Changes in three-dimensional and thermal measures during rheumatoid arthritis flare

A 45-year-old Caucasian female with well-controlled rheumatoid arthritis was imaged. Nine days later, she developed an acute flare of her symptoms and was re-imaged on day 10. Pre- and post-flare wrist region of interest and volume. Pre- and post-flare surface distance color map demonstrating post-flare swelling (dashed arrow), not present in pre-flare image (solid arrow). Pre- and post-flare thermograms and heat distribution index (HDI). Pre- and post-flare relative frequency distributions of temperatures. SDI, surface distribution index.<p><b>Copyright information:</b></p><p>Taken from "Three-dimensional and thermal surface imaging produces reliable measures of joint shape and temperature: a potential tool for quantifying arthritis"</p><p>http://arthritis-research.com/content/10/1/R10</p><p>Arthritis Research & Therapy 2008;10(1):R10-R10.</p><p>Published online 23 Jan 2008</p><p>PMCID:PMC2374475.</p><p></p

Changes in three-dimensional and thermal measurements after intra-articular steroid injection

A 9-year-old female with polyarticular juvenile idiopathic arthritis underwent imaging before and 5 days after an intra-articular steroid injection of the left wrist. Pre- and post-injection wrist region of interest and volume with dorsal (solid white arrow) and lateral (dashed white arrow) swelling evident in the pre-injection image. Pre- and post-injection surface distance color map demonstrating pre-injection swelling (solid arrows) that resolves post-injection (dashed arrows). Pre- and post-injection thermograms and heat distribution index (HDI). Pre- and post-injection relative frequency distributions of temperatures. SDI, surface distribution index.<p><b>Copyright information:</b></p><p>Taken from "Three-dimensional and thermal surface imaging produces reliable measures of joint shape and temperature: a potential tool for quantifying arthritis"</p><p>http://arthritis-research.com/content/10/1/R10</p><p>Arthritis Research & Therapy 2008;10(1):R10-R10.</p><p>Published online 23 Jan 2008</p><p>PMCID:PMC2374475.</p><p></p

Sensitivity of three-dimensional measures to change due to simulated swelling

Various amount of clay (depicted in yellow) were added to a mannequin wrist and 2nd-5th metacarpalphalangeal (MCP) regions to represent swelling . The clay volume was estimated by forming the clay into a cube and measuring the length, width, and height with calipers. Different shapes of the same volume were used to simulate focal and diffuse swelling. Volume changes and surface distribution index (SDI) changes due to addition of clay are shown, with vertical bars representing the mean and standard deviation of three models. The dotted lines correspond to baseline volume and SDI. Large brackets encompass all values significantly greater than baseline. Small brackets represent comparison of focal and diffuse swelling measurements. *< 0.05; < 0.01; < 0.001.<p><b>Copyright information:</b></p><p>Taken from "Three-dimensional and thermal surface imaging produces reliable measures of joint shape and temperature: a potential tool for quantifying arthritis"</p><p>http://arthritis-research.com/content/10/1/R10</p><p>Arthritis Research & Therapy 2008;10(1):R10-R10.</p><p>Published online 23 Jan 2008</p><p>PMCID:PMC2374475.</p><p></p