Türkiye’de Uygulanan Orta Vadeli Programın Ödemeler Dengesi Tahminleri Doğrultusunda Performansının Analizi

Many developed and developing countries, who want to fulfill their social responsibilities covering investment spending that requires long-term, are passed to the multi-year budgeting practices instead of the classic one-year budget execution. In this respect, Turkey has passed multi-year budgeting implementation in 2006. Multi-year budgeting method, which is called “Medium Term Expenditure System” in the World Bank studies, is being implemented in the framework of the Medium Term Programme (MTP) in Turkey. Macro economic objectives of MTP include the balance of payments targets as well as growth, employment, public finance and general level of prices. It is estimated in the three-year horizon about Exports, Imports, Trade Balance, Current Account Balance/GDP, and Foreign Trade Volume/GDP towards the balance of payments targets. In this study, the success performance in forecasting and targets of the MTP was analyzed according to the balance of payments targets. In this study, the following conclusion was reached: In Turkey, the level of achievement of the MTP’s estimates is behind a great deal of EU countries according to the size of the balance of payments

Türkiye’de Uygulanan Orta Vadeli Programın Ödemeler Dengesi Tahminleri Doğrultusunda Performansının Analizi

Many developed and developing countries, who want to fulfill their social responsibilities covering investment spending that requires long-term, are passed to the multi-year budgeting practices instead of the classic one-year budget execution. In this respect, Turkey has passed multi-year budgeting implementation in 2006. Multi-year budgeting method, which is called “Medium Term Expenditure System” in the World Bank studies, is being implemented in the framework of the Medium Term Programme (MTP) in Turkey. Macro economic objectives of MTP include the balance of payments targets as well as growth, employment, public finance and general level of prices. It is estimated in the three-year horizon about Exports, Imports, Trade Balance, Current Account Balance/GDP, and Foreign Trade Volume/GDP towards the balance of payments targets. In this study, the success performance in forecasting and targets of the MTP was analyzed according to the balance of payments targets. In this study, the following conclusion was reached: In Turkey, the level of achievement of the MTP’s estimates is behind a great deal of EU countries according to the size of the balance of payments

Evaluation of clinical follow-up of patients with A-V fistula

24.06.2019 tarihine kadar kullanımı yazar tarafından kısıtlanmıştırİstanbul Bilim Üniversitesi, Sağlık Bilimleri Enstitüsü, Organ Ve Doku Koordinatörlüğü Eğitim Yüksek Lisans ProgramıMateryal ve Yöntem: Araştırmanın örneklemi İstanbul Şişli FNH’de böbrek nakli öncesi diyalize girmek için A-V fistül açılan, nakil sonrası sonrası fistülleri çalışan hastalar oluşturmaktadır. Yürütülen çalışmaya22-65 yaş arası (ortalama=41,29±10,63 yıl) böbrek nakli yapılmış olan 100 kişi katılmıştır. Verilerin analizi için sosyal bilimlerde sıkça kullanılan SPSS.21 paket programı kullanılmıştır. Araştırmada yer alan sosyodemografik bilgiler için frekans ve betimleyici istatistik yöntemleri kullanılmıştır. Kategorik değişkenler içi farklılığı bulmak için ki-kare homojenlik ve kategorik değişkenler arası farklılığın tespiti için ki-kare bağımsızlık analizleri kullanılmıştır. Bulgular: Analizler sonucunda fistüllerin böbrek nakli sonrasında için yaşadıkları problemler arası farklılık görülmüştür. Kadın hastalar daha çok fistülün görüntüsünden rahatsız oldukları için kapatılmasını istemişlerdir. Fistül takılan hasta grubunda 22-40 yaş arası ve düşük eğitim seviyesi için günlük aktiviteleri daha çok etkilediği görülmüştür. Nakil sonrası fistülünün kapatılmasını en çok isteyen hastalar 22-40 yaş arası hastalar ve fistülü sol kolunda bulunan hastalardır. Fistülü sol kolunda bulunan bireylerin daha çok kalp problemi yaşadıkları görülmüştür. BUN ve KREATİN değerlerinin fistülün kapatılmasını isteme veya istememe durumunda istatistiksel fark bulunmamıştır. Sonuç: Elde edilen bulgular %95 güven aralığında ve p=0,05 anlamlılık düzeyinde incelenmiştir.Material and Method: The sampling of the study consists of the patients, on whom A-V fistula was opened before kidney transplantation and continue working in the postoperative period in Istanbul Şişli FNH. Total 100 patients (of which 71 patients (72,4%) are married, 27 single (27,6%) and 2 patients whose marital status are not known) and who had received kidney transplant, participated in the study. The participants vary between age of 22-65. The SPSS.21 package program is used for the data analysis. The frequency and definitive statistics methods were used for the socio-demographic data study. The Chi-Square Homogeneity Analysis is used to determine the differences in intra-categorical variables; and the Chi-Square Independence Analysis for the differences between the categorical variables. Findings: Patients were analyzed according to the problems their experiencing according to the problems about the fistulas opened in the patients. Since the female patients pay attention to their appearance, they would like to have it removed. It is observed that the lower the age and education, the fistula influence becomes greater. It was also observed that the individuals with fistula on their left arms have more cardiac problems as well as hypertension and tachycardia. No statistically significant difference is seen for the fistula removal based on the BUN and CREATINE values. The patients prefer to have fistulas were on their left arms. Results: The findings were examined with 95% confidence interval and at p=0,05 significance level

