Resilience: the big picture - top themes and trends

This report uses infographics to identify the key themes and emerging trends in resilience thinking and practice. The report includes sections on: // The rise in the use of the term 'resilience' in books, scholarly journals and scientific research across a range of disciplines; // The salience of different themes within resilience thinking; Identification of geographies of resilience: by pinpointing the countries of author affiliation, and the regions studied in resilience literature; // Examination of resilience on Twitter: looking at key themes and trends most frequently used in relation to ‘resilience’; // Analysis of the characteristics of resilience: looking at the way in which academic and grey literature explore awareness, diversity, self-regulation, integration and adaptiveness; // Inclusion of resilience in the post-2015 agenda, including the Sendai Framework for Disaster Risk Reduction 2015-2030 (SFDRR), the Sustainable Development Goals (SDGs), and the UNFCCC COP21 Paris Agreement on climate change

Resilience in the SDGs: Developing an indicator for Target 1.5 that is fit for purpose

An appropriate indicator for target 1.5 is needed. This paper provides one proposal as a first step to stimulate further debate. We outline a comprehensive approach for developing a cross-sectoral, multi-dimensional and dynamic understanding of resilience. This underpins the core message of the Sustainable Development Goals (SDGs) that development is multi-faceted and the achievement of many of the individual development goals is dependent on the accomplishment of other goals. It also acknowledges that shocks and stresses can reverse years of development gains and efforts to eradicate poverty by 2030. Crucially, this approach to understanding resilience draws on data that countries will collect for the SDGs anyway and entails only a small additional burden in this regard

Grid-Connected Energy Storage Systems: State-of-the-Art and Emerging Technologies

High penetration of renewable energy resources in the power system results in various new challenges for power system operators. One of the promising solutions to sustain the quality and reliability of the power system is the integration of energy storage systems (ESSs). This article investigates the current and emerging trends and technologies for grid-connected ESSs. Different technologies of ESSs categorized as mechanical, electrical, electrochemical, chemical, and thermal are briefly explained. Especially, a detailed review of battery ESSs (BESSs) is provided as they are attracting much attention owing, in part, to the ongoing electrification of transportation. Then, the services that grid-connected ESSs provide to the grid are discussed. Grid connection of the BESSs requires power electronic converters. Therefore, a survey of popular power converter topologies, including transformer-based, transformerless with distributed or common dc-link, and hybrid systems, along with some discussions for implementing advanced grid support functionalities in the BESS control, is presented. Furthermore, the requirements of new standards and grid codes for grid-connected BESSs are reviewed for several countries around the globe. Finally, emerging technologies, including flexible power control of photovoltaic systems, hydrogen, and second-life batteries from electric vehicles, are discussed in this article.This work was supported in part by the Office of Naval Research Global under Grant N62909-19-1-2081, in part by the National Research Foundation of Singapore Investigatorship under Award NRFI2017-08, and in part by the I2001E0069 Industrial Alignment Funding. (Corresponding author: Josep Pou.

Two alternative methods for the retrieval of somatic cell populations from the mouse ovary

Many modern techniques employed to uncover the molecular fundamentals underlying biological processes require dissociated cells as their starting point/substrate. Investigations into ovarian endocrinology or folliculogenesis therefore necessitate robust protocols for dissociating the ovary into its constituent cell populations. While in the mouse, methods to obtain individual, mature follicles are well-established, the separation and isolation of single cells of all types from early mouse follicles, including somatic cells, has been more challenging. Herein we present two methods for the isolation of somatic cells in the ovary. These methods are suitable for a range of applications relating to the study of folliculogenesis and mouse ovarian development. First, an enzymatic dissociation utilising collagenase and a temporary, primary cell culture step using neonatal mouse ovaries which yields large quantities of granulosa cells from primordial, activating, and primary follicles. Second, a rapid papain dissociation resulting in a high viability single cell suspension of ovarian somatic cells in less than an hour, which can be applied from embryonic to adult ovarian samples. Collectively these protocols can be applied to a broad array of investigations with unique advantages and benefits pertaining to both

The Triple Dividend of Resilience—A New Narrative for Disaster Risk Management and Development

To secure development gains and help eradicate poverty in the long run, it is critical to strengthen ex-ante disaster risk management (DRM) measures that build resilience at the household, firm and macro level. Decision-makers however often view DRM investments as a gamble that pays off only in the event of a disaster. This is despite increasing evidence that building resilience yields significant and tangible benefits, even if a disaster does not happen for many years. This chapter outlines the Triple Dividend of Resilience as a new analytical method to enhance the business case for investments in building resilience. The three benefits that are outlined are: (1) avoiding losses when disasters strike; (2) unlocking development potential by stimulating economic activity thanks to reduced disaster-related investment risks; and (3) social, environmental and economic co-benefits associated with investments. The second and third dividends in particular are typically overlooked in appraisals around investment decisions, and can accrue even in the absence of disaster events. Presenting evidence of additional dividends to policy-makers and investors can provide a stronger case for investment in DRM, helping to reconcile short- and long-term objectives. This chapter sets the conceptual basis for the more detailed assessments of the resilience streams and implications for decision-makers provided in the following chapters

