66 research outputs found
Respiratory muscle training in patients recovering recent open cardio-thoracic surgery: a randomized-controlled trial.
Objectives- To evaluate the clinical efficacy and feasibility of an expiratory muscle training (EMT) device (Respiliftâ„¢) applied to patients recovering from recent open cardio-thoracic surgery (CTS).
Design- Prospective, double-blind, 14-day randomised-controlled trial.
Participants and setting- 60 inpatients recovering from recent CTS and early admitted to a pulmonary rehabilitation program.
Interventions- Chest physiotherapy plus EMT with a resistive load of 30 cm H2O for active group and chest physiotherapy plus EMT with a sham load for control group.
Measures- Changes in maximal expiratory pressure (MEP) was considered as primary outcome, while maximal inspiratory pressures (MIP), dynamic and static lung volumes, oxygenation, perceived symptoms of dyspnoea, thoracic pain and well being (evaluated by visual analogic scale-VAS) and general health status were considered secondary outcomes.
Results- All outcomes recorded showed significant improvements in both groups; however, the change of MEP (+34.2 mmHg, p<0.001 and +26.1%, p<0.001 for absolute and % of predicted, respectively) was significantly higher in Active group. Also VAS-dyspnoea improved faster and more significantly (p<0.05) at day 12 and 14 in Active group when compared with Control. The drop out rate was 6%, without differences between groups.
Conclusions- In patients recovering from recent CTS specific EMT by Respiliftâ„¢ is feasible and effective
Clinical Study Respiratory Muscle Training in Patients Recovering Recent Open Cardiothoracic Surgery: A Randomized-Controlled Trial
Objectives. To evaluate the clinical efficacy and feasibility of an expiratory muscle training (EMT) device (Respilift) applied to patients recovering from recent open cardiothoracic surgery (CTS). Design. Prospective, double-blind, 14-day randomisedcontrolled trial. Participants and Setting. A total of 60 inpatients recovering from recent CTS and early admitted to a pulmonary rehabilitation program. Interventions. Chest physiotherapy plus EMT with a resistive load of 30 cm H 2 O for active group and chest physiotherapy plus EMT with a sham load for control group. Measures. Changes in maximal expiratory pressure (MEP) were considered as primary outcome, while maximal inspiratory pressures (MIP), dynamic and static lung volumes, oxygenation, perceived symptoms of dyspnoea, thoracic pain, and well being (evaluated by visual analogic scale-VAS) and general health status were considered secondary outcomes. Results. All outcomes recorded showed significant improvements in both groups; however, the change of MEP (+34.2 mmHg, < 0.001 and +26.1%, < 0.001 for absolute and % of predicted, resp.) was significantly higher in active group. Also VAS dyspnoea improved faster and more significantly ( < 0.05) at day 12, and 14 in active group when compared with control. The drop-out rate was 6%, without differences between groups. Conclusions. In patients recovering from recent CTS, specific EMT by Respilift is feasible and effective. This trial is registered with ClinicalTrials.gov NCT01510275
Kyphoplasty vs conservative treatment: a case-control study in 110 post-menopausal women population. Is kyphoplasty better than conservative treatment?
Abstract. – OBJECTIVE: Osteoporosis is a
highly prevalent disease worldwide. Consequences
of vertebral osteoporotic fractures include
pain and progressive vertebral collapse
resulting in spinal kyphosis, decreased quality
of life, disability and mortality. Minimally invasive
procedures represent an advance to the treatment
of osteoporotic VCFs. Despite encouraging
results reported by many authors, surgical intervention
in an osteoporotic spine is fraught with
difficulties. Advanced patients age and comorbidities
are of great concern.
PATIENTS AND METHODS: We designed a
retrospective case-control study on 110 postmenopausal
women consecutively visited at our
institution. Study population was split in a surgical
and a conservative cohort, according to the
provided treatment.
RESULTS: Kyphoplasty treated patients had
lower back pain VAS scores at 1 month as compared
with conservatively treated patients (p <
0.05). EQ5D validated questionnaire also showed
a better quality of life at 1 month for surgically
treated patients (p < 0.05). SF-12 scores showed
greater improvements at 1 month and 3 months
with statistically significant difference between
the two groups just at 3 months (p < 0.05). At 12
months, scores from all scales were not statistically
different between the two cohorts, although
surgically treated patients showed better trends
than conservatively treated patients in pain and
quality of life. Kyphoplasty was able to restore
more than 54.55% of the original segmental
kyphosis, whereas patients in conservative cohort
lost 6.67% of the original segmental kyphosis
on average.
