Escoliosis congénitas causadas por hemivertebras

Presentamos un estudio retrospectivo de 26 pacientes diagnosticados de escoliosis congénitas causadas por hemivertebras, liemos analizado la evolución de las curvas según el tipo de hemivértebra, su localización y el tratamiento recibido. Se han obtenido los peores resultados en las niñas, cuando el diagnóstico se realizó después de los 10 años de edad, en las curvas localizadas en la región toracolumbar, en las hemivértebras múltiples y, dentro de ellas, en las unilaterales segmentadas no adyacentes y en los pacientes tratados ortopédicamente.A retrospective study of 26 patients with congenital scoliosis due to hemivertebra was conducted. Curve progression was analysed regarding the type of hemivertebra, its localization, and the applied treatment. The worst results were found in girls, in cases who were diagnosed with more than to years of age, in thoraco-lumbar curves, in multiple hemivertebra, especially in non-adjacent segmented unilateral hemivertebra and, finally, in patients treated with orthopaedic methods

Children's consumption of rabbit meat

[EN] The nutritional and dietary properties of rabbit meat make it an ideal food for children, recommended by the World Health Organisation. However, the presence of children under 18 in the home has been found to decrease the frequency of rabbit meat consumption. If we focus on households with children under 18, 52.5% of minors do not consume rabbit meat. The main reason why children (intended as people under 18 yr old) do not consume rabbit meat is the fact that they do not like it (40.9%) and because it is not bought/eaten at home (30.9%). Faced with this situation, there is a pressing need to seek appropriate strategies to adapt rabbit meat for consumption by the youngest family members. In light of the results, the following strategies are proposed. First, the development of functional foods for babies and children, such as rabbit meat enriched with ω3 and docosahexaenoic acid. Secondly, improving meat tenderness. Third, adapting rabbit meat presentations for children (burgers, nuggets, sausages, marinades …), converting them into convenience products for parents and extending their shelf life. Fourth, adapting the labelling/packaging for children to attract attention of both parents and offspring. Finally, developing communication strategies on the nutritional value of rabbit meat aimed at both children and parents. It is observed that if minors consume rabbit meat, they also eat other types of meat such as lamb and beef more often. Therefore, in this type of households a varied and complete diet is consumed in terms of meat consumption, so it would be necessary to rethink joint communication strategies among the three meat sectors. Promoting rabbit meat consumption among the under 18s has several consequences, as in the future they will be in charge of household purchases or share this responsibility.Escribá-Pérez, C.; Baviera-Puig, A.; Montero-Vicente, L.; Buitrago-Vera, J. (2019). 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World Rabbit Sci., 20: 155-162. https://doi.org/10.4995/wrs.2012.1147González-Redondo P., Mena Y., Fernández-Cabanás V.M. 2010. Factors affecting rabbit meat consumption among Spanish university students. Ecol. Food Nutr., 49: 298-315. https://doi.org/10.1080/03670244.2010.491053Halford J.C.G., Gillespie J., Brown V., Pontin E.E., Dovey T.M. 2004. Effect of television advertisements for foods on food consumption in children. Appetite, 42: 221-225. https://doi.org/10.1016/j.appet.2003.11.006Hermida M., González M., Miranda M., Rodríguez-Otero J.L. 2006. Mineral analysis in rabbit meat from Galicia (NW Spain). Meat Sci., 73: 635-639. https://doi.org/10.1016/j.meatsci.2006.03.004Hernández P. 2008. Enhancement of nutritional quality and safety in rabbit meat. In Proc.: 9th World Rabbit Congress, 10-13 June, 2008. Verona, Italy. 1: 1287-1300.Ilicic J., Baxter S.M., Kulczynski A. 2018. To Meet or Meat? Homophones in Advertising Encourage Judgments and Behaviors in Children. J. 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Modifications of fatty acids profile, lipid peroxidation and antioxidant capacity in raw and cooked rabbit burgers added with ginger. Meat Sci., 133: 151-158. https://doi.org/10.1016/j.meatsci.2017.07.003MAPAMA. 2018. Informe del consumo de alimentación en España 2017. Ministerio de Agricultura, Pesca y Alimentación. Available at: https://www.mapa.gob.es/images/es/informeanualdeconsumoalimentario2017_tcm30-456186.pdf. Accessed May 2019.Montero-Vicente L., Escribá-Pérez C., Baviera-Puig A., Buitrago-Vera J. 2018. Analysis of the commercial value of rabbit meat based on positioning of the different types of fresh meat. Span. J. Agric. Res., 16: e0110. https://doi.org/10.5424/sjar/2018163-13407Morgan J., Taylor A., Fewtrell M. 2004. Meat Consumption is Positively Associated with Psychomotor Outcome in Children up to 24 Months of Age. J. Pediatr. Gastroenterol. Nutr., 39: 493-498. https://doi.org/10.1097/00005176-200411000-00009Neumann C.G., Murphy S.P., Gewa C., Grillenberger M., Bwibo N.O. 2007. Meat Supplementation Improves Growth, Cognitive, and Behavioral Outcomes in Kenyan Children. J. Nutr., 137: 1119-1123. https://doi.org/10.1093/jn/137.4.1119Nistor E., Bampidis V.A., Păcală N., Pentea M., Tozer J., Prundeanu, H. 2013. Nutrient Content of Rabbit Meat as Compared to Chicken, Beef and Pork Meat. J. Anim. Prod. Adv., 3: 172-176. https://doi.org/10.5455/japa.20130411110313Patrick H., Nicklas T.A., Hughes S.O., Morales M. 2005. The benefits of authoritative feeding style: caregiver feeding styles and children's food consumption patterns. Appetite, 44: 243-249. https://doi.org/10.1016/j.appet.2002.07.001Petracci M., Cavani C. 2013. Rabbit meat processing: historical perspective to future directions. World Rabbit Sci., 21: 217-226. https://doi.org/10.4995/wrs.2013.1329Petracci M., Soglia F., Leroy F. 2018. Rabbit meat in need of a hattrick: from tradition to innovation (and back). Meat Sci., 146: 93-100. https://doi.org/10.1016/j.meatsci.2018.08.003Petrescu D., Petrescu-Mag R. 2018. Consumer behaviour related to rabbit meat as functional food. World Rabbit Sci., 26: 321-333. https://doi.org/10.4995/wrs.2018.10435Pla M., Guerrero L., Guardia D., Oliver M.A., Blasco A. 1998. Carcass characteristics and meat quality of rabbit lines selected for different objectives: I. Between lines comparison. Livest. Prod. Sci., 54: 115-123. https://doi.org/10.1016/s0301-6226(97)00179-6Santesmases, M. 1996. Términos de marketing: Diccionario - Base de datos. Ediciones Pirámide, Madrid, Spain.Soglia F., Petracci M., Mudalal S., Vannini L., Gozzi G., Camprini L., Cavani C. 2014. Partial replacement of sodium chloride with potassium chloride in marinated rabbit meat. Int. J. Food Sci. 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Prototype of a high resolution regional reanalysis for Iberian Peninsula an Balearic Islands (IBERA)

