Polyurethane/acrylic hybrid dispersions containing phosphorus reactive flame retardants as transparent coatings for wood

Phosphorus modified polyurethane/acrylic hybrid dispersions were prepared for flame retardant transparent wood coatings. The polymerisation was carried out in three steps. In the first one, the polyurethane was synthesised using an acrylic monomer as solvent. The second step involved water addition that promoted the phase inversion and lastly, acrylic part was polymerised. The phosphorous compounds were covalently linked to polyurethane using a phosphorylated polyol and to the acrylic phase using an acrylic phosphate. Polymerisation was monitored by FTIR and NMR and the molar mass of the hybrids was measured by AF4 and SEC. The effects of the phosphorus in fire-retardant properties were analysed by thermogravimetry and pyrolysis combustion flow calorimetry. The introduction of phosphorus did not produce significant changes in the polymerisation process but promoted the cross-linking of the coatings. The coated wood samples maintained the transparency and good properties with the introduction of phosphorus and presented a slight reduction in the Peak Heat Release Rate measured by cone calorimeter. The action of phosphorus as a fire retardant was effective as it gave rise to significant reduction of the CO and CO2 peaks.The funding received from University of the Basque Country (GIU19/077, predoctoral grant of M. Puyadena and postdoctoral grant of M. Cobos) and the Basque Government (IT1313-19, PIBA20/16) is grate-fully acknowledged. Technical and human support provided by SGIker is also sincerely acknowledged (UPV/EHU/ ERDF, EU

Polyurethane/acrylic hybrid dispersions containing phosphorus reactive flame retardants as transparent coatings for wood

Phosphorus modified polyurethane/acrylic hybrid dispersions were prepared for flame retardant transparent wood coatings. The polymerisation was carried out in three steps. In the first one, the polyurethane was synthesised using an acrylic monomer as solvent. The second step involved water addition that promoted the phase inversion and lastly, acrylic part was polymerised. The phosphorous compounds were covalently linked to polyurethane using a phosphorylated polyol and to the acrylic phase using an acrylic phosphate. Polymerisation was monitored by FTIR and NMR and the molar mass of the hybrids was measured by AF4 and SEC. The effects of the phosphorus in fire-retardant properties were analysed by thermogravimetry and pyrolysis combustion flow calorimetry. The introduction of phosphorus did not produce significant changes in the polymerisation process but promoted the cross-linking of the coatings. The coated wood samples maintained the transparency and good properties with the introduction of phosphorus and presented a slight reduction in the Peak Heat Release Rate measured by cone calorimeter. The action of phosphorus as a fire retardant was effective as it gave rise to significant reduction of the CO and CO2 peaks.The funding received from University of the Basque Country (GIU19/077, predoctoral grant of M. Puyadena and postdoctoral grant of M. Cobos) and the Basque Government (IT1313-19, PIBA20/16) is gratefully acknowledged. Technical and human support provided by SGIker is also sincerely acknowledged (UPV/EHU/ERDF, EU)

Idoneidad de la prescripción antibiótica en atención primaria en la Comunidad Autónoma Vasca

ObjetivoEstudiar la variabilidad e idoneidad de la prescripción antibiótica en atención primaria en la Comunidad Autónoma Vasca (CAV).DiseñoEstudio descriptivo, prospectivo.EmplazamientoCentros de atención primaria de la red reformada y no reformada de la CAV.Mediciones y resultados principalesSe estudiaron 3.182 infecciones obtenidas de consultas sobre enfermedad infecciosa mediante muestreo estratificado por área sanitaria durante febrero, marzo y abril de 1998. La idoneidad de la prescripción de antibióticos (ATB) se comparó con unos patrones elaborados tras una extensa revisión bibliográfica. Un 68,6% de las consultas son infecciones que no requieren ATB (catarro de vías altas [IRA], bronquitis aguda, gripe y gastroenteritis). Se utilizan ATB en un 28,5% de estos casos (IC, 26,6-30,5). Destaca la bronquitis aguda, con un 90,7% (IC, 87,3-93,4). La prescripción innecesaria supone un 39,7% de la prescripción total antibiótica (IC, 37,2-42,1%), suponiendo un gasto anual innecesario de 1.155 millones de pesetas.En el 31,4% de las infecciones que requieren tratamiento con ATB, se opta por uno no adecuado en un 23,7% (IC, 21-26,7%).En total, la idoneidad del tratamiento global fue del 72,2% (IC, 70,6-73,8). El hecho de trabajar en la red reformada se asoció a una mejor prescripción en todos los casos. Los pediatras prescriben mejor en el caso de las infecciones no susceptibles de tratamiento con ATB.ConclusionesLa prescripción de ATB no se realiza conforme a la evidencia científica disponible. Los tratamientos incorrectos tienen lugar sobre todo en procesos benignos y autolimitados. Es necesaria una política local de uso de ATB que incluya colaboración multidisciplinaria y formación continuada efectiva.ObjectiveTo study the variability and suitability of antibiotic prescription in primary care in the Basque Country.DesignProspective, descriptive study.SettingBasque Country health care centres both within and not in the reformed network.Measurements and main results3182 infections from consultations for infectious disease were studied through sampling stratified by health area during February, March and April 1998. The appropriateness of antibiotics (ATB) prescription was compared with some standards after an extensive bibliographic review. 68.6% of consultations were infections not needing ATB (infections of respiratory airways, acute bronchitis, flu and gastro-enteritis). ATB were used in 28.5% of these cases (CI: 26.6-30.5), especially in acute bronchitis (90.7%) (CI: 87.3-93.4). Unnecessary prescription supposes 39.7% of total antibiotic prescription (CI: 37.2-42.1%), which means unnecessary annual expenditure of 1155 million pesetas. In 31.4% of the infections that require ATB treatment, in 23.7% inappropriate treatment was chosen (CI: 21-26.7%). Overall appropriateness of treatment was 72.2% (CI: 70.6-73.8). Working in the reformed system was linked to better prescription in all cases. Paediatricians prescribed better in the case of infections not susceptible to ATB treatment.ConclusionsATB prescription is not consistent with the available scientific evidence. Incorrect treatments occur especially in benign and self-limiting processes. A local policy of ATB use that includes multi-disciplinary collaboration and effective ongoing training is necessary

The VALU3S ECSEL project: Verification and validation of automated systems safety and security

Manufacturers of automated systems and their components have been allocating an enormous amount of time and effort in R&D activities, which led to the availability of prototypes demonstrating new capabilities as well as the introduction of such systems to the market within different domains. Manufacturers need to make sure that the systems function in the intended way and according to specifications. This is not a trivial task as system complexity rises dramatically the more integrated and interconnected these systems become with the addition of automated functionality and features to them. This effort translates into an overhead on the V&V (verification and validation) process making it time-consuming and costly. In this paper, we present VALU3S, an ECSEL JU (joint undertaking) project that aims to evaluate the state-of-the-art V&V methods and tools, and design a multi-domain framework to create a clear structure around the components and elements needed to conduct the V&V process. The main expected benefit of the framework is to reduce time and cost needed to verify and validate automated systems with respect to safety, cyber-security, and privacy requirements. This is done through identification and classification of evaluation methods, tools, environments and concepts for V&V of automated systems with respect to the mentioned requirements. VALU3S will provide guidelines to the V&V community including engineers and researchers on how the V&V of automated systems could be improved considering the cost, time and effort of conducting V&V processes. To this end, VALU3S brings together a consortium with partners from 10 different countries, amounting to a mix of 25 industrial partners, 6 leading research institutes, and 10 universities to reach the project goal.VALU3S (verification and validation of automated systems' safety and security