Contemporary Problems in Combustion—Fuels, Their Valorisation, Emissions, Flexibility and Auxiliary Systems

This Special Issue is dedicated to the XXIV Symposium on Combustion Processes (23–25 September 2019, Wrocław, Poland), which is an official symposium of the Polish Section of the Combustion Institute that takes place every two years [...

Race-Specific and Skin of Color Dermatoscopic Characteristics of Skin Cancer: A Literature Review

Introduction: Individuals with melanin-rich skin account for the majority of the world's population. However, literature data regarding dermoscopic characteristics of skin cancer in skin of color (SoC) are scarce. The dermoscopic characteristics of cutaneous tumors might differ among skin types due to heterogeneity in composition and pigmentation. Objectives: To summarize literature data on the dermoscopic findings of skin neoplasms according to the skin color and race. Methods:  The literature search was performed using the PubMed database up to December 30, 2022, and was conducted with the use of terms referring to dermoscopy, race (Caucasians, Hispanics, Asians, and Black/African), and skin cancer types (basal cell carcinoma [BCC], squamous cell carcinoma [SCC], keratoacanthoma, Bowen disease, and melanoma). Results: In total, 30 race-specific records were included. Nine SoC records for BCCs (2 BCC studies in Hispanics, 1 BCC study in Black individuals, and 6 BCC studies in Asians), 9 SoC records for SCCs ( 1 SCC study in Hispanics ,1 SCC study in Black individuals and 7 SCCs in Asian population), and 8 SoC records for melanoma (2 melanoma studies in Hispanics, 1  in Blacks, and 5  in Asians) were compared with 4 records that involved only a Caucasian population, according to their participant section as well as with studies on dermoscopy characteristics without focusing on race origins and phototype of the patient. Conclusion: Based on a review of studies including Caucasians, Hispanics, Asians and Blacks /Africans, SoC patients present with more frequent and unique dermatoscopy features of skin cancers.

Report on comparison among current industrial scale lignite drying technologies

Lignite constitutes a major energy source and has long been used for energy production despite its contribution in greenhouse gas (GHG) emissions, as a fossil fuel. For example, 27.4% of Germany’s electricity originates from lignite power plants, while in Greece more than 55% of its electric energy consumption is provided by lignite. 45% of the total global coal reserves consist of low-rank coals (LRCs) such as lignite. With this background, the utilization of lignite for energy production is expected to remain a common practice in the decades to come since the availability of lignite is considerable in many countries of Europe and the world (e.g. Germany, Poland, Greece, USA, and Australia). Therefore, problems regarding the combustion and use of lignite should be addressed in a more efficient and environmentally friendly way. One of the main existing problems is the high moisture contained in raw lignite as received from the mine. The high moisture content results in higher CO2 emissions per unit of energy produced and is responsible for high capital and transport costs as well as other technical problems such as reduction in coal friability and difficulties in its blending and pneumatic transportation. Therefore, processing of lignite through drying is considered of great interest in the implementation of energy production in lignite power plants. Taking into account the significance of the subject and the usefulness of such an attempt, an overview of the currently existing drying technologies, including both evaporative and non-evaporative drying methods is reported in the present paper

