Evaluation of the antidiarrhoeal effect of Vitellaria paradoxa Gaertn F (Sapotaceae) stem bark extract

The antidiarrhoeal property of the methanolic stem bark extract of Vitellaria paradoxa was studied in mice. The assessment parameters included, castor oil induced diarrhoea, intestinal transit time, enteropooling. The antidiarrhoeal evaluation of the extract showed that it significantly reduced castor oil induced diarrhoea in mice dose dependently (100-400 mg/kg). The methanolic extract of Vitellaria paradoxa significantly (p<0.05) increased intestinal transit time of charcoal in mice dose dependently. The extract was also observed to reduce the castor oil induced enteropooling in mice. Vitellaria paradoxa methanol stem bark extract may possess antidiarrhoeal property. Key words: Antidiarrhoeal, Castor-oil, Enteropooling, Transit time, Vitellaria paradoxa

Growth Performance, Carcass and Organ Characteristics of Pullets Fed Plantain Ash Supplemented Commercial Diets

The main objective of this study was to compare the effects of different plantain ash sources (plantain root base ash (PRA) and plantain stalk ash (PSA) supplementation on the performance of pullets fed commercial diets. Ninety six Isa brown pullets aged 15 weeks were therefore used to assess the effect of supplementing commercial diets with plantain root base (PRA) and stalk ashes (PSA) on growth performance, carcass and organ characteristics of pullets during 4 weeks before point of laying (19 weeks of age) and 6 weeks of laying period (25 weeks of age). The pullets were divided into two groups of 48 each for supplementation with either PSA or PRA. Each group was divided into four groups of 12, which were further replicated 3 times with 4 birds per replicate in a completely randomized design. At each developmental stage, the feed offered to the birds was supplemented with 0 (control), 1, 2, and 3 g/kg body weight of PSA or PRA. One g/kgBW of PRA supplementation elicited observable growth performance effects on the birds, while for PSA it was 2 g/kgBW. The 2 g/kgBW PSA supplemented birds gained significantly (P<0.05) more weight than the other groups except the control, which consumed significantly (P<0.05) more feed. At point of laying, the 1g/kgBW PRA group recorded significantly (P<0.05) higher body weight and weight gain than the control. Plantain root base ash affected dressing percentage significantly (P<0.05) resulting in higher thigh weights, while organ weights decreased with increasing ash supplementation levels. Plantain ash therefore has positive effect on growth and edible carcass cut. Key words: plantain ash, pullets, feed, carcas

Herbs and Spices: Options for Sustainable Animal Production

Herbs and spices and a host of other plant derivatives used in animal feeding as feed additives are referred to as phytogenic feed additives. This class of feed additives is increasingly gaining popularity in livestock production. A number of studies have demonstrated antioxidative and antimicrobial efficacy in vitro. Methane reducing effects of some herbs and spices in ruminants have also been reported. Studies show that some of these plant materials improved the palatability of feed. There are suggestions that they may specifically enhance activities of digestive enzymes and nutrient absorption. Experimental comparisons of these phytogenic additives with antibiotics and organic acids have suggested similar effects on the gut. This include reduced bacterial colony counts, fewer fermentation products, greater nutrient digestion and probably reflecting an overall improved gut equilibrium. In addition, some of the herbs and spices or their derivatives have been reported to promote intestinal mucus production. This effect may explain improved production performance after including these phytogenic feed additives. In general, available literature suggests that phytogenic feed additives such as herbs and spices may add to the set of non-antibiotic growth promoters for use in livestock like organic acids and probiotics. However, a systematic approach toward the efficacy and safety of phytogenic materials used as feed ingredients or additives is needed. There should also be studies to show the possible interaction of these plant materials with other feed ingredients in vivo. There is also the need to study herbs and spices which are indigenous to the tropics for their utilization in livestock production. Keywords: Herbs, Spices, Antimicrobial, Antioxidant, Phytogenic Feed Additive, Performance

Building Bridges with Boats: Preserving Community History through Intra- and Inter-Institutional Collaboration

