9 research outputs found
A self-watching model of analogy-making and perception
- Author
- Bento C
- Blank D
- Carbonell J
- Cardoso A
- Chi M
- Eskridge TC
- Forbus KD
- French RM
- Gasser M
- Halford GS
- Hofstadter DR
- Hofstadter DR
- Hofstadter DR
- Holyoak KJ
- Holyoak KJ
- Hummel JE
- James B. Marshall
- Kanerva P
- Kanerva P
- Kokinov BN
- Kokinov BN
- Kokinov BN
- Kolodner J
- Kolodner J
- Leake DB
- Marshall JB
- Mitchell M
- Plate TA
- Smith EE
- Veloso M
- Wilson WH
- Publication venue
- 'Informa UK Limited'
- Publication date
- Field of study
Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease
- Author
- A Abbate
- A Abhyankar
- A Adams
- A Agafina
- A Akyea-Djamson
- A Alan
- A Alfieri
- A Alfrey
- A Alvarisqueta
- A Amos
- A Anadiotis
- A Anneveldt
- A Antolick
- A Arthur
- A Aslam
- Abaci F
- Abdullakutty J
- Abhaichand R
- Abib E Jr
- Aboufakher R
- Abrantes J
- Abreu M
- Abulencia K
- Acampora D
- Acampora M
- Accini Mendoza Jl
- Aceto L
- Acevedo B
- Acevedo L
- Acheatel R
- Actis Mv
- Adams M
- Adjic Nc
- Affaki Gs
- Agarwal Dk
- Aggarwal Rk
- Agosta Gf
- Aguilar M
- Aguilar M
- Ahire N
- Ahmad I
- Ahmed Sh
- Ahn Y
- Aish B
- Aiub F
- Aiub J
- Ajax K
- Ajioka M
- Akai Y
- Akatova E
- Akrap B
- Al Joundi T
- Al-Khalili F
- Albisu J
- Alcalde Jm
- Alcide P
- Alfonso T
- Allen J
- Alllison Dc
- Almaliky T
- Amerena J
- Andersen K
- Andor M
- Angelova I
- Angiolillo D
- Anita S
- Anker Sd
- Antalik L
- Antonicelli R
- Aparicio Cv
- Apel T
- Apostolovic S
- Ara M
- Aragorn L
- Arango Jl
- Araujo Fonseca M
- Ardissino D
- Arenas Leon Jl
- Arevalo S
- Argiolas G
- Arif I
- Armas E
- Aron G
- Arora S
- Asafu-Adjaye N
- Ashcom T
- Ashford M
- Ashino K
- Asim Oktay Ao
- Assarsson E
- Ata B
- Ather N
- Atieh M
- Aull L
- Avalos V
- Avdonina N
- Awasthi Ak
- Axthelm C
- Ayala M
- Ayasse D
- Ayasse M
- Azizad M
- Azize Gm
- B Becker
- Baar M
- Babu R
- Backer T
- Badea C
- Baden M
- Baehl S
- Baek C
- Baeumer A
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- Bai A
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- Bailey S
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- Baker A
- Baker C
- Bakhai A
- Bakker H
- Baksi A
- Baldin Mg
- Bali Hk
- Ballantyne C
- Ballmajo M
- Balode A
- Balukova E
- Bang Sa
- Banker D
- Banker K
- Baquero A
- Barbarash Ol
- Barbato E
- Barbosa E
- Barnett S
- Baron S
- Barreto M
- Barroso A
- Barroso W
- Bartkowiak A
- Bartosh L
- Bartuseviciene S
- Bashir K
- Baszak J
- Bata Ir
- Bayram E
- Beall K
- Beaudry M
- Beauregard La
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- Belle Isle J
- Belohlavek J
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- Benedetti G
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- Benton J
- Berdoff R
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- Bhadade S
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- Bilodeau N
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- Blankenberg S
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- Bloch S
- Blom Kb
- Bluemel J
- Blumberg C
- Blumenthal R
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- Bolsmann C
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- Boyarkin M
- Bradley A
- Brady L
- Bramlet D
- Brath H
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- Bredlau C
- Brickman T
- Briggs S
- Briké C
- Brodmann M
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- Brousalis L
- Brouwer M
- Brown C
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- Bulashova O
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- Burton C
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- Cabau Jr
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- Chauhan D
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- Chaussé I
- Chavada J
- Chaverra I
- Chaware G
- Chee L
- Chella S
- Chen Cp
- Chen J
- Chen Mh
- Chen Y
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- Cheng S
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- Cherlin R
- Cheung D
- Chhabra A
- Chintala P
- Chiodi L
- Choi Aj
- Chou S
- Chouinard G
- Christensen L
- Christenson S
- Chung A
- Churina S
- Cifkova R
- Ciglenecki N
- Cioffi A
- Cislowski D
- Cleveland T
- Clocotan M
- Cmrecnjak J
- Colfer H
- Colhoun H
- Collier D
- Collins R
- Coloma G
- Colquhoun D
- Colvin T
- Coman S
- Commerford P
- Commerford P
- Conrado Y
- Cools F
- Cornel Jh
- Corona V
- Coronel J
- Cosgrove N
- Cosgrove S
- Cosmi F
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- Coufalova Z
- Covell W
- Cox B
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- Craig W
- Crandall L
- Crawford G
- Crea F
- Crepps K
- Crocamo A
- Cromer M
- Cruz H
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- Csala L
- Cucher F
