A Review of the Prevention and Treatment of Hypertrophic Scars: Part I Clinical Aspects

The therapeutic management of hypertrophic scars remains challenging. Numerous methods have been described for the treatment of hypertrophic scars but, to date, the optimal treatment method has not been established. The aim of this review is to discuss the therapeutic modalities in the light of current literature, and to guide regarding the choice of treatment methods for physicians. The surgical and non-surgical treatment and prevention methods of the hypertrophic scars were reviewed and some recommendations for physicians who try to treat or prevent the hypertrophic scar were developed under cover of current literature and our personal experiences. A lot of therapeutic modalities have been described for the hypertrophic scars so far, but there is no absolute curative method alone. The most appropriate method or methods should be selected according to the patient and #8217;s needs and properties of the scar. The therapists can benefit from our review when they select the most appropriate method or methods for treatment of hypertrophic scars. [Arch Clin Exp Surg 2012; 1(4.000): 237-248

A Review of the Prevention and Treatment of Hypertrophic Scars: Part II. Experimental Studies

The understanding of the pathophysiological events of wound healing is very important to carry out the prevention or treatment of hypertrophic scars. Wound healing is a complex process consisting of the overlapping events, and the researchers have focused on the pathophysiology of the scar formation. The purpose of this article is to review the recent experimental studies about hypertrophic scars, and to analyze the substances focused on by recent experimental studies. We analyzed the researches for new hopeful treatment modalities as well as the substances that are important to wound healing in the second part of this extensive review. The researchers have tried to find a way to scarless wound healing, and it seems likely that new therapies will be available within the next few years. [Arch Clin Exp Surg 2013; 2(1.000): 49-58

The Effect of Subcutaneous Mesenchymal Stem Cell Injection on Statis Zone and Apoptosis in an Experimental Burn Model

Background: In an acute burn injury the zone of stasis is initially vital but may progress to coagulation necrosis with time. In this study, salvage of the zone of stasis was aimed at by subcutaneous mesenchymal stem cell injection

Comparison of silver-coated dressing (Acticoat (R)), chlorhexidine acetate 0.5% (Bactigrass (R)) and nystatin for topical antifungal effect in Candida albicans-contaminated, full-skin-thickness rat burn wounds

Background: In this experimental animal study, the effects of three different topical antimicrobial dressings on Candida albicans contaminated full-thickness burn in rats were analyzed