Vitamin D and basal cell carcinoma: the role of oxidative stress

UV radiation (UVR) is responsible for inducing both harmful and beneficial effects on skin health. Specifically, it has been reported to disrupt oxidant and antioxidant levels, leading to oxidative stress conditions in skin tissue. This phenomenon might trigger photo-carcinogenesis, resulting in melanoma, NMSC (non-melanoma skin cancer), such as BCC (basal cell carcinoma) and SCC (squamous cell carcinoma), and actinic keratosis. On the other hand, UVR is essential for the production of adequate vitamin D levels, a hormone with important antioxidant, anticancer and immunomodulatory properties. The exact mechanisms implicated in this two-fold action are not well understood, as there still no clear relation established between skin cancer and vitamin D status. Oxidative stress seems to be a neglected aspect of this complex relation, despite its role in both skin cancer development and vitamin D deficiency. Therefore, the aim of the present study is to examine the correlation between vitamin D and oxidative stress in skin cancer patients. A total of 100 subjects (25 with SCC, 26 with BCC, 23 with actinic keratosis, and 27 controls) were assessed in terms of 25-hydroxyvitamin D (25(OH) D) and redox markers such as thiobarbituric acid reactive substances (TBARS), protein carbonyls, total antioxidant capacity (TAC) in plasma, glutathione (GSH) levels and catalase activity in erythrocytes. The majority of our patients revealed low vitamin D levels; 37% of the subjects showed deficiency (<20 ng/mL) and 35% insufficiency (21–29 ng/mL). The mean 25(OH) D level of the NMSC patients (20.87 ng/mL) was also found to be significantly lower (p = 0.004) than that of the non-cancer patients (28.14 ng/mL). Furthermore, higher vitamin D levels were also correlated with lower oxidative stress (positive correlation with GSH, catalase activity TAC index and negative correlation with TBARS and CARBS indices). NMSC patients diagnosed with SCC showed lower catalase activity values compared to non-cancer patients (p < 0.001), with the lowest values occurring in patients with a chronic cancer diagnosis (p < 0.001) and vitamin D deficiency (p < 0.001). Higher GSH levels (p = 0.001) and lower TBARS levels (p = 0.016) were found in the control group compared to the NMSC group, and to patients with actinic keratosis. Higher levels of CARBS were observed in patients with SCC (p < 0.001). Non-cancer patients with vitamin D sufficiency showed higher TAC values compared to non-cancer patients with vitamin D deficiency (p = 0.023) and to NMSC patients (p = 0.036). The above-mentioned results indicate that NMSC patients reveal increased levels of oxidative damage markers compared to control levels, while vitamin D status plays a critical role in the determination of individuals’ oxidative status.Το βασικοκυτταρικό καρκίνωμα αποτελεί τη κυρίαρχη μορφή καρκίνου δέρματος καθώς επίσης κατέχει κι από τις πρώτες θέσεις στη συχνότητα εμφάνισης ανάμεσα σε άλλες μορφές καρκίνου. Από την άλλη πλευρά, η βιταμίνη του ήλιου ή αλλιώς η βιταμίνη D, παράγεται από τον οργανισμό όταν η ηλιακή ακτινοβολία έρθει σε επαφή με το δέρμα. Η συγκεκριμένη βιταμίνη - ορμόνη, φαίνεται ότι σε χαμηλές συγκεντρώσεις μπορεί να οδηγήσει στην εμφάνιση οξειδωτικού στρες που αυξάνει την πιθανότητα βλαβών στο DNA προκαλώντας καρκινογέννηση. Η παρούσα μελέτη αποτελεί την πρώτη μελέτη που επικεντρώνεται σε αυτή τη τριπλή σχέση: καρκίνος δέρματος, βιταμίνης D και οξειδωτικού στρες

Pustular Eruption following COVID-19 Vaccination: A Narrative Case-Based Review

From the beginning of public vaccinations until the relaxation of COVID-19 measures, many case reports, case series and case–control studies have been published indicating cutaneous side effects of COVID-19 vaccination. Post-vaccination pustular eruption was reported as well, with a challenging differential diagnosis between pustular psoriasis, AGEP (acute generalized exanthematous pustulosis) and neutrophil pustular eruptions. We report a case of 56-year-old woman presented with acute generalized pustular flare up culminated 5 days after the second dose of BNT162b2(Pfizer) vaccination. She was diagnosed with pustular psoriasis flare and due to the regulating role of IL-1 in pustular psoriasis and in the cytokine storm observed in cases of COVID-19 postvaccination inflammation; we decided to treat the patient with an IL-1 antagonist, subcutaneous anakinra (100 mg daily) along with acitretin. One week later, after anakinra withdrawal, she presented a pustular psoriasis flare and a 7-day anakinra re-administration led to a satisfactory improvement in the skin lesions. We also reviewed the medical literature and found 28 case reports with pustular eruption after the COVID-19 vaccination. We compared the patients reported, regarding sex, age, number of doses, post-vaccination period and vaccine brand, and compared those results with our patient. Finally, as indicated by our case and other cases with similarly treated pustular eruptions. targeted therapy to this cytokine imbalance such as anakinra (IL-1) antagonist can improve the clinical course of the patient

Drying of Lignite of Various Origins in a Pilot Scale Toroidal Fluidized Bed Dryer using Low Quality Heat

An experimental study was carried out for lignites of different places of origin, i.e., Poland, Greece, Romania and Australia, using a toroidal bed dryer. The effect of the temperature on the drying efficiency, including the loss of moisture content over time under fixed drying conditions was the subject of the investigation. The main goal was to confirm the possibility of the use of a toroidal bed as a base for a drying system that could utilize low quality heat from sources such as flue gases from a boiler and determine the optimum parameters for such a system. The conducted study has conclusively proven the feasibility of the use of low temperature heat sources for drying lignite in a toroidal bed. A moisture content of 20% could be achieved for most of the tested lignites, using the toroidal bed, with reasonably short residence times (approx. 30 min) and an air temperature as low as 60 &#176;C. Moreover, the change of the particle size distribution, to some degree, affected the final moisture content due to the entrainment of wet, fine particles. The study also determined that the in-bed attrition of the particles is partially responsible for the generation of fines