- Cuentas I
- Cuervo A
- Curiac D
- Cymerman K
- Cyprian R
- Czerski T
- D'Amours Dg
- D Dash
- D Dattani
- D Denham
- D Desai
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- D Digangi
- D Dunn
- Da Costa F
- Da Silva A
- Da Silva D Jr
- Da Silva O Jr
- Dahlen G
- Dalseg Am
- Damron M
- Danik J
- Davalos C
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- Davies N
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- Dawkins-Hughes S
- Dawood Sy
- Dayer M
- De Boer P
- De Caterina R
- De Jong C
- De Knijf K
- De Krumbach L
- De Los Milagros Had M
- De Los Rios M
- De Rosa S
- De Vos A
- De Wolf L
- Dean J
- Debnam S
- Decsi K
- Decsi Kl
- Dedek V
- Dedkova S
- Defosse C
- Degennaro N
- Dehning M
- Dela Llana A
- Delfonso F
- Delforge M
- Delgadillo T
- Dellasa M
- Dellborg M
- Dellorso M
- Demidova M
- Den Hartog F
- Denecke C
- Dengler T
- Dermitzakis A
- Deslongchamps F
- Dessalvi Cc
- Destro M
- Dettmer M
- Devasia T
- Deweerdt N
- Dhanak R
- Dhawan M
- Di Biase M
- Diago M
- Diaz M
- Dicken T
- Dickstein K
- Diederich C
- Diederich M
- Diehl R
- Diller P
- Dimattia M
- Dimitrov G
- Diodati J
- Dobariya H
- Dobilas V
- Dodds G
- Doesborg L
- Doggett J
- Dognini Gp
- Doi M
- Dokupilova A
- Dommerholt R
- Donahue K
- Donath M
- Donaubauer T
- Dong X
- Dormidontova G
- Dorogova I
- Dos Santos A
- Dos Santos F
- Dos Santos P
- Doughty A
- Doughty L
- Dovgalevskiy Y
- Dovgolis S
- Dragutksy B
- Dreese M
- Drost I
- Drouin K
- Duchesne L
- Duckert A
- Duda N
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- Dudhatra N
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- Dunhurst F
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- Dutka C
- Dwenger E
- Dzupina A
- Dékány Jn
- E Eleuteri
- E Englmann
- Earl J
- East C
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- Ebrahim I
- Eccleston D
- Echeverria L
- Eder F
- Edgerton L
- Edillo C
- Edwards J
- Edwards T
- Eichinger G
- Einhorn D
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- El Hachem M
- El Hafi S
- Ellenbroek D
- Ellis M
- Emil B
- Endo T
- Engelen W
- Erhard M
- Erickson B
- Ervin W
- Eskridge L
- Espinosa V
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- F Fedele
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- F Fucci
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- Faghih M
- Fail P
- Falcon D
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- Farias E
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- Fawson A
- Feitosa G
- Felario Junior Ga
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- Feng Y
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- Ferrari V
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- Ferraz R
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- Ferreira-Jardim A
- Fien E
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- Filho P
- Fintel D
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- Fischer Sm
- Fisher J
- Fitilev S
- Fitz-Patrick D
- Fitzpatrick L
- Flaksa I
- Flather M
- Flezar M
- Fliesser-Goerzer E
- Flores E
- Flores E
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- Flores H
- Floro T
- Foerster A
- Folkeringa Rj
- Fonseca A
- Fontaine S
- Forgon T
- Forgosh L
- Forker A
- Forster T
- Foster M
- Foucauld J
- Fowler V
- Fox B
- Franco M
- Francoeur L
- Frandsen B
- Frandsen B
- Frankenstein L
- Fratczak M
- Freitas E
- French J
- Frivold G
- Fruchter G
- Fu G
- Fucak E
- Fuchs R
- Fucili A
- Fukuike C
- Fullerton D
- Fulop P
- Fulop T
- Fulwani M
- Furch G
- Furuseth B
- G Gacioch
- G Gosselin
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- Gabor M
- Gabriel J
- Gabrielli D
- Gaeb-Strasas B
- Gamba C
- Ganau A
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- Garcia Duran R
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- Garner K
- Gazizianova V
- Gelb R
- Genest J
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- Gonsorcik J
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- Goudev A
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- Grover A
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- Gupta A
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- Gupta V
- Gutmann J
- Guzman I
- Guzman P
- Gwyn M
- Gyorgyova E
- H Haldane
- H Hansen
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- Haase F
- Haege R
- Haenel T
- Hage F
- Hageman T
- Hagemann D
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- Haidar A
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- Hegedus V
- Heider J
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- Henriksson A
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- Hiden C
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- Hinderaker P
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- Hirayama A
