Vibrational transfer functions for base excited systems

Computer program GD203 develops transfer functions to compute governing vibration environment for complex structures subjected to a base motion

Chaos properties and localization in Lorentz lattice gases

The thermodynamic formalism of Ruelle, Sinai, and Bowen, in which chaotic properties of dynamical systems are expressed in terms of a free energy-type function - called the topological pressure - is applied to a Lorentz Lattice Gas, as typical for diffusive systems with static disorder. In the limit of large system sizes, the mechanism and effects of localization on large clusters of scatterers in the calculation of the topological pressure are elucidated and supported by strong numerical evidence. Moreover it clarifies and illustrates a previous theoretical analysis [Appert et al. J. Stat. Phys. 87, chao-dyn/9607019] of this localization phenomenon.Comment: 32 pages, 19 Postscript figures, submitted to PR

A short note on the nested-sweep polarized traces method for the 2D Helmholtz equation

We present a variant of the solver in Zepeda-N\'u\~nez and Demanet (2014), for the 2D high-frequency Helmholtz equation in heterogeneous acoustic media. By changing the domain decomposition from a layered to a grid-like partition, this variant yields improved asymptotic online and offline runtimes and a lower memory footprint. The solver has online parallel complexity that scales \emph{sub linearly} as $\mathcal{O} \left( \frac{N}{P} \right)$, where $N$ is the number of volume unknowns, and $P$ is the number of processors, provided that $P = \mathcal{O}(N^{1/5})$. The variant in Zepeda-N\'u\~nez and Demanet (2014) only afforded $P = \mathcal{O}(N^{1/8})$. Algorithmic scalability is a prime requirement for wave simulation in regimes of interest for geophysical imaging.Comment: 5 pages, 5 figure

On detecting CP violation in a single neutrino oscillation channel at very long baselines

We propose a way of detecting CP violation in a single neutrino oscillation channel at very long baselines (on the order of several thousands of kilometers), given precise knowledge of the smallest mass-squared difference. It is shown that CP violation can be characterized by a shift in $L/E$ of the peak oscillation in the $\nu_e$--$\nu_\mu$ appearance channel, both in vacuum and in matter. In fact, matter effects enhance the shift at a fixed energy. We consider the case in which sub-GeV neutrinos are measured with varying baseline and also the case of a fixed baseline. For the varied baseline, accurate knowledge of the absolute neutrino flux would not be necessary; however, neutrinos must be distinguishable from antineutrinos. For the fixed baseline, it is shown that CP violation can be distinguished if the mixing angle $\theta_{13}$ were known.Comment: 8 pages, 9 figures; minor typos correcte

Randomly Driven Granular Fluids: collisional statistics and short scale structure

We present a molecular dynamics and kinetic theory study of granular material, modeled by inelastic hard disks, fluidized by a random driving force. The focus is on collisional averages and short distance correlations in the non-equilibrium steady state, in order to analyze in a quantitative manner the breakdown of molecular chaos, i.e. factorization of the two-particle distribution function, $f^{(2)}(x_1,x_2) \simeq \chi f^(1)(x_1) f^{(1)}(x_2)$ in a product of single particle ones, where $x_i = \{{\bf r}_i, {\bf v}_i \}$ with $i=1,2$ and $\chi$ represents the position correlation. We have found that molecular chaos is only violated in a small region of the two-particle phase space $\{x_1,x_2\}$, where there is a predominance of grazing collisions. The size of this singular region grows with increasing inelasticity. The existence of particle- and noise-induced recollisions magnifies the departure from mean field behavior. The implications of this breakdown in several physical quantities are explored.Comment: 28 pages, 16 figure

Binding-incompetent adenovirus facilitates molecular conjugate-mediated gene transfer by the receptor-mediated endocytosis pathway

Molecular conjugate vectors may be constructed that accomplish high efficiency gene transfer by the receptor-mediated endocytosis pathway. In order to mediate escape from lysosomal degradation, we have incorporated adenoviruses into the functional design of the conjugate. In doing so, however, we have introduced an additional ligand, which can bind to receptors on the cell surface, undermining the potential for cell specific targeting. To overcome this, we have treated the adenovirus with a monoclonal anti-fiber antibody, which renders the virus incapable of binding to its receptor. The result is a multi-functional molecular conjugate vector, which has preserved its binding specificity while at the same time being capable of preventing lysosomal degradation of endosome-internalized conjugate-DNA complexes. This finding indicates that adenoviral binding is not a prerequisite for adenoviral-mediated endosome disruption