Isolasi Dan Karakterisasi Bakteri Endofit Penghasil Inhibitor α-Glukosidase Dari Tanaman Pare (Momordica Charantia L)

Diabetes merupakan penyakit metabolik yang serius di Indonesia. Jumlah penderita diabetes mengalami peningkatan setiap tahunnya. Inhibitor α-glukosidase merupakan senyawa yang dapat menghambat enzim α-glukosidase sehingga bermanfaat sebagai obat antidiabetes. Tanaman Pare (Momordica charantia) diketahui memiliki kasiat sebagai anti diabetes. Senyawa aktif yang dihasilkan tanaman tersebut dapat berasal dari endofit yang hidup di dalam jaringan tanaman. Eksplorasi bakteri endofit dari tanaman pare merupakan salah satu cara untuk mendapatkan isolat bakteri penghasil inhibitor enzim α-glukosidase. Isolasi bakteri dilakukan dengan menginokulasikan sampel tanaman yang telah disterilisasi permukaan pada media agar. Isolat bakteri yang didapat selanjutnya dimurnikan dan di karakterisasi lebih lanjut baik morfologi maupun aktivitas inhibitor α-glukosidasenya. Pengujian aktivitas inhibitor α-glukosidase menggunakan metode spektrofotometer dengan nitrofenil-α-D-glukopiranosida sebagai substrat. Hasil penelitian diperoleh 5 isolat bakteri endofit penghasil inhibior α-glukosidase. Penghambatan terbesar ditunjukkan oleh isolat bakteri Ad 1 yaitu sebesar 27,4%

Operation der Rektozele die gynäkologische Perspektive

Eine Rektozele ist nicht selten Langzeitfolge perinealer Geburtsverletzungen. Sie geht mit Senkungsbeschwerden und oft einer Enddarmobstipation einher. Die primäre Therapie ist stets konservativ (Beckenbodentraining, Pessare). Gynäkologische Operationen der Wahl sind hintere Kolporrhaphie und Sakrokolpopexie mit anatomischen Erfolgsraten bis 80%.Rectocele is frequently a consequence of a perineal trauma during childbirth. It is associated with symptoms of perineal descent and often with obstructed defecation. The primary therapy is always conservative (pelvic floor training, pessary). Gynecological procedures of choice are posterior colporrhaphy and sacrocolpopexy with anatomical success rates of up to 80%.(VLID)359545

Palpation für das Beckenbodentraining

This book provides information about this rather uncommon technique and lists the indications, applications and advantages of vaginal palpation

International Urogynecology Journal / Anterior colporrhaphy : a standard operation? Systematic review of the technical aspects of a common procedure in randomized controlled trials

Introduction Anterior colporrhaphy (AC) is considered a standard procedure and is performed all over the world. However, not a single step of the procedure has ever been truly standardized and the rates of failure show a wide range in the literature from 0% up to 92%. The aim of this systematic review was to evaluate the differences in technique and procedure worldwide. Methods We performed a systematic literature search up to March 2016 using the MeSH terms “(anterior AND (colporrhaph* or colporhaph* or repair* or cystocel*)” using Preferred Reporting Items for Sytematic Reviews and Meta-Analyses (PRISMA). Only randomized controlled trials (RCT) were included in the systematic review. A 14-point checklist was used to assess the quality of surgery undertaken in each RCT. Results Forty RCTs from all over the world were included in the review. The indication for AC was urinary incontinence and/or pelvic organ prolapse. A detailed description of colporrhaphy was not provided even in the well-conducted RCTs. The review showed differences in each step of the procedure, in perioperative care, in anesthesia and in surgeon experience. Conclusion Our results highlight the problems concerning AC with the great range in postoperative outcomes. There is diversity in the anatomical structures used in the repair, in perioperative care and in the procedure itself.(VLID)358041

Surgcial approaches.

<p>Surgcial approaches.</p