Póster presentado en: 1st ACCORD All Staff Workshop celebrado del 12 al 16 de abril de 2021 de forma online

Difficult tracheal intubation in neonates and infants. NEonate and Children audiT of Anaesthesia pRactice IN Europe (NECTARINE): a prospective European multicentre observational study

BACKGROUND: Neonates and infants are susceptible to hypoxaemia in the perioperative period. The aim of this study was to analyse interventions related to anaesthesia tracheal intubations in this European cohort and identify their clinical consequences. METHODS: We performed a secondary analysis of tracheal intubations of the European multicentre observational trial (NEonate and Children audiT of Anaesthesia pRactice IN Europe [NECTARINE]) in neonates and small infants with difficult tracheal intubation. The primary endpoint was the incidence of difficult intubation and the related complications. The secondary endpoints were the risk factors for severe hypoxaemia attributed to difficult airway management, and 30 and 90 day outcomes. RESULTS: Tracheal intubation was planned in 4683 procedures. Difficult tracheal intubation, defined as two failed attempts of direct laryngoscopy, occurred in 266 children (271 procedures) with an incidence (95% confidence interval [CI]) of 5.8% (95% CI, 5.1–6.5). Bradycardia occurred in 8% of the cases with difficult intubation, whereas a significant decrease in oxygen saturation (SpO2<90% for 60 s) was reported in 40%. No associated risk factors could be identified among co-morbidities, surgical, or anaesthesia management. Using propensity scoring to adjust for confounders, difficult anaesthesia tracheal intubation did not lead to an increase in 30 and 90 day morbidity or mortality. CONCLUSIONS: The results of the present study demonstrate a high incidence of difficult tracheal intubation in children less than 60 weeks post-conceptual age commonly resulting in severe hypoxaemia. Reassuringly, the morbidity and mortality at 30 and 90 days was not increased by the occurrence of a difficult intubation event

