7 research outputs found

    Senior Recital: Andrew Ereddia, alto saxophone

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    This recital is presented in partial fulfillment of requirements for the degree Bachelor of Music in Performance. Mr. Ereddia studies saxophone with Sam Skelton.https://digitalcommons.kennesaw.edu/musicprograms/2077/thumbnail.jp

    Junior Recital: Andrew Ereddia, saxophone

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    This recital is presented in partial fulfillment of requirements for the degree Bachelor of Music in Performance. Mr. Ereddia studies saxophone with Sam Skelton.https://digitalcommons.kennesaw.edu/musicprograms/1918/thumbnail.jp

    Junior Recital: Simon Needle, jazz guitar

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    This recital is presented in partial fulfillment of requirements for the degree Bachelor of Music in Performance. Mr. Needle studies guitar with Trey Wright.https://digitalcommons.kennesaw.edu/musicprograms/2001/thumbnail.jp

    Junior Recital: Drew Lloyd, double bass

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    This recital is presented in partial fulfillment of requirements for the degree Bachelor of Music in Performance. Mr. Lloyd studies double bass with Marc Miller.https://digitalcommons.kennesaw.edu/musicprograms/1935/thumbnail.jp

    The C. elegans ephrin EFN-4 functions non-cell autonomously with heparan sulfate proteoglycans to promote axon outgrowth and branching

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    The Eph receptors and their cognate ephrin ligands play key roles in many aspects of nervous system development. These interactions typically occur within an individual tissue type, serving either to guide axons to their terminal targets or to define boundaries between the rhombomeres of the hindbrain. We have identified a novel role for the Caenorhabditis elegans ephrin EFN-4 in promoting primary neurite outgrowth in AIY interneurons and D-class motor neurons. Rescue experiments reveal that EFN-4 functions non-cell autonomously in the epidermis to promote primary neurite outgrowth. We also find that EFN-4 plays a role in promoting ectopic axon branching in a C. elegans model of X-linked Kallmann syndrome. In this context, EFN-4 functions non-cell autonomously in the body wall muscle, and in parallel with HS biosynthesis genes and HSPG core proteins, which function cell autonomously in the AIY neurons. This is the first report of an epidermal ephrin providing a developmental cue to the nervous system

    Junior Recital: Michael Opitz, saxophone

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    This recital is presented in partial fulfillment of requirements for the degree Bachelor of Music in Performance. Mr. Opitz studies saxophone with Sam Skelton.https://digitalcommons.kennesaw.edu/musicprograms/1043/thumbnail.jp

    The Caenorhabditis elegans Ephrin EFN-4 Functions Non-cell Autonomously with Heparan Sulfate Proteoglycans to Promote Axon Outgrowth and Branching

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    The Eph receptors and their cognate ephrin ligands play key roles in many aspects of nervous system development. These interactions typically occur within an individual tissue type, serving either to guide axons to their terminal targets or to define boundaries between the rhombomeres of the hindbrain. We have identified a novel role for theCaenorhabditis elegans ephrin EFN-4 in promoting primary neurite outgrowth in AIY interneurons and D-class motor neurons. Rescue experiments reveal that EFN-4 functions non-cell autonomously in the epidermis to promote primary neurite outgrowth. We also find that EFN-4 plays a role in promoting ectopic axon branching in a C. elegansmodel of X-linked Kallmann syndrome. In this context, EFN-4 functions non-cell autonomously in the body wall muscle, and in parallel with HS modification genes and HSPG core proteins. This is the first report of an epidermal ephrin providing a developmental cue to the nervous system
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