EFFECTS OF FICUS THONNINGII EXTRACTS ON THE GASTROINTESTINAL TRACT AND CLINICAL BIOCHEMISTRY OF SUCKLING RATS

Ficus thonningii is commonly used in traditional medicine across the African continent. Using forty, 6-day old Sprague Dawley rats, we investigated the effects of crude Ficus thonningii extracts on growth, morphology and morphometry of the abdominal viscera, and clinical biochemistry of neonatal rats. The pups were orally gavaged once daily with either low (50 mg.kg-1 b.w), or high (500 mg.kg-1 b.w), doses of aqueous or methanolic F. thonningii leaf extracts while the control received distilled water. After 7, days of treatment, the pups were euthanased and gross morphometric measurements of the abdominal visceral organs were recorded. Samples of the liver, caecum and proximal small intestine were processed for histology. Plasma biochemical parameters were analysed colorimetrically. High methanolic doses of F. thonningii extracts exhibited trophic effects on the stomach while both aqueous and methanolic extracts had trophic effects on the ceacal mucosa of rats. No significant growth-promoting effects were observed in other visceral organs. Histological analysis revealed no mucosal damage or necrosis. Clinical biochemistry parameters were not abnormally altered. There was a significant decrease (

Hepatic capillariasis in a Cape ground squirrel (Xerus inaurus)

We report, for the first time, an incidental finding of Calodium hepaticum infestation in a sub-adult female Cape ground squirrel (Xerus inaurus). Post mortem examination of the squirrel revealed severe haemoperitoneum, splenomegaly and hepatomegaly with miliary white spots distributed diffusely throughout the hepatic parenchyma. Histologically the portal tracts in the liver showed granulomatous inflammation with fibrosis and numerous giant cells. Occasional adult worms were identified and there were multiple C. hepaticum eggs distributed diffusely throughout the portal tracts and the parenchyma. The spleen also contained C. hepaticum eggs. The genus Rattus is the primary host and reservoir of C. hepaticum, but C. hepaticum infections have been reported previously in other Sciuridae. Based on our findings, people should be cautious of the zoonotic potential of C. hepaticum, when they come into contact with the Cape ground squirrel

Applying psychological learning theory to helping students overcome learned difficulties in mathematics: An alternative approach to intervention

The appearance of systematic errors in computation suggests relatively unlinked computational knowledge to conceptual knowledge, and hence difficulties with forward learning of mathematics. The provision of programs of good teaching, where concrete materials are used to exemplify and thus legitimize algorithmic processes, frequently are not effective for use with upper primary students: systematic errors often resurface. A novel and quite alternate approach to intervention is the Old Way/New Way (O/N) strategy (Lyndon, 1989) based on psychological principles of memory, forgetting and interference. In this article, issues associated with intervention, systematic errors and upper primary students are addressed through a discussion of results of previous research into seventh graders' subtraction knowledge development by overcoming error patterns in subtraction computation. By comparing re-teaching strategies and O/N, it is proposed that both good teaching and effective intervention strategies should be integral to the craft of teaching, particularly in the middle school

Honey, a Gift from Nature to Health and Beauty: A Review

Benefits of honey are contributed by the composition of its elements such as glucose, fructose, glucose oxidase, vitamins and phenolic compounds. For health, honey can be used to treat wounds due to the antibacterial activity conferred by the hydrogen peroxide produced by glucose oxidase in honey. Anti-inflammatory, anti-oxidant, deodorizing and tissue regeneration activities in honey also help in the wound healing process. It can also be an alternative sweetener for diabetic patients to ensure compliance to a healthy diet. Moreover, honey exerts several effects such as lowering low density lipids and increasing high density lipids, thus reducing risk of atherosclerosis. In terms of beauty, honey can be used on skin and hair. It moisturizes skin through its natural humectant properties contributed by high contents of fructose and glucose. Honey treats acne on the skin due to its antibacterial activity, anti-inflammatory action and tissue repair. The hair can benefit from honey in such a way that the hair has abundance, and becomes easier to comb. However, there have not been as many studies regarding the use of honey in skin in comparison to its use for health. Therefore, future studies on honey could research its use, action and benefits in both cosmetics and dermatology

The effects of imidocarb dipropionate on gastric acid secretion in the anaesthetised adult female rat

(Zimbabwe Veterinary Journal, 2001, 32 (3&4): 57-63

Uterine torsion in a Sprague Dawley rat (Rattus norvegicus)

Uterine torsion is a twisting of the uterus or uterine horn perpendicular to its long axis.We report a case of uterine torsion in an adult breeding Sprague Dawley rat. The rat died a month after her last recorded delivery. Post mortem examination of the rat revealed 270° torsion of the right uterine horn. The uterus contained a single foetus. The liver was pale and enlarged. The rest of the viscera appeared normal. Histopathological examination showed acute hepatic necrosis and pulmonary congestion with mild lymphocytic infiltrates peribronchially. The acute hepatic necrosis may have been associated with septicaemia due to compromised blood vessels following the uterine torsion. The presence of a single foetus could have resulted in foeto-maternal disproportion with resultant uterine torsion. Torsion of the uterus can be accompanied by haemostatic and metabolic complications, which could have caused the death of the rat. Although uterine torsion is a rare condition in rats, it should be considered as a potential complication of gestation in animal breeding units

Anatomy of the hard palate and tongue of the indigenous Zimbabwean pig (Mukota)

(Zimbabwe Veterinary Journal, 1998, 29(3): 77-86