513 research outputs found
Simulation of Atomic Structure Near Nanovoids in BCC Iron
Generally, displacement fields near voids are determined by the equations of elasticity theory. Such a description has its disadvantages as it does not take into account the discrete atomic structure of materials. In this work, we use a new variant of Molecular Static method for investigation of the atomic structure near nanovoids. In our model an iterative procedure is employed, in which the atomic structure in the void vicinity and the parameter determining the displacement of atoms embedded into an elastic continuum are obtained in a self-consistent manner. Results show that the displacements are significantly different for varies crystallographic directions.
Keywords: voids; iron; simulation; atomic structure; vacancie
Comparison of expenditure of using experimental models of carcinogenesis
Despite significant advances in the diagnosis and treatment of oncopathology, the main epidemic indicators have a negative trend.Based on the above, a very relevant topic is the development of experimental models of carcinogenesis. The importance of scientific work in this area is increasing because in experimental conditions it is better to test new methods, diagnostics and treatment. Thus, it becomes possible to study the peculiarities of the pathogenesis of any tumor at different stages.The purpose of the work – to study and demonstrate the strengths and weaknesses of the main experimental models of carcinogenesis for further selection of the most appropriate.Results The main directions of carcinogenesis modeling are presented in the article. Initially, the problem was justified. The next step is described in chronological order of using the models.Of course, the achievements of clinical and experimental oncology played an important role in the emergence of models. Thus, the first model was the effect of physical and chemical carcinogens on a laboratory animal. The latest achievement of experimental oncology is the use of stem cells in combination with genetic engineering.No less important is the fact of comparing experimental models. We present the strengths and weaknesses of all these models.Conclusions1. To date, there are a large number of experimental models of carcinogenesis.2. When planning a study, you need to calculate all the goals to be achieved and select the appropriate model.3. The most effective and common model for ascites ovarian tumor is the transplantation of atypical cells to laboratory animals
Economic factors of increasing fertility in the Volga Federal District: a retrospective analysis (2000–2020)
Purpose: to determine the economic factors that steadily influenced reproductive trends in the Volga Federal District in 2000-2020, their regional differentiation. The hypothesis of the study: the dynamics of the birth rate is predetermined, among other things, by economic factors (of a general economic nature and economic activity of households). With a positive change in the economic well-being of the population and households, stable prerequisites are formed for the growth of the birth rate in the Volga Federal District.Methods: the correlation and regression analysis of the total fertility rate and economic predictors for 2000-2020 of the Volga Federal District regions was used. Econometric prerequisites for determining reproductive trends are formed based on changes in macro- and microeconomic indicators of the economic well-being of the region and individual households.Results: regional differences in the influence of economic factors on fertility are revealed: direct linear dependence on the volume of investments per capita and the level of employment; inverse dependence on the level of poverty and the share of household spending on food (except for the Republic of Bashkortostan). When assessing the inverse linear dependence on the indexation of prices for primary housing, the coefficient of determination is insufficient (except for the Udmurt Republic), as in the case of assessing the impact of the unemployment rate (the factor is insignificant for the Republic of Bashkortostan, Kirov Region, Perm Krai). The growth and decrease in monthly consumer spending lead to a decrease in the birth rate.Conclusions and Relevance: one-factor regression analysis showed that in the Volga Federal District, the formation of reproductive trends is negatively affected by an increase in the share of spending on essential goods. Multivariate regression analysis revealed a correlation of fertility rates with a steady increase in the level of employment. The presented approach can be used to describe the prerequisites for the formation of stable reproductive trends in other districts and regions of Russia for the implementation of preventive measures of the demographic policy of the state in order to maintain the stability and positive development of the demographic situation, prognostic estimates of trends of deviation from the positive trend
The sovereignty of the psychological space of adolescents and child-parent relations
В статье рассматриваются особенности формирования суверенности психологического пространства подростков, а также влияние детско-родительских отношений на данный процесс.The article examines the peculiarities of the formation of the sovereignty of the psychological space of adolescents, as well as the influence of child-parent relations on this process
Personality traits of teenagers, participating in youth non-governmental organisations
Based on diagnostic results, the article presents a comparative analysis of personality traits of seniour high school students, participating in youth nongovernmental organizations, and their peers, not participating in those. Obtained results are considered in the context of teenagers' self-actualization as part of of socially important activities.В статье представлен сравнительный анализ результатов диагностики личностных особенностей старшеклассников, участвующих в молодежных общественных объединениях, и их сверстников, не принимающих участия в них. Полученные результаты рассматриваются в контексте проблемы самореализации подростков в рамках социально значимой деятельности
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