4 research outputs found

    Propuesta de intervención en la salud pública en el departamento de Arauca

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    Mediante el ASIS (Análisis de Situación de Salud) del departamento de Arauca se evidencia claramente un estudio de la población en cuanto a la salud pública, es por ello que se busca mediante este trabajo investigativo identificar problemas de interés de salud pública en el departamento y estructurar propuestas de intervención con el fin de mejorar tanto la calidad de vida de las personas como también el garantizar mediante los promotores de salud el derecho a la vida y a un buen goce de salud. La propuesta se centra y se evidencia con cifras y datos sobre las enfermedades transmisibles (Infecciones respiratorias agudas, tuberculosis, VIH – SIDA) que presenta la comunidad del departamento de Arauca y a su vez se plantean las actividades, metodologías, actores involucrados y resultados esperados para disminuir la tasa de mortalidad por dichas enfermedades. Dichas enfermedades se engloban en la agrupación de mortalidad especifica por subgrupo y son una problemática de salud pública que se ha incrementado en los últimos años en Arauca.Through the ASIS (Health Situation Analysis) of the department of Arauca, a study of the population in terms of public health is clearly evidenced, which is why this research work seeks to identify problems of public health interest in the department and structure intervention proposals in order to improve both the quality of life of people as well as guarantee the right to life and good health through health promoters. The proposal focuses and is evidenced with figures and data on communicable diseases (acute respiratory infections, tuberculosis, HIV - AIDS) presented by the community of the department of Arauca and at the same time the activities, methodologies, actors involved and expected results for reduce the mortality rate from these diseases. These diseases are included in the grouping of specific mortality by subgroup and are a public health problem that has increased in recent years in Arauca

    American College of Rheumatology Provisional Criteria for Clinically Relevant Improvement in Children and Adolescents With Childhood-Onset Systemic Lupus Erythematosus

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    10.1002/acr.23834ARTHRITIS CARE & RESEARCH715579-59

    Biodiversidad para el desarrollo. El manejo sostenible de ecosistemas como aporte al bienestar humano

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    El Instituto Humboldt, en su plan estratégico 2005 -2010 «Biodiversidad para el desarrollo: el manejo sostenible de ecosistemas como aporte al bienestar humano», le apuesta al manejo sostenible de ecosistemas desde una visión integral de los mismos, donde se busca el balance entre conservación, uso sostenible y distribución justa y equitativa de los beneficios derivados de los recursos de la biodiversidad. Este enfoque reconoce a los seres humanos como parte integral de los ecosistemas y por tanto, tiene en cuenta las relaciones y vínculos entre el bienestar humano y su potencial para contribuir a la disminución de la pobreza.BOGOTA D.C

    American college of rheumatology provisional criteria for clinically relevant improvement in children and adolescents with childhood-onset systemic Lupus erythematosus

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    To develop a Childhood Lupus Improvement Index (CHILI) as a tool to measure response to therapy in childhood-onset systemic lupus erythematosus (cSLE), with a focus on clinically relevant improvement (CRIcSLE). Methods Pediatric nephrology and rheumatology subspecialists (n = 213) experienced in cSLE management were invited to define CRIcSLE and rate a total of 433 unique patient profiles for the presence/absence of CRIcSLE. Patient profiles included the following cSLE core response variables (CRVs): global assessment of patient well-being (patient-global), physician assessment of cSLE activity (MD-global), disease activity index score (here, we used the Systemic Lupus Erythematosus Disease Activity Index), urine protein-to-creatinine ratio, and Child Health Questionnaire physical summary score. Percentage and absolute changes in these cSLE-CRVs (baseline versus follow-up) were considered in order to develop candidate algorithms and validate their performance (sensitivity, specificity, area under the receiver operating characteristic curve [AUC]; range 0-1). Results During an international consensus conference, unanimous agreement on a definition of CRIcSLE was achieved; cSLE experts (n = 13) concurred (100%) that the preferred CHILI algorithm considers absolute changes in the cSLE-CRVs. After transformation to a range of 0-100, a CHILI score of >= 54 had outstanding accuracy for identifying CRIcSLE (AUC 0.93, sensitivity 81.1%, and specificity 84.2%). CHILI scores also reflect minor, moderate, and major improvement for values exceeding 15, 68, and 92, respectively (all AUC >= 0.92, sensitivity >= 93.1%, and specificity >= 73.4%). Conclusion The CHILI is a new, seemingly highly accurate index for measuring CRI in cSLE over time. This index is useful to categorize the degree of response to therapy in children and adolescents with cSLE.715579590CNPQ - Conselho Nacional de Desenvolvimento Científico e TecnológicoFAPESP – Fundação de Amparo à Pesquisa Do Estado De São Paulo303422/2015-7; 7/2016-9; 304255/2015-7215/03756-
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