Price and Cost Impacts of Concentration in Food Manufacturing Revisited

This study estimates the elasticities of wholesale food prices, cost efficiency, and market power with respect to industrial concentration in 35 food processing industries, modifying the model of Lopez, Azzam, and Lirón-España (2002). In contrast to the results of their earlier analysis, findings of this study indicate that further increases in concentration would result in significant processing cost savings (and Lerner index increases) in nearly all industries and that output prices would decline in nearly 50% of the industries, although significantly so in only 20% of them. As industrial concentration rises, price declines occur in industries with low levels of concentration while price increases occur in highly concentrated industries.cost efficiency, food prices, food processing, industrial concentration, market power, Marketing, Production Economics, Productivity Analysis,

When is Concentration Beneficial?

This paper separates market power and efficiency effects of concentration in a sample of 255 U.S. manufacturing industries and computes welfare changes from rises in concentration. The empirical findings reveal that in nearly two-third of the cases, consumers lose as efficiency gains are generally pocketed by the industries. From an aggregate welfare standpoint, concentration is found to be beneficial in nearly 70% of the cases, mostly for low and moderate levels of concentration being particularly against the public interest in highly concentrated markets. Overall, the results support the existing U.S. Federal Trade Commission guidelines for approval of mergers.concentration, marked power, efficiency, manufacturing, Industrial Organization,

Market Power and/or Efficiency: An Application to U.S. Food Processing

This article separates oligopoly-power and cost-efficiency effects of changes in industrial concentration and assesses their impact on output prices in 32 food-processing industries. Empirical results indicate that although concentration induces cost efficiency in one-third of the industries, oligopoly-power effects either dominate cost efficiency or reinforce inefficiency, resulting in higher output prices in most industries. The article also provides fresh econometric estimates of oligopoly power and economies of size for the industries in question.industrial concentration, economies of scale, industrial organization, oligopoly power, food processing, Agribusiness, Industrial Organization, Productivity Analysis, L00, L11, L13, L66,

Fabrication and characterisation of Si micropillar PV structures

Arrays of vertical silicon micropillar radial junction solar cells have been fabricated by diffusion of direct application spin on dopant and from the vapour phase through proximity rapid thermal diffusion. The micropillars were fabricated by optical lithography and deep reactive ion etching. The micropillar arrays show superior antireflective properties over the measured spectrum and good correlation to finite difference time domain modelling of identical geometry arrays. Junctions formed by a conventional spin on doping process of phosphorus containing dopant solution produced Suns-Voc values in the region of 0·3 V. This value is likely due to difficulties encountered in achieving an even distribution of dopant over the entire surface of the arrays. An alternative method utilising spin on dopant but employing an intermediate vapour phase diffusion step produced promising results with Suns-Voc values reaching 0·5 V following a post-diffusion drive-in ste

Fabrication and characterisation of Si micropillar PV structures

Arrays of vertical silicon micropillar radial junction solar cells have been fabricated by diffusion of direct application spin on dopant and from the vapour phase through proximity rapid thermal diffusion. The micropillars were fabricated by optical lithography and deep reactive ion etching. The micropillar arrays show superior antireflective properties over the measured spectrum and good correlation to finite difference time domain modelling of identical geometry arrays. Junctions formed by a conventional spin on doping process of phosphorus containing dopant solution produced Suns-Voc values in the region of 0.3 V. This value is likely due to difficulties encountered in achieving an even distribution of dopant over the entire surface of the arrays. An alternative method utilising spin on dopant but employing an intermediate vapour phase diffusion step produced promising results with Suns-Voc values reaching 0.5 V following a post-diffusion drive-in step

A minimally invasive, lentiviral based method for the rapid and sustained genetic manipulation of renal tubules.