Evaluation of clinical follow-up of patients with arteriovenous fistula

İstanbul Bilim Üniversitesi, Tıp Fakültesi.Amaç: Hastaların çalışan arteriyovenöz fistül (AVF)’lerini böbrek nakli sonrası kapattırma veya kapattırmama istekleri, kararlarının nedenlerinin belirlenmesi, bu kararlarının diğer parametreler ile ilişkileri araştırıldı. Hastalar ve yöntemler: Araştırmanın örneklemini Ocak 2009 - Aralık 2015 tarihleri arasında İstanbul Şişli FNH’de böbrek nakli öncesi diyalize girmek için AVF açılan, nakil sonrası fistülleri çalışan 100 hasta (60 erkek, 40 kadın; ort. yaş 41.3±10.6 yıl; dağılım 22-65 yıl) oluşturdu. Hastaların sosyodemografik ve fistüle bağlı özellikleri, 25 maddelik Veri Toplama Formu ile sorgulandı.Objectives: This study aims to investigate the demands of the patients whether to close down or not to close down the working arteriovenous fistulas (AVF) subsequent to kidney transplantation, determining the reasons for decision, and relationships of these decision with other parameters. Patients and methods: The sampling of the study consists of 100 patients (60 males, 40 females; mean age 41.3±10.6 years; range 22 to 65 years), on whom AVF was opened before kidney transplantation and continued to work in the postoperative period in Istanbul Şişli FNH between January 2009 - December 2015. Sociodemographic and fistula-related characteristics of the patients were questioned using a 25-item Data Collection Form

The Relationship Between Serum Endocan Level and Aortic Elastic Properties in Patients With Newly Diagnosed Essential Hypertension.

Endothelial dysfunction plays role in the generation of both essential hypertension (EH) and aortic stiffness. We evaluated the relationship between serum endocan level and aortic elastic properties (AEPs) assessed with the aortic strain, aortic distensibility, and aortic stiffness index by echocardiography. Newly diagnosed EH patients (n = 67) and controls (n = 70) were included in the study. The EH group was subdivided into stage 1 and 2 EH groups. A higher endocan level was found in the EH group, compared to the controls (34.2 ± 13.0 vs 24.1 ± 7.3 ng/mL, respectively, P < .001). All the AEP parameters were worse in the EH group, compared to the controls. Further, endocan levels correlated with aortic distensibility (r = -0.305, P < .001) and aortic strain (r = -0.181, P = .038), but not with aortic stiffness index (r = 0.162, P = .064) in the whole study population. Aortic elastic properties deteriorate and serum endocan level increases in patients with EH. Moreover, serum endocan level shows a correlation with deteriorated AEPs, and hence may a surrogate marker of escalating aortic stiffness in patients with newly diagnosed EH