CONCLUSIONS: Kyphoplasty is a modern
minimal invasive surgery, allowing faster recovery
than bracing treatment. It can avoid the deformity
in kyphosis due to VCF. In fact, the risk
to develop a new vertebral fracture after the first
one is very high
Sex-based electroclinical differences and prognostic factors in epilepsy with eyelid myoclonia
Although a striking female preponderance has been consistently reported in epilepsy with eyelid myoclonia (EEM), no study has specifically explored the variability of clinical presentation according to sex in this syndrome. Here, we aimed to investigate sex-specific electroclinical differences and prognostic determinants in EEM. Data from 267 EEM patients were retrospectively analyzed by the EEM Study Group, and a dedicated multivariable logistic regression analysis was developed separately for each sex. We found that females with EEM showed a significantly higher rate of persistence of photosensitivity and eye closure sensitivity at the last visit, along with a higher prevalence of migraine with/without aura, whereas males with EEM presented a higher rate of borderline intellectual functioning/intellectual disability. In female patients, multivariable logistic regression analysis revealed age at epilepsy onset, eyelid myoclonia status epilepticus, psychiatric comorbidities, and catamenial seizures as significant predictors of drug resistance. In male patients, a history of febrile seizures was the only predictor of drug resistance. Hence, our study reveals sex-specific differences in terms of both electroclinical features and prognostic factors. Our findings support the importance of a sex-based personalized approach in epilepsy care and research, especially in genetic generalized epilepsies
The spectrum of epilepsy with eyelid myoclonia: delineation of disease subtypes from a large multicenter study
Objective Epilepsy with eyelid myoclonia (EEM) has been associated with marked clinical heterogeneity. Early epilepsy onset has been recently linked to lower chances of achieving sustained remission and to a less favorable neuropsychiatric outcome. However, much work is still needed to better delineate this epilepsy syndrome. Methods In this multicenter retrospective cohort study, we included 267 EEM patients from nine countries. Data on electroclinical and demographic features, intellectual functioning, migraine with or without aura, family history of epilepsy, and epilepsy syndromes in relatives were collected in each patient. The impact of age at epilepsy onset (AEO) on EEM clinical features was investigated, along with the distinctive clinical characteristics of patients showing sporadic myoclonia involving body regions other than eyelids (body-MYO). Results Kernel density estimation revealed a trimodal distribution of AEO, and Fisher-Jenks optimization disclosed three EEM subgroups: early onset (EO-EEM), intermediate onset (IO-EEM), and late onset (LO-EEM). EO-EEM was associated with the highest rate of intellectual disability, antiseizure medication refractoriness, and psychiatric comorbidities and with the lowest rate of family history of epilepsy. LO-EEM was associated with the highest proportion of body-MYO and generalized tonic-clonic seizures (GTCS), whereas IO-EEM had the lowest observed rate of additional findings. A family history of EEM was significantly more frequent in IO-EEM and LO-EEM compared with EO-EEM. In the subset of patients with body-MYO (58/267), we observed a significantly higher rate of migraine and GTCS but no relevant differences in other electroclinical features and seizure outcome. Significance Based on AEO, we identified consistent EEM subtypes characterized by distinct electroclinical and familial features. Our observations shed new light on the spectrum of clinical features of this generalized epilepsy syndrome and may help clinicians toward a more accurate classification and prognostic profiling of EEM patients
Maria Nallino (1908-1974) and the Birth of Arabic and Islamic studies at Ca’ Foscari
This essay, based on bibliographic and archival material, focuses on the academic figure Maria Nallino, a scholar whose voluminous body of work ranges from classicism to modernity with equal fluency and expertise. Daughter of the famous Orientalist Carlo Alfonso Nallino (1872-1938), whose work she gathered and actively promoted, her arrival at Ca’ Foscari (1962) inaugurated Arabic and Islamic studies in Venice
Les noms personnels en somali
Cerulli Enrico. Les noms personnels en somali. In: Onomastica. Revue Internationale de Toponymie et d'Anthroponymie, 2e année N°2, juin 1948. Deuxième congrès international de toponymie et d'anthroponymie (3e et dernière série) pp. 139-142
I manoscritti etiopici della Chester Beatty Library in Dublino.
Reprinted from Classe di scienze morali, storiche e filologiche VolXI (1965)Reprinted from : Classe di scienze morali, storiche e filologiche. Vol.XI (1965
Documenti arabi per la storia dell'Etiopia.
Reprinted from Memorie della R Accademia nazionale del Lincei Classe di scienze morali, storiche e filologiche, ser 6, v 4, fasc
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