The accelerated discovery of disease-related genes emerging from genomic studies has strained the capacity of traditional genetically engineered mouse models (GEMMs) to provide in-vivo validation. Direct, somatic, genetic engineering approaches allow for accelerated and flexible genetic manipulation and represent an attractive alternative to GEMMs. In this study we investigated the feasibility, safety and efficiency of a minimally invasive, lentiviral based approach for the sustained in-vivo modification of renal tubular epithelial cells. Using ultrasound guidance, reporter vectors were directly injected into the mouse renal parenchyma. We observed transgene expression confined to the renal cortex (specifically proximal and distal tubules) and sustained beyond 2 months post injection. Furthermore, we demonstrate the ability of this methodology to induce long-term, in-vivo knockdown of candidate genes either through somatic recombination of floxed alleles or by direct delivery of specific shRNA sequences. This study demonstrates that ultrasound-guided injection of lentiviral vectors provides a safe and efficient method for the genetic manipulation of renal tubules, representing a quick and versatile alternative to GEMMs for the functional characterisation of disease-related genes.The authors wish to thank the core facilities (Biological Research Unit, Histopathology, Flow Cytometry and Microscopy) of the CRUK Cambridge Institute for advice and technical assistance. This work was funded by a CRUK Clinician Scientist Fellowship award (C37839/A12177).This is the final version. It was first published by NPG at http://www.nature.com/srep/2015/150605/srep11061/full/srep11061.html

M31's Heavy Element Distribution and Outer Disk

Hubble Space Telescope imaging of 11 fields in M31 were reduced to color-magnitude diagrams. The fields were chosen to sample all galactocentric radii to 50 kpc. Assuming that the bulk of the sampled stellar populations are older than a few Gyr, the colors of the red giants map to an abundance distribution with errors of order 0.1 dex in abundance. The radially sampled abundance distributions are all about the same width, but show a mild abundance gradient that flattens outside ~20 kpc. The various distributions were weighted and summed with the aid of new surface brightness profile fits to obtain an abundance distribution representative of the entirety of M31. M31 is a system near chemical maturity. This ``observed closed box'' is compared to analytical closed box models. M31 suffers from a lack of metal-poor stars and metal-rich stars relative to the simplest closed-box model in the same way as the solar neighborhood.Comparing to several simple chemical evolution models, neither complete mixing of gas at all times nor zero mixing, inhomogeneous models give the most convincing match to the data. As noted elsewhere, the outer disk of M31 is a factor of ten more metal-rich than the Milky Way halo, ten times more metal-rich than the dwarf spheroidals cospatial with it, and more metal-rich than most of the globular clusters at the same galactocentric radius. Difficulties of interpretation are greatly eased if we posit that the M31 disk dominates over the halo at all radii out to 50 kpc. In fact, scaling from current density models of the Milky Way, one should not expect to see halo stars dominating over disk stars until beyond our 50 kpc limit. A corollary conclusion is that most published studies of the M31 "halo" are actually studies of its disk.Comment: 28 pages, 11 black-and-white figures, in press, Astrophysical Journa

Onecut-dependent Nkx6.2 transcription factor expression is required for proper formation and activity of spinal locomotor circuits.

In the developing spinal cord, Onecut transcription factors control the diversification of motor neurons into distinct neuronal subsets by ensuring the maintenance of Isl1 expression during differentiation. However, other genes downstream of the Onecut proteins and involved in motor neuron diversification have remained unidentified. In the present study, we generated conditional mutant embryos carrying specific inactivation of Onecut genes in the developing motor neurons, performed RNA-sequencing to identify factors downstream of Onecut proteins in this neuron population, and employed additional transgenic mouse models to assess the role of one specific Onecut-downstream target, the transcription factor Nkx6.2. Nkx6.2 expression was up-regulated in Onecut-deficient motor neurons, but strongly downregulated in Onecut-deficient V2a interneurons, indicating an opposite regulation of Nkx6.2 by Onecut factors in distinct spinal neuron populations. Nkx6.2-null embryos, neonates and adult mice exhibited alterations of locomotor pattern and spinal locomotor network activity, likely resulting from defective survival of a subset of limb-innervating motor neurons and abnormal migration of V2a interneurons. Taken together, our results indicate that Nkx6.2 regulates the development of spinal neuronal populations and the formation of the spinal locomotor circuits downstream of the Onecut transcription factors

Hut-Like Pillar Si Solar Cells

This paper introduces an exciting new hut-like texturing pattern that shows lower reflectance than pyramids and nanowires in the shorter and longer wavelengths respectively