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- Hutchens E
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- T Tase
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- Talliard C
- Tamburrini P
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- Tan M
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- Taverner P
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- Teenan M
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- Teltser M
- Ten Holt W
- Terry K
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- Tesak M
- Teschner Ab
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- Vranckx P
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- Vuriya Ak
- W Wu
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- Wadell C
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- Waksman R
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- Walther I
- Walukiewicz P
- Wanderley Ff
- Wang Cp
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- Westberg Jc
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- White A
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- Wolf S
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- Woyczak D
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- Wyss F
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- Yamada T
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- Yamamoto H
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- Yao Z
- Yaoqing H
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- Yigit Z
- Yilmaz Mb
- Yim Kh
- Yim S
- Yokoyama M
- Yong H
- Yoshida M
- Yoshimoto E
- Yossen M
- Young A
- Younis L
- Youssef G
- Yuan Z
- Yunoki C
- Yupanqui H
- Z Zhai
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- Zadionchenko V
- Zadra R
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- Zdrenghea D
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- Zhang W
- Zhang Y
- Zhao R
- Zhou H
- Zidova M
- Zielinski M
- Zieve F
- Zineldine A.
- Zirlik A
- Zucchetti C
- Publication venue
- 'Massachusetts Medical Society'
- Publication date
- 01/01/2017
- Field of study
Background: Experimental and clinical data suggest that reducing inflammation without affecting lipid levels may reduce the risk of cardiovascular disease. Yet, the inflammatory hypothesis of atherothrombosis has remained unproved. Methods: We conducted a randomized, double-blind trial of canakinumab, a therapeutic monoclonal antibody targeting interleukin-1β, involving 10,061 patients with previous myocardial infarction and a high-sensitivity C-reactive protein level of 2 mg or more per liter. The trial compared three doses of canakinumab (50 mg, 150 mg, and 300 mg, administered subcutaneously every 3 months) with placebo. The primary efficacy end point was nonfatal myocardial infarction, nonfatal stroke, or cardiovascular death. RESULTS: At 48 months, the median reduction from baseline in the high-sensitivity C-reactive protein level was 26 percentage points greater in the group that received the 50-mg dose of canakinumab, 37 percentage points greater in the 150-mg group, and 41 percentage points greater in the 300-mg group than in the placebo group. Canakinumab did not reduce lipid levels from baseline. At a median follow-up of 3.7 years, the incidence rate for the primary end point was 4.50 events per 100 person-years in the placebo group, 4.11 events per 100 person-years in the 50-mg group, 3.86 events per 100 person-years in the 150-mg group, and 3.90 events per 100 person-years in the 300-mg group. The hazard ratios as compared with placebo were as follows: in the 50-mg group, 0.93 (95% confidence interval [CI], 0.80 to 1.07; P = 0.30); in the 150-mg group, 0.85 (95% CI, 0.74 to 0.98; P = 0.021); and in the 300-mg group, 0.86 (95% CI, 0.75 to 0.99; P = 0.031). The 150-mg dose, but not the other doses, met the prespecified multiplicity-adjusted threshold for statistical significance for the primary end point and the secondary end point that additionally included hospitalization for unstable angina that led to urgent revascularization (hazard ratio vs. placebo, 0.83; 95% CI, 0.73 to 0.95; P = 0.005). Canakinumab was associated with a higher incidence of fatal infection than was placebo. There was no significant difference in all-cause mortality (hazard ratio for all canakinumab doses vs. placebo, 0.94; 95% CI, 0.83 to 1.06; P = 0.31). Conclusions: Antiinflammatory therapy targeting the interleukin-1β innate immunity pathway with canakinumab at a dose of 150 mg every 3 months led to a significantly lower rate of recurrent cardiovascular events than placebo, independent of lipid-level lowering. (Funded by Novartis; CANTOS ClinicalTrials.gov number, NCT01327846.
