Guruku sayang, guruku berkembang: Problem mapping model dalam proses pengembangan pendidikan anak usia dini (PAUD)

Early Childhood Education Development (or PAUD in Indonesian) is essential in today’s world. A participative action research (PAR) approach was one of the actions done to support the development. One important stage in PAR is the preliminary study stage. The focus of this research is to know how the preliminary study was done in the perspective of problem mapping. The data collection techniques are performed with observations, surveys, documents, and interviews. This research produces a problem mapping model that is important in determining the problem that is used as the main agenda of mentoring to fit the needs of assistance by community priorities. The problem mapping model includes several stages: problem surveying and capturing, problem displaying, problem valuing, problem clustering, and a stage to determines the main problem for the action plan or the completion process

Important Factors to Remember when Constructing a Cross-site Scripting Prevention Mechanism

Web application has become an essential part of daily activities to provide easy accessibility that ensures better performance. It is a platform where sensitive information such as username, password, credit card details, operating system and software version etc. is stored that attracts intruders to generate most of their attacks. Intruders can steal valuable data by compromising web application security flaws; Cross Site Scripting (XSS) vulnerability is one of these. Several studies have been conducted in order to prevent the XSS vulnerability. In this research, we searched Scopus Indexed articles published in the last 11 years (between 2008 and 2020) using two keywords (“XSS Attack Prevention” and “XSS Prevention”). The purpose of this study was to conduct a literature review on XSS prevention techniques e.g. strengths and weaknesses, including structural issues and real-time deployment location in order to extract valuable information. This review identified 14 articles among the 25 selected articles that provided various suitable prevention techniques for XSS attacks. Seven articles are based on tools that have been implemented and take into account design, coding, testing, and integrating validation processes, six articles are about server site solutions, and one is about automatic mitigation solutions. As a result, this research will be invaluable in guiding the advancement of XSS prevention techniques

Abnormal prenatal brain development in Chiari II malformation

IntroductionThe Chiari II is a relatively common birth defect that is associated with open spinal abnormalities and is characterized by caudal migration of the posterior fossa contents through the foramen magnum. The pathophysiology of Chiari II is not entirely known, and the neurobiological substrate beyond posterior fossa findings remains unexplored. We aimed to identify brain regions altered in Chiari II fetuses between 17 and 26 GW.MethodsWe used in vivo structural T2-weighted MRIs of 31 fetuses (6 controls and 25 cases with Chiari II).ResultsThe results of our study indicated altered development of diencephalon and proliferative zones (ventricular and subventricular zones) in fetuses with a Chiari II malformation compared to controls. Specifically, fetuses with Chiari II showed significantly smaller volumes of the diencephalon and significantly larger volumes of lateral ventricles and proliferative zones.DiscussionWe conclude that regional brain development should be taken into consideration when evaluating prenatal brain development in fetuses with Chiari II

Relatório de estágio em farmácia comunitária

Relatório de estágio realizado no âmbito do Mestrado Integrado em Ciências Farmacêuticas, apresentado à Faculdade de Farmácia da Universidade de Coimbr

Staphylococcal Protein A with Engineered Cysteine: Comparison of Monomeric Content as a Critical Quality Attribute during Intracellular and Extracellular Expression

Background: The introduction of engineered cysteine in staphylococcal protein A (SPA-cys) for site-specific conjugation results in a substantial amount of dimerized SPA due to spontaneous oxidation during its production, leading to inaccessibility and thus rendering it unusable. Monomers are usually recovered from dimers by using reducing agents before conjugation in subsequent steps. However, this leads to low conjugation efficiency and increases overall cost and production time. This study aims to systematically compare and quantify the monomeric and dimeric content of SPA when produced through intracellular and extracellular routes in E. coli. Methods: Purified SPAs with and without cysteine from both intracellular and extracellular processes are compared for their monomeric content and efficiency to conjugate on solid support matrix with and without an additional pre-step of reduction. Results: The monomeric form of SPA-cys, which is a desired key quality attribute, is less than 50% when produced extracellularly. SPA-cys produced through the intracellular production process has high monomeric content (≥85%) and shows higher binding to solid support. Conclusion: The study demonstrates that the intracellular route for production of SPA-cys should be the preferred method, and the release assays for SPA-cys products should include the amount of monomeric content as one of the quality attributes. The abundance of monomeric content enhances the site-specific conjugation efficiency and density of SPA on the resin matrix

Inovasi Slurry Ice Machine Indonesia/Mesin Pembuat Bubur Es (MPBE) Merah Putih Metode Scraped-Surface Berkapasitas 1,5 dan 0,5 Ton/Hari: Innovation of Indonesian Scraped-Surface Slurry Ice Machine with 1.5 and 0.5 Ton Per Day Capacity

