (CBS); dietary insufficiency of vitamin co-factors B6, B12 or folates; or homozygosity for a common ‘thermolabile' mutation in the MTHFR gene which has also been associated with vascular disease and NTDs. We quantified the contribution of the thermolabile mutation to the hyperhomocysteinaemic phenotype in a working male population (625 individuals). Serum folate and vitamin B12 concentrations were also measured and their relationship with homocysteine status and MTHFR genotype assessed. The homozygous thermolabile genotype occurred in 48.4, 35.5, and 23.4% of the top 5,10, and 20% of individuals (respectively) ranked by plasma homocysteine levels, compared with a frequency of 11.5% in the study population as a whole, establishing that the mutation is a major determinant of homocysteine levels at the upper end of the range. Serum folate concentrations also varied with genotype, being lowest in thermolabile homozygotes. The MTHFR thermolabile genotype should be considered when population studies are designed to determine the effective homocysteine-lowering dose of dietary folate supplements, and when prophylactic doses of folate are recommended for individual
On the Truncated Pareto Distribution with applications
The Pareto probability distribution is widely applied in different fields
such us finance, physics, hydrology, geology and astronomy. This note deals
with an application of the Pareto distribution to astrophysics and more
precisely to the statistical analysis of mass of stars and of diameters of
asteroids. In particular a comparison between the usual Pareto distribution and
its truncated version is presented. Finally a possible physical mechanism that
produces Pareto tails for the distribution of the masses of stars is suggested.Comment: 10 pages 6 figure
0175 Light Improves Alertness and Mood During the Sleep Inertia Period Following Slow Wave Sleep
Funded by Naval Postgraduate SchoolThe article of record as published may be found at https://doi.org/10.1093/sleep/zsaa056.173Introduction: Waking from sleep, especially slow wave sleep (SWS), is associated with reduced alertness known as sleep inertia. Light improves alertness during sleep deprivation and circadian misalignment. In this study, we assessed the efficacy of light to improve alertness and mood immediately after waking from SWS. Methods: Twelve participants kept a sleep schedule of 8.5 h for 5 nights and 5 h for one night prior to the overnight laboratory visit (confirmed by actigraphy). Participants went to bed at their scheduled habitual bedtime in the laboratory and were monitored by standard polysomnography. After at least 5 min of SWS, participants were awoken and exposed to either red ambient light (control) or blue-enriched bright light (light) for 1 h. During this time, participants completed a subjective scale of alertness (Karolinska Sleepiness Scale, KSS) and visual analogue scales (VAS) of mood at 2 min, 17 min, 32 min, and 47 min after waking. Following this sleep inertia measurement period, all lights were turned off and participants were allowed to return to sleep. They were then awoken again from their subsequent SWS period and exposed to the opposite condition (control or light). A linear mixed-effects model with fixed effects of condition, time, and condition*time and a random effect of participant was used to determine the impact of light across the testing period. An average of baseline responses (pre-sleep) was included as a covariate. Results: Compared to the control condition, participants exposed to blue-enriched bright light reported feeling more alert (KSS: F1,77=4.955, p=.029; VASalert: F1,77=8.226, p=.005), more cheerful (VAScheerful: F1,77=8.615, p=.004), less depressed (VASdepressed: F1,77=4.649, p=.034), and less lethargic (VASlethargic: F1,77=5.652, p=.020). Conclusion: Exposure to blue-enriched bright light immediately after waking from SWS may help to improve subjective alertness and mood. Future analyses will explore whether these findings extend to effects on cognitive performance.Naval Postgraduate School Grant. NASA Airspace Operations and Safety Program, System-Wide Safety Project
Autres pays, autres coeurs. Dietary patterns, risk factors and ischaemic heart disease in Belfast and Toulouse
Revised spherically symmetric solutions of gravity
We study spherically symmetric static empty space solutions in
model of gravity. We show that the Schwarzschild
metric is an exact solution of the resulted field equations and consequently
there are general solutions which {are perturbed Schwarzschild metric and
viable for solar system. Our results for large scale contains a logarithmic
term with a coefficient producing a repulsive gravity force which is in
agreement with the positive acceleration of the universe.Comment: 8 page
The interpretive approach to religious education : challenging Thompson's interpretation
In a recent book chapter, Matthew Thompson makes some criticisms of my work, including the interpretive approach to religious education and the research and activity of Warwick Religions and Education Research Unit. Against the background of a discussion of religious education in the public sphere, my response challenges Thompson’s account, commenting on his own position in relation to dialogical approaches to religious education. The article rehearses my long held view that the ideal form of religious education in fully state funded schools of a liberal democracy should be ‘secular’ but not ‘secularist’; there should be no implication of an axiomatic secular humanist interpretation of religions
Номінація частин руки в говірці села Невгоди Овруцького району Житомирської області
У статті розглянуто лексеми на позначення частин руки в сучасній середньополіській говірці, зокрема проаналізовано їхню семантику та мотивацію.В статье рассматриваются лексемы, обозначающие части руки, в современном среднеполесском говоре, а именно проанализирована их семантика и мотивация.The article deals with lexemes on designations of parts of the manuscript in the middle-polissya dialect. Their semantics and motivation are also analyzed
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