Evaluation of The Nutrition and Food Safety Knowledge and Behaviour of The Young

Bu çalışma Gazi Üniversitesi'nin farklı fakültelerinde okuyan öğrencilerin beslenme ile gıda güvenliği bilgisi, alışkanlıkları öz yeterlilik ve fiziksel aktivite durumlarını değerlendirmek amacıyla yapılmıştır. Çalışmaya Gazi üniversitesinin sağlık bilimleri (n=140), sosyal bilimler (n=46) ve fen bilimlerinde (n=64) öğrenim gören 68'i erkek, 182'si kız toplam 250 öğrenci dahil edilmiştir. Öğrencilere Turconi ve arkadaşlarının (2003) geliştirdiği toplam 9 bölüm ve 84 sorudan oluşan bir ölçek uygulanmıştır. Veriler SPSS 22.0 programıyla değerlendirilmiştir. Araştırmaya katılan öğrencilerin yaş ortalaması 19.74±1.84 yıldır. Şişmanlığın belirlenmesinde kullanılan beden kütle indeksi (BKİ) değerinin ortalaması erkeklerde ve kızlarda sırasıyla 22.55±2.75 ve 21.25±2.99 kg/m2 'dır. Sağlık bilimlerinde okuyan öğrencilerin beslenme alışkanlığı (BA), sağlıklı/sağlıksız beslenme alışkanlıkları ve besinler (SSBAB), beslenme bilgisi (BB) ve gıda güvenliği bilgisi (GGB) puanları fen ve sosyal bilimlerde okuyan öğrencilerden anlamlı derecede yüksektir. Bütün alt gruplar cinsiyete göre değerlendirildiğinde kız öğrencilerin puanlarının erkeklerden yüksek olduğu ve bu farkın öz yeterlilik haricinde diğer bütün alt gruplarda anlamlı olduğu tespit edilmiştir (p<0.05). Sadece erkeklerin fiziksel aktivite puanları kızlara göre daha yüksektir (p<0.05). Öğrencilerin BKI değerleri artıkça gıda güvenliği bilgisi (GGB) ve sağlıklı/sağlıksız beslenme alışkanlıkları bilgisi (SSBAB) puanlarının düştüğü saptanmıştır (p<0.05). Araştırmada sağlık bilimlerinde okuyan öğrencilerin beslenme bilgi ve alışkanlıklarının diğer bilimlerde okuyan öğrencilerden daha iyi olduğu sonucuna ulaşılmıştırThis study was conducted in order to evaluate the nutrition knowledge, attitude and behaviour states of students studying in different departments of Gazi University. 250 students (68 male and 182 female) were included to this study who were studying in health sciences (n=140), social sciences (n=46) and physical sciences (n=64). Developed by Turconi et al. (2003), a scale of 9 sections and 84 questions was applied to the students. Data were evaluated through SPSS 22.0 program. The average age of all students was19.74&plusmn;1.84 years. The averages of the body mass index (BMI) that is used in defining being overweight were 22.55&plusmn;2.75 and 21.25&plusmn;2.99 kg/m 2 in the males and females respectively than females. Food habits (FH), healthy / unhealthy diet habits and foods (HUDF), nutrition knowledge (NK) and food safety knowledge (FSK) scores of students studying in health science were significantly higher than the students studying in science and social sciences. When all subgroups were evaluated according to sex, it was found that the scores of female students were higher than males and this difference was significant in all other subgroups except for self - efficacy (SE) (p&lt;0.05). Only physical activity scores of males were higher than females (p &lt;0.05). It was observed that among students, those with higher BMI have lower food safety knowledge (FSK) and healthy/unhealthy diet habits knowledge (HUDF) scores (p&lt;0.05) than the others. In the study, it was concluded that the nutrition knowledge and habits of students studying in the health science were better than the students studying in other fields

PROPSEA, safety evaluation of palbociclib and ribociclib in older patients with breast cancer: A prospective real-world TOG study