A922 Sequential measurement of 1 hour creatinine clearance (1-CRCL) in critically ill patients at risk of acute kidney injury (AKI)

Meeting abstrac

Peri-operative red blood cell transfusion in neonates and infants: NEonate and Children audiT of Anaesthesia pRactice IN Europe: A prospective European multicentre observational study

BACKGROUND: Little is known about current clinical practice concerning peri-operative red blood cell transfusion in neonates and small infants. Guidelines suggest transfusions based on haemoglobin thresholds ranging from 8.5 to 12 g dl-1, distinguishing between children from birth to day 7 (week 1), from day 8 to day 14 (week 2) or from day 15 (≥week 3) onwards. OBJECTIVE: To observe peri-operative red blood cell transfusion practice according to guidelines in relation to patient outcome. DESIGN: A multicentre observational study. SETTING: The NEonate-Children sTudy of Anaesthesia pRactice IN Europe (NECTARINE) trial recruited patients up to 60 weeks' postmenstrual age undergoing anaesthesia for surgical or diagnostic procedures from 165 centres in 31 European countries between March 2016 and January 2017. PATIENTS: The data included 5609 patients undergoing 6542 procedures. Inclusion criteria was a peri-operative red blood cell transfusion. MAIN OUTCOME MEASURES: The primary endpoint was the haemoglobin level triggering a transfusion for neonates in week 1, week 2 and week 3. Secondary endpoints were transfusion volumes, 'delta haemoglobin' (preprocedure - transfusion-triggering) and 30-day and 90-day morbidity and mortality. RESULTS: Peri-operative red blood cell transfusions were recorded during 447 procedures (6.9%). The median haemoglobin levels triggering a transfusion were 9.6 [IQR 8.7 to 10.9] g dl-1 for neonates in week 1, 9.6 [7.7 to 10.4] g dl-1 in week 2 and 8.0 [7.3 to 9.0] g dl-1 in week 3. The median transfusion volume was 17.1 [11.1 to 26.4] ml kg-1 with a median delta haemoglobin of 1.8 [0.0 to 3.6] g dl-1. Thirty-day morbidity was 47.8% with an overall mortality of 11.3%. CONCLUSIONS: Results indicate lower transfusion-triggering haemoglobin thresholds in clinical practice than suggested by current guidelines. The high morbidity and mortality of this NECTARINE sub-cohort calls for investigative action and evidence-based guidelines addressing peri-operative red blood cell transfusions strategies. TRIAL REGISTRATION: ClinicalTrials.gov, identifier: NCT02350348

El equipo Valencia-iGEM diseña y construye la primera pantalla biológica

Los autores agradecen el apoyo recibido de las entidades financiadoras, destacando el Proyecto i-MATH (FUT-C4-0181: Participación española en iGEM: el papel de la modelización matemática en el emergente campo multidisciplinar de la Biología Sintética); el Vicerrectorado de Investigación de la UPV; el proyecto europeo TarPol (FP7/2007/212894); el Institut Cavanilles de la UV; y el IUMPA y la ETSII de la UPV. Finalmente, agradecen encarecidamente la labor de Pilar Aliaga y Minerva Báguena.Pitarch, M.; Crespo, J.; Hueso, A.; Marco, G.; Otero, E.; Palanca, C.; Rivera, S.... (2010). El equipo Valencia-iGEM diseña y construye la primera pantalla biológica. Matematicalia. 6(3):1-5. http://hdl.handle.net/10251/151307S156