359 research outputs found
Noise thermometry applied to thermoelectric measurements in InAs nanowires
We apply noise thermometry to characterize charge and thermoelectric
transport in single InAs nanowires (NWs) at a bath temperature of 4.2 K. Shot
noise measurements identify elastic diffusive transport in our NWs with
negligible electron-phonon interaction. This enables us to set up a measurement
of the diffusion thermopower. Unlike in previous approaches, we make use of a
primary electronic noise thermometry to calibrate a thermal bias across the NW.
In particular, this enables us to apply a contact heating scheme, which is much
more efficient in creating the thermal bias as compared to conventional
substrate heating. The measured thermoelectric Seebeck coefficient exhibits
strong mesoscopic fluctuations in dependence on the back-gate voltage that is
used to tune the NW carrier density. We analyze the transport and
thermoelectric data in terms of approximate Mott's thermopower relation and to
evaluate a gate-voltage to Fermi energy conversion factor
Local noise in a diffusive conductor
The control and measurement of local non-equilibrium configurations is of
utmost importance in applications on energy harvesting, thermoelectrics and
heat management in nano-electronics. This challenging task can be achieved with
the help of various local probes, prominent examples including superconducting
or quantum dot based tunnel junctions, classical and quantum resistors, and
Raman thermography. Beyond time-averaged properties, valuable information can
also be gained from spontaneous fluctuations of current (noise). From these
perspective, however, a fundamental constraint is set by current conservation,
which makes noise a characteristic of the whole conductor, rather than some
part of it. Here we demonstrate how to remove this obstacle and pick up a local
noise temperature of a current biased diffusive conductor with the help of a
miniature noise probe. This approach is virtually noninvasive and extends
primary local measurements towards strongly non-equilibrium regimes.Comment: minor revision, accepted in Scientific Report
Topological Phenomena in the Real Periodic Sine-Gordon Theory
The set of real finite-gap Sine-Gordon solutions corresponding to a fixed
spectral curve consists of several connected components. A simple explicit
description of these components obtained by the authors recently is used to
study the consequences of this property. In particular this description allows
to calculate the topological charge of solutions (the averaging of the
-derivative of the potential) and to show that the averaging of other
standard conservation laws is the same for all components.Comment: LaTeX, 18 pages, 3 figure
Isoperiodic deformations of the acoustic operator and periodic solutions of the Harry Dym equation
We consider the problem of describing the possible spectra of an acoustic
operator with a periodic finite-gap density. We construct flows on the moduli
space of algebraic Riemann surfaces that preserve the periods of the
corresponding operator. By a suitable extension of the phase space, these
equations can be written with quadratic irrationalities.Comment: 15 page
Wannier functions for quasi-periodic finite-gap potentials
In this paper we consider Wannier functions of quasi-periodic g-gap () potentials and investigate their main properties. In particular, we discuss
the problem of averaging underlying the definition of Wannier functions for
both periodic and quasi-periodic potentials and express Bloch functions and
quasi-momenta in terms of hyperelliptic functions. Using this approach
we derive a power series expansion of the Wannier function for quasi-periodic
potentials valid at and an asymptotic expansion valid at large
distance. These functions are important for a number of applied problems
Spectra of random Hermitian matrices with a small-rank external source: supercritical and subcritical regimes
Random Hermitian matrices with a source term arise, for instance, in the
study of non-intersecting Brownian walkers \cite{Adler:2009a, Daems:2007} and
sample covariance matrices \cite{Baik:2005}.
We consider the case when the external source matrix has two
distinct real eigenvalues: with multiplicity and zero with multiplicity
. The source is small in the sense that is finite or , for . For a Gaussian potential, P\'ech\'e
\cite{Peche:2006} showed that for sufficiently small (the subcritical
regime) the external source has no leading-order effect on the eigenvalues,
while for sufficiently large (the supercritical regime) eigenvalues
exit the bulk of the spectrum and behave as the eigenvalues of
Gaussian unitary ensemble (GUE). We establish the universality of these results
for a general class of analytic potentials in the supercritical and subcritical
regimes.Comment: 41 pages, 4 figure
Analysis of the ATR-Chk1 and ATM-Chk2 pathways in male breast cancer revealed the prognostic significance of ATR expression
The ATR-Chk1 and ATM-Chk2 pathways are central in DNA damage repair (DDR) and their over-activation may confer aggressive molecular features, being an adaptive response to endogenous DNA damage and oncogene-induced replication stress. Herein we investigated the ATR-Chk1 and ATM-Chk2 signalings in male breast cancer (MBC). The expression of DDR kinases (pATR, pATM, pChk1, pChk2, and pWee1) and DNA damage markers (pRPA32 and γ-H2AX) was evaluated by immunohistochemistry in 289 MBC samples to assess their association. Survival analyses were carried out in 112 patients. Survival curves were estimated with the Kaplan-Meier method and compared by log-rank test. Cox proportional regression models were generated to identify variables impacting survival outcomes. The expression of pATR conferred poorer survival outcomes (log rank p = 0.013, p = 0.007 and p = 0.010 for overall, 15- and 10-year survival, respectively). Multivariate Cox models of 10-year survival and overall indicated that pATR expression, alone or combined with pChk2, was an independent predictor of adverse outcomes (10-year survival: pATR: HR 2.74, 95% CI: 1.23–6.10; pATR/pChk2: HR 2.92, 95% CI: 1.35–6.33; overall survival: pATR: HR 2.58, 95% CI: 1.20–5.53; pATR/pChk2: HR 2.89, 95% CI: 1.37–6.12). Overall, the ATR/ATM-initiated molecular cascade seems to be active in a fraction of MBC patients and may represent a negative prognostic factor
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