This chapter discusses Launching through the Surf: The Dory Fleet of Pacific City, a project which documents the historical and contemporary role of dory fishers in the life of the coastal village of Pacific City, Oregon, U.S. Linfield College’s Department of Theatre and Communication Arts, its Jereld R. Nicholson Library, the Pacific City Arts Association, the Pacific City Dorymen\u27s Association, and the Linfield Center for the Northwest joined forces to engage in a collaborative college and community venture to preserve this important facet of Oregon’s history. Using ethnography as a theoretical grounding and oral history as a method, the project utilized artifacts from the dory fleet to augment interview data, and faculty/student teams created a searchable digital archive available via open access. The chapter draws on the authors’ experiences to identify a philosophy of strategic collaboration. Topics include project development and management, assessment, and the role of serendipity. In an era of value-added services where libraries need to continue to prove their worth, partnering with internal and external entities to create content is one way for academic libraries to remain relevant to agencies that do not have direct connections to higher education. This project not only developed a positive “town and gown” relationship with a regional community, it also benefited partner organizations as they sought to fulfill their missions. The project also serves as a potential model for intra- and inter-agency collaboration for all types of libraries

The role of the entrepreneurial university in building an entrepreneurial ecosystem in a post conflict economy: an exploratory study of Rwanda

The purpose of this paper is to examine the role of the entrepreneurial university in supporting the development of the entrepreneurial ecosystem in a post conflict, transitional economy. We developed a cross case analysis to identify common themes and patterns in the data. Our findings demonstrate that in a post conflict, transitional economy entrepreneurial universities entrepreneurial ecosystem development is constrained by a number of institutional factors including, structures, systems, leadership, strategies, and culture. We further identify that, when an entrepreneurial ecosystem system has been destroyed during conflict, these constraints present significant challenges to the evolution of the entrepreneurial ecosystem post conflict. Second, in a departure from other studies, our findings also outline the role of the entrepreneurial university in the unique evolution of the post conflict entrepreneurial ecosystem in Rwanda. We identify that the entrepreneurial ecosystem evolves through a number of stages including, embryonic, destruction, formation, and capacity building stages

A giant ectopic hidradenoma papilliferum in a Niger delta region of Nigeria

Hidradenoma papilliferum is a known example of adnexal skin tumours with apocrine differentiation. It is a rare benign tumour which tends to arise from areas with rich concentration of aporine glands such as anogenital region, vulval, perineal, axillae, and periumbilical areas. In this report, the tumour was found in the upper outer quadrant of left breast, being one of the ectopic sites for this tumour. Contrary to most reports where male preponderance was popular for ectopic hidradenoma papilliferum, the patient in this report is a 71-year-old female. Considering the location of this tumour in this report, the likely histopathological differential diagnoses such as tubular apocrine adenoma, clear cell (apocrine) adenoma, lipoma, intraductal papilloma and papillary carcinoma of the breast should be considered for exclusion. This is the first reported case of a giant ectopic hidradenoma papilliferum of the breast in a Niger Delta region of Nigeria which also highlights the role of fine needle aspiration and cytology in the diagnosis of breast lesions

Maternal and neonatal factors associated with mode of delivery under a universal newborn hearing screening programme in Lagos, Nigeria

<p>Abstract</p> <p>Background</p> <p>Emerging evidence from a recent pilot universal newborn hearing screening (UNHS) programme suggests that the burden of obstetric complications associated with mode of delivery is not limited to maternal and perinatal mortality but may also include outcomes that undermine optimal early childhood development of the surviving newborns. However, the potential pathways for this association have not been reported particularly in the context of a resource-poor setting. This study therefore set out to establish the pattern of delivery and the associated neonatal outcomes under a UNHS programme.</p> <p>Methods</p> <p>A cross-sectional study in which all consenting mothers who delivered in an inner-city tertiary maternity hospital in Lagos, Nigeria from May 2005 to December 2007 were enrolled during the UNHS programme. Socio-demographic, obstetric and neonatal factors independently associated with vaginal, elective and emergency caesarean deliveries were determined using multinomial logistic regression analyses.</p> <p>Results</p> <p>Of the 4615 mothers enrolled, 2584 (56.0%) deliveries were vaginal, 1590 (34.4%) emergency caesarean and 441 (9.6%) elective caesarean section. Maternal age, parity, social class and all obstetric factors including lack of antenatal care, maternal HIV and multiple gestations were associated with increased risk of emergency caesarean delivery compared with vaginal delivery. Only parity, lack of antenatal care and prolonged/obstructed labour were associated with increased risk of emergency compared with elective caesarean delivery. Infants delivered by vaginal method or by emergency caesarean section were more likely to be associated with the risk of sensorineural hearing loss but less likely to be associated with hyperbilirubinaemia compared with infants delivered by elective caesarean section. Emergency caesarean delivery was also associated with male gender, low five-minute Apgar scores and admission into special care baby unit compared with vaginal or elective caesarean delivery.</p> <p>Conclusions</p> <p>The vast majority of caesarean delivery in this population occur as emergencies and are associated with socio-demographic factors as well as several obstetric complications. Mode of delivery is also associated with the risk of sensorineural hearing loss and other adverse birth outcomes that lie on the causal pathways for potential developmental deficits.</p