Improvement of cerebral oxygenation patterns and metabolic validation of superselective intraarterial infusion of papaverine for the treatment of cerebral vasospasm
- Author
- Publication venue
- 'Journal of Neurosurgery Publishing Group (JNSPG)'
- Publication date
- Field of study
The clinical value of ceMRA versus DSA for follow-up of intracranial aneurysms treated by coil embolization: an assessment of occlusion classifications and impact on treatment decisions
- Author
- A Lecler
- A Rouchaud
- AJ Molyneux
- AJ Molyneux
- B Lubicz
- C Gramsch
- CJ Stapleton
- D Marciano
- D Roy
- HJ Cloft
- HJ Cloft
- J Menke
- JD Schaafsma
- JD Schaafsma
- JM Eskridge
- JR Mascitelli
- L Hacein-Bey
- L Pierot
- MJ van Amerongen
- N Lin
- ON Naggara
- P Lavoie
- PM Meyers
- R Agid
- RA Willinsky
- S Soize
- SL Zuckerman
- SP Ferns
- SU Ahmed
- TA Kuether
- TC Kwee
- TJ Kaufmann
- W Brinjikji
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Sol: An Agent-Based Framework for Cyber Situation Awareness
- Author
- A Byrski
- A Kaplan
- A Uszok
- A Uszok
- C MĂĽller-Schloer
- CF Smith
- CF Smith
- DL Still
- DL Still
- DT Moore
- FE Pollick
- G Cabri
- G Klein
- G Klein
- H Leibowitz
- J Bratman
- J Diggelen van
- J Diggelen van
- J Loyall
- JH Holland
- JM Bradshaw
- JM Bradshaw
- JM Bradshaw
- JR Bergen
- K Siddiqi
- KM Ford
- LA Temme
- LN Thibos
- M Carvalho
- M Carvalho
- M Carvalho
- M Carvalho
- M Carvalho
- M Carvalho
- M Lind
- N VanderHorn
- NE Johnson
- P Feltovich
- PJ Feltovich
- PJ Feltovich
- TC Eskridge
- X Yin
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
The Impact of Technology Upon In Situ Atmospheric Observations and Climate Science
- Author
- A Horvitz
- A Horvitz
- A Mahesh
- AT DeGaetano
- BE Schwartz
- BE Schwartz
- C Williams
- D Franklin
- D Franklin
- D Franklin
- DE Parker
- DJ Gaffen
- DJ Gaffen
- DJ Seidel
- DR Easterling
- DR Legates
- DR Legates
- F Guichard
- Federal Aviation Administration (FAA)
- Global Climate Observing System Steering Committee (GCOS-SC)
- Global Observing Systems Information Center (GOSIC)
- H Alexandersson
- H Tuomenvirta
- I Dune
- IV Chernykh
- JH Wang
- JK Angell
- JK Luers
- JN Lott
- JR Lanzante
- JR Lanzante
- KE Trenberth
- KT Redmond
- L Garand
- LA Vincent
- LF Bosart
- M Govett
- M New
- M New
- N Lott
- N Lott
- National Climatic Data Center (NCDC)
- National Climatic Data Center (NCDC)
- National Climatic Data Center (NCDC)
- National Climatic Data Center (NCDC)
- National Climatic Data Center (NCDC)
- National Climatic Data Center (NCDC)
- National Climatic Data Center (NCDC)
- National Climatic Data Center (NCDC)
- National Research Council (NRC)
- National Weather Service (NWS) Office of Operational Systems (OPS2)
- National Weather Service Office of Meteorology (NWS OM)
- NB Guttman
- Office of the Federal Coordinator for Meteorology (OFCM)
- P Zhai
- PD Jones
- PD Jones
- PD Jones
- PY Groisman
- PY Groisman
- R Lund
- RC Balling
- RD Butler
- RE Eskridge
- RG Quayle
- RJ Allen
- RL Slonaker
- RS Vose
- S Rosner
- T Peterson
- TC Peterson
- TC Peterson
- TR Karl
- TR Karl
- TR Karl
- TWR Wallis
- WP Elliott
- WP Elliott
- WP Elliott