Introduction: In this study, the toxicities and management of palbociclib and ribociclib in older patients (≥65 years) with metastatic breast cancer patients were investigated. Materials and Methods: Among older patients receiving palbociclib and ribociclib, Geriatric 8 (G8) and Groningen Frailty Index were used to evaluate frailty status. Dose modifications, drug withdrawal and other serious adverse events (SAEs) were recorded and analyzed according to baseline patient characteristics. Results: A total of 160 patients from 28 centers in Turkey were included (palbociclib = 76, ribociclib = 84). Forty-three patients were ≥ 75 years of age. The most common cause of first dose modification was neutropenia for both drugs (97% palbociclib, 69% ribociclib). Liver function tests elevation (10%) and renal function impairment (6%) were also causes for ribociclib dose modification. Drug withdrawal rate was 3.9% for palbociclib and 6% for ribociclib. SAEs were seen in 11.8% of those taking palbociclib and 15.5% of those on riboclib. An ECOG performance status of ≥2 and being older than 75 years were associated with dose reductions. Severe neutropenia was more common in patients with non-bone-only metastatic disease, those receiving treatment third-line therapy or higher, coexistance of non-neutropenic hematological side effects (for ribociclib). Neutropenia was less common among patients with obesity. Discussion: Our results show that it can be reasonable to start palbociclib and ribociclib at reduced dose in patients aged ≥75 years and/or with an ECOG performance status ≥2

A multicentre prospective analysis of the incidence of pemphigoid diseases in Turkey

Background The differentiation between the pemphigoid diseases is essential for treatment and prognosis. In Turkey, data on the incidence of these diseases are insufficient. Our aim in this study is to determine the incidence, demographics and clinical characteristics associated with diseases of the pemphigoid group. Methods We prospectively analysed 295 patients with pemphigoid who visited dermatology clinics of tertiary referral hospitals in 12 different regions of Turkey within a year. The diagnosis was based on clinical, histopathological, direct immunofluorescence (DIF) and serological (multivariant enzyme-linked immunosorbent assay [ELISA], indirect immunofluorescence and mosaic-based BIOCHIP) examinations. Clinical and demographic findings, aetiological factors and concomitant diseases observed in the patients were recorded. Results A total of 295 (female/male ratio: 1.7/1) patients with pemphigoid were diagnosed in 1-year period. The overall incidence rate of pemphigoid diseases was found to be 3.55 cases per million-years. The ratio of pemphigoid group diseases to pemphigus group diseases was 1.6. The most common pemphigoid type was bullous pemphigoid (BP, 93.2%). The others were epidermolysis bullosa acquisita (3.1%), pemphigoid gestationis (2.4%), linear IgA disease (1%) and mucous membrane pemphigoid (0.3%). The most common (26.8%) possible trigger of the bullous pemphigoid was gliptin derivative drugs. The most common concomitant diseases with pemphigoid were cardiovascular (27.8%) and neurological diseases (23.7%). Conclusions This study showed that the increased frequency of bullous pemphigoid reversed the pemphigoid/pemphigus ratio in Turkey. Further studies are warranted regarding the reasons for this increase

Major and minor salivary gland cancers: A multicenter retrospective study

Background: Most of the studies on salivary gland cancers are limited for various reasons such as being single-center, small number of patients, including only major or minor SGCs, or only including epidemiological data. Methods: A total of 37 medical oncology clinics from different regions of Turkey participated in this retrospective-multicenter study. The analyzed data included clinical and demographical features, primary treatment, metastasis localizations, and treatments and includes certain pathologic features. Results: The study included data from a total of 443 SGCs. 56.7% was in major salivary glands and 43.3% was in minor salivary glands. Distant metastasis in the major SGCs was statistically significantly more common than in the minor SGCs, locoregional recurrence was statistically significantly more common in the minor SGCs than in the major SGCs (p = 0.003). Conclusions: Epidemiological information, metastasis and recurrence patterns, treatment modalities, and survival analysis of the patients over 20 years of follow-up are presented