Time-to-pregnancy and pregnancy outcomes in a South African population

<p>Abstract</p> <p>Background</p> <p>Time-to-pregnancy (TTP) has never been studied in an African setting and there are no data on the rates of adverse pregnancy outcomes in South Africa. The study objectives were to measure TTP and the rates of adverse pregnancy outcomes in South Africa, and to determine the reliability of the questionnaire tool.</p> <p>Methods</p> <p>The study was cross-sectional and applied systematic stratified sampling to obtain a representative sample of reproductive age women for a South African population. Data on socio-demographic, work, health and reproductive variables were collected on 1121 women using a standardized questionnaire. A small number (n = 73) of randomly selected questionnaires was repeated to determine reliability of the questionnaire. Data was described using simple summary statistics while Kappa and intra-class correlation statistics were calculated for reliability.</p> <p>Results</p> <p>Of the 1121 women, 47 (4.2%) had never been pregnant. Mean gravidity was 2.3 while mean parity was 2.0 There were a total of 2467 pregnancies; most (87%) resulted in live births, 9.5% in spontaneous abortion and 2.2% in still births. The proportion of planned pregnancies was 39% and the median TTP was 6 months. The reliability of the questionnaire for TTP data was good; 63% for all participants and 97% when censored at 14 months. Overall reliability of reporting adverse pregnancy outcomes was very high, ranging from 90 - 98% for most outcomes.</p> <p>Conclusion</p> <p>This is the first comprehensive population-based reproductive health study in South Africa, to describe the biologic fertility of the population, and provides rates for planned pregnancies and adverse pregnancy outcomes. The reliability of the study questionnaire was substantial, with most outcomes within 70 - 100% reliability index. The study provides important public information for health practitioners and researchers in reproductive health. It also highlights the need for public health intervention programmes and epidemiological research on biologic fertility and adverse pregnancy outcomes in the population.</p

Male responsibility and maternal morbidity: a cross-sectional study in two Nigerian states

<p>Abstract</p> <p>Background</p> <p>Nigeria continues to have high rates of maternal morbidity and mortality. This is partly associated with lack of adequate obstetric care, partly with high risks in pregnancy, including heavy work. We examined actionable risk factors and underlying determinants at community level in Bauchi and Cross River States of Nigeria, including several related to male responsibility in pregnancy.</p> <p>Method</p> <p>In 2009, field teams visited a stratified (urban/rural) last stage random sample of 180 enumeration areas drawn from the most recent censuses in each of Bauchi and Cross River states. A structured questionnaire administered in face-to-face interviews with women aged 15-49 years documented education, income, recent birth history, knowledge and attitudes related to safe birth, and deliveries in the last three years. Closed questions covered female genital mutilation, intimate partner violence (IPV) in the last year, IPV during the last pregnancy, work during the last pregnancy, and support during pregnancy. The outcome was complications in pregnancy and delivery (eclampsia, sepsis, bleeding) among survivors of childbirth in the last three years. We adjusted bivariate and multivariate analysis for clustering.</p> <p>Findings</p> <p>The most consistent and prominent of 28 candidate risk factors and underlying determinants for non-fatal maternal morbidity was intimate partner violence (IPV) during pregnancy (ORa 2.15, 95%CIca 1.43-3.24 in Bauchi and ORa 1.5, 95%CI 1.20-2.03 in Cross River). Other spouse-related factors in the multivariate model included not discussing pregnancy with the spouse and, independently, IPV in the last year. Shortage of food in the last week was a factor in both Bauchi (ORa 1.66, 95%CIca 1.22-2.26) and Cross River (ORa 1.32, 95%CIca 1.15-1.53). Female genital mutilation was a factor among less well to do Bauchi women (ORa 2.1, 95%CIca 1.39-3.17) and all Cross River women (ORa 1.23, 95%CIca 1.1-1.5).</p> <p>Interpretation</p> <p>Enhancing clinical protocols and skills can only benefit women in Nigeria and elsewhere. But the violence women experience throughout their lives – genital mutilation, domestic violence, and steep power gradients – is accentuated through pregnancy and childbirth, when women are most vulnerable. IPV especially in pregnancy, women's fear of husbands or partners and not discussing pregnancy are all within men's capacity to change.</p