Therapists’ experiences of remotely delivering cognitive-behavioural or graded-exercise interventions for fatigue: a qualitative evaluation

Objectives: Fatigue is a challenging feature of all inflammatory rheumatic diseases. LIFT (Lessening the Impact of Fatigue in inflammatory rheumatic diseases: a randomised Trial) included remotely delivered personalised exercise programme (PEP) or cognitive-behavioural approach (CBA) interventions. The aim of this nested qualitative evaluation was to understand rheumatology health professionals (therapists’) perspectives of delivering the interventions in the LIFT trial. Methods: A subgroup of therapists who had delivered the PEP and CBA interventions took part in semi-structured telephone interviews. Results: Seventeen therapists (13 women, 4 men) who delivered PEP (n = 8) or CBA (n = 9) interventions participated. Five themes were identified: In ‘The benefits of informative, structured training’, therapists described how they were able to practice their skills, and the convenience of having the LIFT manual to refer to. When ‘Getting into the swing of it’, supporting patients gave therapists the confidence to tailor the content of the manual to each patient. Clinical supervision supported therapists to gain feedback and request assistance when required. In ‘Delivering the intervention’ therapists reported that patients valued the opportunity to address their fatigue and challenge their own beliefs. ‘Challenges in delivering the LIFT intervention’ therapists struggled to work collaboratively with patients who lacked motivation or stopped engaging. Finally, ‘Lift developing clinical skills’ therapists gained confidence and professional satisfaction seeing patients’ fatigue improve. Conclusion: Findings support the value of skills training for rheumatology health professionals to deliver a remote fatigue management intervention tested in the LIFT trial. These insights can inform service provision and clinical practice Lay summary What does this mean for patients ? Fatigue can be a challenge in inflammatory rheumatic diseases (IRDs). The LIFT study (Lessening the Impact of Fatigue in inflammatory rheumatic diseases: a randomized Trial) explored interventions to support people with fatigue. These were: a cognitive-behavioural approach (CBA), a personalized exercise programme (PEP), or usual care. People with IRDs were chosen randomly to take part in seven sessions of CBA, seven sessions of PEP or usual care. All sessions (aside from the first PEP session) were delivered over the phone. The aim of this study was to explore therapists' experiences of delivering the intervention. Seventeen therapists (13 women and 4 men) took part; eight had delivered the PEP intervention, and 9 delivered the CBA intervention. Therapists who delivered LIFT told us they enjoyed the chance to practice their skills, and that the LIFT manual gave them the confidence to tailor the intervention to each patient. Clinical supervision was valued. Therapists also shared that LIFT improved their skills and they were happy to see patients' fatigue improve over time. These new results can inform clinical practice, and how services are provided

Climate change, conflict and fragility : information and analysis to support programme design scoping for the climate and resilience framework programme (CLARE)

This in-depth paper provides important resource links and references regarding approaches to ensuring that climate change programming and policies in fragile and conflict-affected contexts do not exacerbate conflict. It examines evidence gaps in addition to what is known, from multiple disciplinary perspectives, including disaster risk reduction (DRR), conflict sensitivity, climate adaptation and conflict and humanitarian research and programmes. Regarding funding, design and delivery of programmes, programming for uncertainty (in relation to both conflict dynamics and climate change) should be built into the funding set-up. Proper climate analysis, including attribution and sensitivity analysis, continues to be lacking in many climate-conflict studies.UK Department for International Development (DFID

Randomised, double-blind, multicentre, mixed-methods, dose-escalation feasibility trial of mirtazapine for better treatment of severe breathlessness in advanced lung disease (BETTER-B feasibility)

© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY. Published by BMJ. New treatments are required for severe breathlessness in advanced disease. We conducted a randomised feasibility trial of mirtazapine over 28 days in adults with a modified medical research council breathlessness scale score ≥3. Sixty-four patients were randomised (409 screened), achieving our primary feasibility endpoint of recruitment. Most patients had COPD or interstitial lung disease; 52 (81%) completed the trial. There were no differences between placebo and mirtazapine in tolerability or safety, and blinding was maintained. Worst breathlessness ratings at day 28 (primary clinical activity endpoint) were, 7.1 (SD 2.3, placebo) and 6.3 (SD 1.8, mirtazapine). A phase III trial of mirtazapine is indicated. Trial registration: ISRCTN 32236160; European Clinical Trials Database (EudraCT no: 2015-004064-11)