Quasi-free limit in the deuteron-deuteron three-body break-up process

Detailed measurements of vector and tensor analyzing powers of the 2H(~d, dp)n breakup process are presented. The data were obtained using a polarized deuteron-beam with an energy of 65 MeV/nucleon impinging on a liquid-deuterium target. The experiment was conducted at the AGOR facility at KVI using the BINA 4 -detection system. The focus of this contribution is to analyze data of the dd scattering process in the regime at which the neutron acts as a spectator, which we refer to as the quasi-free (QF) limit. To achieve this, events for which the final-state deuteron and proton are coplanar have been analyzed and the data have been sorted for various reconstructed momenta of the missing neutron. In the limit of vanishing neutron momentum and at small deuteron-proton momentum transfer, the data match very well with measured and predicted spin observables of the elastic deuteron-proton scattering process. The agreement deteriorates rapidly with increasing neutron momentum and deuteron-proton momentum transfer. The results of coplanar configurations in four-body phase space are compared with the results of recent available theoretical calculations based on the Single-Scattering Approximation

Three-nucleon force effects in proton-deuteron break-up studied with BINA at 135 MeV

De kracht tussen twee elektrisch geladen objecten, bekend als de Coulomb-kracht, is evenredig met hun ladingen en omgekeerd evenredig met het kwadraat van de onderlinge afstand. Deze kracht kan goed worden beschreven door de uitwisseling van een massaloos deeltje, het foton. De Coulomb-kracht is afstotend voor deeltjes met gelijke lading, zoals de protonen in atoomkernen. Daarom zou men naïef kunnen verwachten dat protonen niet tot kernen gebonden kunnen blijven. De reden dat protonen, of algemener nucleonen (protonen en neutronen), toch kernen kunnen vormen is vanwege het bestaan van een tweede kracht, de zogenaamde sterke kernkracht. Deze kracht is veel sterker dan de Coulomb-kracht en is het gevolg van de sterke wisselwerking tussen de meest elementaire bouwstenen van nucleonen, namelijk quarks en gluonen. ... Zie: Samenvatting

Inverse bremsstrahlung absorption in magnetized plasmas

The Magneto-Inertial Fusion (MIF) approach has the benefits of both approaches of Inertial Confinement Fusion (ICF) and Magnetic Confinement Fusion (MCF). MIF is a complete approach, as compared to others. It has the advancement of the common ICF and some advantages over MCF. It also includes high-density plasma in the presence of strong magnetic fields. In this study, we investigate the inverse bremsstrahlung absorption (IBA) in magnetized plasma and the kinetic theory. Many researchers have calculated the inverse bremsstrahlung absorption coefficient through the ICF approach. In this investigation, however, the average of IBA is obtained that can be used in the MIF approach, the kinetic theory and the Krook collision frequency. In addition, the influences of some parameters such as laser wavelength, electron temperature, and static magnetic field are shown on the mean collisional absorption. A numerical solution is also used to calculate the dispersion function and the laser electric field. IBA is one of the basic heating processes in laser fusion plasma. The results of the study show that, in critical layers, the increase of absorption is proportional to short laser wavelength, low electron temperature, but IBA varies slowly with the static magnetic field

Current stage of studies of the star configurations at intermediate energies with the use of the BINA detector

The Space Star Anomaly in proton-deuteron breakup cross-section occurs at energies of about 10 MeV. Data for higher energies are sparse. Therefore, a systematic scan over star configurations in the range of intermediate energies between 50 and 100 MeV/nucleon is carried out on the basis of data collected with the large acceptance BINA detector. The preliminary cross section results for forward star configurations at 80 MeV/nucleon slightly surpass the theoretical calculations, but the systematic uncertainties are still under study. Also, a new variable describing rotation of star configurations is proposed

Determination of phase space region for cross-check validation of the neutron detection in the BINA experiments

Deuteron breakup reactions are basic laboratories for testing nuclear force models. Recent improvements in the data analysis allow for direct identification of neutrons in the BINA detection setup. This opens up the opportunity to study new aspects of few-nucleon system dynamics like charge dependence of nuclear force or Coulomb interaction. In this paper we determine regions along the kinematical curves where differential cross section of deuteron-proton breakup reactions can be measured by the proton-neutron and proton-proton coincidences simultaneously. This is particularly useful for validation of the neutron detection technique

SD1000: High Sustained Viral Response Rate in 1361 Patients With Hepatitis C Genotypes 1, 2, 3, and 4 Using a Low-cost, Fixed-dose Combination Tablet of Generic Sofosbuvir and Daclatasvir: A Multicenter, Phase III Clinical Trial

Background. The combination of sofosbuvir and daclatasvir is a potent, pangenotypic regimen suitable for mass-scale hepatitis C treatment, especially in resource-limited countries where newer, expensive combinations are not available. This combination has been widely tested on genotype 4. However, Phase III trials of this combination in other genotypes have been cost prohibitive. With the introduction of generic, low-cost sofosbuvir and daclatasvir, large-scale studies in resource-limited countries are now possible. Methods. Sofosbuvir at 400 mg and daclatasvir at 60 mg were coformulated into a fixed-dose combination (FDC) tablet (Sovodak, Rojan Pharma, Tehran, Iran). Patients from 46 centers were dosed for 12 or 24 weeks with or without ribavirin, in line with existing guidelines. Responses to treatment were evaluated 12 weeks after the end of treatment (for a sustained virological response at Week 12; SVR12). Results. There were 1361 patients recruited. Overall, the patients were 21% female, with a mean age of 50 years; 39% were cirrhotic; 22% were treatment-experienced; 47% were genotype 1, 41% were genotype 3, and 2% were other genotypes. The genotype was not known in 10% of the patients. The intention-to-treat and per-protocol SVR12 rates were 94.7% and 98.8%, respectively. The safety profile was unremarkable, treatment was well tolerated, and compliance with the single-tablet regimen was excellent. Conclusions. The treatment with FDC of sofosbuvir and daclatasvir achieved high SVR12 rates, equivalent to those seen in Phase III trials of other pangenotypic options, and has been conducted at a similar scale in a representative, real-world population at a cost of under $100 per patient, which makes this combination suitable for elimination protocols in resource-limited countries. Keywords:sofosbuvir; daclatasvir; Hepatitis C; sustained virological response; generic drug