Rekayasa terhadap evaporator, kondensor, dan sistem kontrol elektronik telah dilakukan untuk menghasilkan inovasi sebuah unit slurry ice machine/mesin pembuat bubur es (MPBE) yang dioperasikan dengan tenaga listrik 3 phase. Penelitian ini bertujuan untuk menghasilkan mesin pembuatan bubur es yang ramah lingkungan. Metode pembuatan dilakukan dengan menggunakan desain yang dibuat oleh PT Hikari Solusino Sukses dengan kapasitas masing-masing 0,5 dan 1,5 ton/hari . Hasil menunjukkan bahwa MPBE dapat mulai memproduksi bubur es sekitar 2 menit dengan kapasitas produksi 1.500 kg bubur es dalam 24 jam. Untuk memenuhi kebutuhan konsumen telah diproduksi unit MPBE berkapasitas 1.500 kg/24 jam yang dioperasikan dengan motor berbahan bakar solar dan berkapasitas 500 kg/24 jam yang dioperasikan dengan motor berbahan bakar bensin. Dibandingkan dengan unit prototipe MPBE yang telah dibuat dan unit yang dijual di pasar internasional, inovasi unit MPBE ini dapat memproduksi bubur es lebih cepat, yaitu 2 menit berbanding 20-30 menit, serta fraksi bubur es yang tinggi, hingga 90% dibandingkan 30-40%. Berdasarkan nilai lebih pada kualitas bubur es yang diproduksi, variasi pengoperasian menggunakan motor penggerak berbahan bakar bensin dan solar, serta dukungan ekosistem manufaktur di Indonesia, inovasi MPBE ini diyakini dapat diproduksi secara komersial karena harga dan kualitasnya yang kompetitif.Designing evaporator, condensor and electronic control were conducted to produce an innovation of slurry ice machine operated by 3-phase electricity. Result indicated that the machine start producing slurry ice within about 2 minutes, with capacity of 1,500 kg/24 hours and slurry ice crystal fraction about 90%. Based on consumer request, two slurry ice machine has ben made. The first one was a 1,500 kg/24 hours operated by diesel engine, while the second was a 500 kg/24 hours slurry ice machine operated by gasoline engine. Compared to the prototype unit and machine available in the commercial market, the innovation unit start producing slurry ice much faster, 2 minutes vs 20-30 minutes, and produce fraction of slurry ice crystal much higher, 90% vs 30-40%. Due to its superior quality, the practical mode of operation both by diesel oil and gasoline, and supported by ecosystem manufacture available in Indonesia, it is prospective to produce the slurry ice machine commercially

Characterizing of heavy metal accumulation, translocation and yield response traits of Chenopodium quinoa

Heavy metal contamination in soil is a major environmental threat that reduces crop productivity. Quinoa as a phytoremediation potential is a viable option to mitigate the effect of heavy metal stress. This study aimed to investigate the phytoremediation characteristics of four quinoa lines when exposed to soil contaminated with heavy metal. Four quinoa lines (A1, A2, A7, and A9) were allowed to grow in three fields (control (UAF), Chakera farm (UAF), and Chakera village) under RCBD split plot arrangement with three replication. Maximum seed yield (4100 kg ha−1) was obtained by A7 which was statistically similar to the A2 line (3648 kg ha−1) obtained from Chakera Farm (UAF) having sewage water application. While low yield was obtained from A9 (1482 kg ha−1) in normal soil (control). Both A7 and A2 lines exhibited higher biomass and seed yield at three fields. Both fields having sewage water application resulted in higher growth and superb seed yield of quinoa lines as compared to the control. Quinoa lines (A2 and A7) attained (51 and 43%) high seed yield at Chakera farm (UAF) having sewage water application in comparison to control having normal irrigation. Seed quality was substantially affected by heavy metal concentration in both contaminated fields. Metals concentration determined in seed samples of A7 was high as compared to A2. Hence A2 may be said a nutritionally superior quinoa line as metal levels were within the permissible level set by FAO/WHO

Falsafah pendidikan Ulul Albab: Pengembangan kurikulum berbasis KKNI dan SNPT UIN Maulana Malik Ibrahim Malang

Buku Falsafah Pendidikan Ulul Albab ini merupakan pengembangan lebih lanjut dari pemikiran pengembangan kurikulum yang selama ini telah dirumuskan oleh UIN Maulana Malik Ibrahim Malang sejak kampus ini berubah menjadi Universitas. Berisi gagasan dan pemikiran tentang integrasi keilmuan dan standar kompetensi lulusan yang telah dirancang oleh para pemikir pendahulu seperti Prof. Dr. H. Imam Suprayogo, Prof. H. Muhaimin, MA., Prof. Dr. Mudjia Rahardjo, M.Si. dan para pemikir pengembangan keilmuan di UIN Maulana Malik Ibrahim Malang lainnya yang tidak dapat disebutkan satu persatu. Pikiran-pikiran para pendahulu yang masih relevan tetap kita jadikan dasar dan rujukan untuk disesuaikan dengan perkembangan dan kebutuhan yang ada serta untuk memenuhi tuntutan terbitnya peraturan-peraturan baru. Apa yang dilakukan ini tidak lain merupakan bentuk al-Muhafadzah ala al-qadim al-shalih wa al-akhzu bi al-jadid alashlah