Fujimori gate flap: an old flap for reconstruction of lower lip defects due to lower lip carcinoma resection

PubMed: 25010804OBJECTIVES: This study aims to present our clinic experiences on the Fujimori gate flap used for reconstruction of lower lip defect due to lower lip carcinoma.PATIENTS AND METHODS: This retrospective study included 19 patients (7 females, 12 males; mean age 60.3 years; range 41 to 79 years) who underwent reconstruction with the Fujimori-gate flap between January 2006 and March 2011. Demographic features of all patients and postoperative long-term functional and aesthetic results were reviewed.RESULTS: The mean size of the defects was 34.2 mm (range, 10 to 60 mm). Totally 27 flaps were elevated. No complication was observed after surgical procedure. In the long-term, nine patients underwent minor revisions. None of the patients showed local recurrence.CONCLUSION: Fujimori gate flap may be used for the reconstruction of the soft tissue loss after tumor surgery at lower lip

A Comparison of the Maximal Fat Oxidation Rates of Three Different Time Periods in The Fatmax Stage

This study aimed to compare the maximal fat oxidation (MFO) rates obtained from the stage average, last 2 min average, and highest value in the Fatmax stage determined with a 6 min step protocol. A total of 35 overweight, sedentary healthy men (age: 25.4 ± 0.7 years, body mass index: 26.0 ± 0.6 kg/m2) participated in the study. Substrate oxidation was calculated using breath-by-breath gas exchange data for each stage. When the change in the fat oxidation rate for every min throughout the Fatmax stage was evaluated, the average value of the 4th min was significantly lower than that of the 2nd and 3rd min (p < 0.01). In addition, the 5th and 6th min fat oxidation rates were significantly lower than the rates of the 1st, 2nd, 3rd, and 4th min (0.30 ± 0.01 and 0.29 ± 0.01 g/min for the 5th and 6th min, respectively, vs. 0.35 ± 0.02, 0.34 ± 0.02, 0.33 ± 0.02, and 0.31 ± 0.01 g/min for the 1st, 2nd, 3rd, and 4th min, respectively; p < 0.01). Most of the participants had MFO rates in the 1st min of the stage (16/35 participants), and the MFO rates of the remaining participants were observed in the 2nd, 3rd, and 4th min (7/35, 4/35, and 8/35 participants, respectively). None of the participants had MFO rates in the 5th or 6th min. The individual MFO rate (highest fat oxidation rate during Fatmax) was significantly higher than the fat oxidation rate calculated with the last 2 min average values (0.36 ± 0.02 and 0.30 ± 0.01 g/min, respectively; p < 0.05). In conclusion, the calculation of the fat oxidation rate by averaging the last portion of the Fatmax stage data may cause the underestimation of the MFO rate, which probably occurs earlier in the Fatmax stage

Evaluation of the interaction between proliferation, oxidant–antioxidant status, Wnt pathway, and apoptosis in zebrafish embryos exposed to silver nanoparticles used in textile industry

WOS: 000419943200015PubMed ID: 29283201Antimicrobial textile products are developing rapidly as an important part of functional textiles. Silver nanoparticles (AgNPs) are nanotechnology products with antimicrobial properties. However, exposure to nanoparticles in daily life is an important issue for public health, still being updated. Aim was to evaluate the effects of AgNPs on the development of zebrafish embryos focusing on Wnt pathway, proliferation, oxidant-antioxidant status, and apoptosis. The expressions of ccnd1 and gsk3 beta were determined by RT-PCR, whereas beta-catenin and proliferative cell antigen (PCNA) expressions were determined immunohistochemically. Lipid peroxidation, superoxide dismutase, and glutathione-S-transferase activities were determined spectrophotometrically. Apoptosis was determined using acridine orange staining. Oxidant status, apoptosis, immunohistochemical PCNA, and beta-catenin staining increased, whereas ccnd1 and antioxidant enzyme activities decreased in AgNPs-exposed embryos in a dose-dependent manner. Our results indicate the interaction of possible mechanisms that may be responsible for the toxic effects of AgNPs in zebrafish embryos

Comparision Of Young National And TOPC Team Female Swimmers’ Front Crawl Swimming Performance With Underwater Analysis

B u çalışmanın amacı, genç yüzme milli takımı ve Türkiye Olimpiyat Hazırlık Merkezi (TOHM) Projesi kapsamındaki Adana yüzme takımından yüzücülerin sualtı görüntüleme sistemi ile kulaç karakteristiklerinin incelenmesi ve 50 m. serbest yüzme performans verilerinin karşılaştırılmasıdır. Milli takımdan 8 ve TOHM takımından 8 olmak üzere toplam 16 yarışmacı genç kadın yüzücü çalışmamıza katılmıştır. Antropometrik ve derialtı yağ doku ölçümleri yapılarak kas ve yağ oranları ile beden kütle endeksleri (BKİ) hesaplanmıştır. 50 m. serbest yüzme kulaç karakteristikleri, sualtı hareketli kamera sistemi ile kaydedilmiştir. Hız, süre, Kulaç Sayısı (KS), Kulaç Oranı (KO), Kulaç Uzunluğu (KU) ve Kulaç İndeksi (Kİ) verileri, sualtı analiz programı ile incelenmiştir. İstatistiksel analiz SPSS-V21 programı kullanılarak bağımsız t testi ve Mann Whittney U testi ile p0,05). Milli yüzücüler, TOHM sporcuları ile karşılaştırıldıklarında anlamlı olarak daha kaslı, daha ağır ve daha geniş kol açıklığı ölçüm değerlerine sahip bulunmuşlardır (p0,05). Milli yüzücülerin 50 metre yüzme dereceleri ile Kİ (r = -0,89) verileri arasında istatistiksel olarak anlamlı bir ilişki tespit edilmişken, TOHM takımında bu ilişkiye rastlanmamıştır (p>0,05). Çalışmamızın sonuçlarına göre; kadın yüzücülerin kulaç karakteristiğini ifade eden verilerin tanımlanması, incelenmesi ve iyileştirilmesinin, performansın geliştirilmesi adına büyük önem taşıdığı düşünülmektedir. Benzer gruplarda, uzun dönemde performansın elit seviyeye taşınmasının, yüzücülerin KU, Kİ ve bunlara bağlı olarak yüzme tekniğinin geliştirilmesiyle mümkün olabileceği düşünülmektedirThe aim of the present study is to compare swimming stroke characteristics of young national Olympic swimmers and swimmers from Olympic Preparation Centers of Turkey in Adana (TOPC) by using underwater video record system. Anthropometric and skinfold thicknesses of the swimmers’ were measured. Body fat and body mass indexes were calculated. 50m front crawl swimming performances were recorded with an Underwater Moving Camera System. Statistical analysis procedures were carried out by using SPSS-V21 software with Independent Samples t-Test and Mann Whittney-U test. The significance level was accepted as p0,05). Body mass, arm span, mesomorph, muscle and bone percentage of national swimmers were found significantly higher than TOPC swimmers (p0,05). The results of our study show that defining the data expressing female swimmers’ stroke characteristics and analysis have great importance to improve swimming performance. We posit that developing stroke length, stroke index and consequently swimming techniques are essential to achieve elite-level performance improvement in the long term