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2004
- Field of study
Cerebral vasospasm in subarachnoid hemorrhage
- Author
- A Biondi
- A Egge
- A Ekelund
- AA Rabinstein
- AA Rabinstein
- Alejandro A. Rabinstein
- E Berendes
- EC Haley
- Eelco F. M. Wijdicks
- EF Wijdicks
- EH Brilstra
- G Wurm
- GK Bejjani
- H Hadeishi
- H Katoh
- H Otsubo
- J Gijn van
- J Hansen-Schwartz
- J Sen
- J Siironen
- JC Maroon
- JG Romano
- JI Suarez
- JM Eskridge
- JM Findlay
- JM Milburn
- JP Elliott
- JW Hop
- K Mori
- KF Lindegaard
- KT Kreiter
- L Feng
- L Lennihan
- M Shimoda
- MA Sloan
- ML Levy
- MM Treggiari
- MR Mayberg
- N Badjatia
- N Badjatia
- N Ross
- NF Kassell
- R Aaslid
- RC Heros
- RH Rosenwasser
- RP Kivisaari
- S Amin-Hanjani
- S Gasser
- SA Mayer
- SR Finfer
- TC Origitano
- V Aiyagari
- VL Feigin
- Y Kaku
- Y Roos
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Superficial temporal artery to middle cerebral artery bypass: past, present, and future
- Author
- Adams HP
- Amine ARC
- Barnett DW
- Broderick JP
- Burke JP
- Chater N
- Crowell RM
- Crowell RM
- Derdeyn CP
- Diaz FG
- Eguchi T
- Elliot JP
- Eskridge JM
- Gewertz BL
- Goda M
- Grote E
- Grubb RL
- Hadley MN
- Hirano T
- Holbach KH
- Hopkins LN
- Houkin K
- Ikezaki K
- Jacobson JH
- Javedan SP
- Kawagushi S
- Klijn CJM
- Kobayashi H
- Kodama N
- KrayenbĂĽhl HA
- Krishnamurthy S
- Kuroda S
- Latchaw RE
- Linskey ME
- Miller JD
- Morimoto M
- Neff KW
- Newell DW
- Origitano TC
- Peerless SJ
- Peerless SL
- Pikus HJ
- Powers WJ
- Powers WJ
- Roski RA
- Røhl L
- Sakamoto K
- Samson DS
- Schaefer PW
- Schaps P
- Sobesky J
- Spetzler RF
- Spetzler RF
- Spetzler RF
- Spetzler RF
- Spetzler RF
- Sugawara Y
- Sundt TM
- Swearingen B
- Tew JM
- Tsuda Y
- Walker BS
- Whisnant JP
- Woringer E
- YaĹźargil MG
- YaĹźargil MG
- YaĹźargil MG
- Zumstein B
- Publication venue
- 'Journal of Neurosurgery Publishing Group (JNSPG)'
- Publication date
- Field of study
Attitudes of Future Doctors Towards LGBT Patients in Conservative Malaysian Society
- Author
- A Crockett
- A De Rycker
- A Hu
- A Kar
- AD Ong
- Alexander Lourdes Samy
- Andrew L. S. Foong
- AW Hughes
- BB Zikmund
- C Hirschman
- C Pereira
- CG Ng
- CK Wilson
- CS Levine
- D Lakens
- DN Ruble
- DT McDermott
- E Senel
- E Sri
- EC Westgate
- EGCF Chai
- EJ Manalastas
- F Idris
- FS Lai
- G Misra
- G Spiliotopoulou
- GK Brown
- GP Beehler
- H Vera
- HJ Liu
- HY Kim
- I Ajzen
- J Gerhards
- J Stark
- J-P Leyens
- JB Carroll
- JD Brown
- JJ Barnette
- JL Neo
- JN Goh
- Jun Wei Liow
- JW Liow
- K Rossman
- K Slootmaeckers
- KM Zosuls
- KP Lee
- L Roggemans
- LA Samovar
- LL Thurstone
- LS Kao
- M Fishbein
- M Reece
- MAM Adil
- MD Barr
- MS Felix
- MW Ross
- N Subhi
- NF Sanchez
- OA Chuah
- R Cover
- RL Kitts
- RM Young
- RSK Chan
- RT Liu
- S Ahmadi
- S Asthana
- S Jäckle
- S Nagaraj
- S Sahni
- S Seguino
- SA Matondang
- SH Lim
- Sivalingam Nalliah
- SJ Hunt
- SK Gill
- T Buchmueller
- T Maniam
- TC Souza
- TK Ahrold
- V Sinha
- W Blanton
- Wah Yun Low
- WL Williams
- WN Eskridge
- WNW Husin
- WY Low
- Y Xie
- Zahra Fazli Khalaf
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study