More on Phantom Bidding

A phantom bidding model is analyzed for a sale auction. The following questions are addressed: the effects of phantom bidding on overall social welfare and buyers' profits. It is shown that social welfare may increase or decrease as the auctioneer switches from the fixed reserve price policy to phantom bidding. The buyers' profits will increase whenever social welfare increases.English Auction, Phantom Bidding, Fixed/Flexible Reserve Price

Uma crítica à infância medicalizada e judicializada pelo UNICEF / A criticism of children medicated and judicialized by UNICEF

Este artigo visa problematizar as práticas de medicalização e judicialização da vida de crianças e adolescentes brasileiras pelo Fundo das Nações Unidas para a Infância (UNICEF), no presente. Esta proposta é parte de pesquisas realizadas, ao longo dos últimos anos, no Brasil, sob financiamento do CNPQ. Alguns resultados dos estudos documentais e históricos realizados são abordados e analisados neste artigo com o recorte dos mecanismos denominados de medicalização e judicialização dos corpos e das subjetividades no contemporâneo. O UNICEF materializa práticas de promoção, defesa e garantia de direitos que estão sustentadas por racionalidades médico-psicológicas, biomédicas e jurídico-assistenciais baseadas em pressupostos de saber e de poder disciplinares, biopolíticos e de segurança. Portanto, busca-se pensar a interrogação destes mecanismos e criar outros modos de ser, sentir, agir e produzir modos de viver que não fiquem presos ao modelo disciplinar, biopolítico e securitário. 

Atividades antiinflamatória, analgésica e antipirética de flavonóides isolados de plantas brasileiras

BV UNIFESP: Teses e dissertaçõe

Atividades farmacológicas de um inibidor seletivo da calicreína tecidual em processos nociceptivos e inflamatórios de camundongos

BV UNIFESP: Teses e dissertaçõe

Electrophoretic enzyme deposition on nano-structured conducting polymer substrates for high sensitivity biosensors

Performance of enzyme based biosensors directly depends on how much enzyme can be loaded onto a unit surface area of the sensor substrate, and how easily the particles under measurement reach the substrate. In the past we have developed nano-structured substrate surfaces using conducting polymer Polypyrrole (PPy) to increase the effective sensor surface area for a unit 2-D area and have developed very high enzyme adsorption using Gluteraldehyde as cross-linker [1],[2]. In this work we have developed a novel method of further improving enzyme adsorption. The enzyme was dissolved in a phosphate buffer solution and was allowed to adsorb under a high electric field

Electrophoretic enzyme deposition on nano-structured conducting polymer substrates for high sensitivity biosensors

Performance of enzyme based biosensors directly depends on how much enzyme can be loaded onto a unit surface area of the sensor substrate, and how easily the particles under measurement reach the substrate. In the past we have developed nano-structured substrate surfaces using conducting polymer Polypyrrole (PPy) to increase the effective sensor surface area for a unit 2-D area and have developed very high enzyme adsorption using Gluteraldehyde as cross-linker [1],[2]. In this work we have developed a novel method of further improving enzyme adsorption. The enzyme was dissolved in a phosphate buffer solution and was allowed to adsorb under a high electric field

Pharmacological evaluation of the antiinflammatory activity of a citrus bioflavonoid, hesperidin, and the isoflavonoids, duartin and claussequinone, in rats and mice

Pretreatment of rats with hesperidin (50 and 100 mg kg(-1), s.c.) reduced the paw oedema induced by carrageenan by 47 and 63%, respectively, within 5 h. The effect was equivalent to that produced by indomethacin (10 mg kg(-1), p.o.), although unrelated to the administered dose, particularly at high doses. At 100 mg kg(-1) hesperidin decreased the rat paw oedema induced by dextran by 33%, without influencing the histamine-induced paw oedema. Hesperidin also inhibited pleurisy induced by carrageenan, reducing the volume of exudate and the number of migrating leucocytes by 48 and 34%, respectively, of control values. Equal doses of duartin and claussequinone were ineffective in all the above tests. Pretreatment of mice with hesperidin (100 mg kg(-1), s.c.) reduced acetic acid-induced abdominal constriction by 50%, but did not affect the tail flick response. Hyperthermia induced by yeast in rats was slightly reduced by hesperidin. No lesions of the gastric mucosae were detected in rats pretreated with hesperidin. The results indicate that hesperidin obtained from citrus cultures may present a potential therapeutical use as a mild antiinflammatory agent, being also useful as a precursor of new flavonoids endowed with such activity.ESCOLA PAULISTA MED,DEPT PHARMACOL,NAT PROD SECT,BR-04044020 SAO PAULO,SP,BRAZILUNIV FED MINAS GERAIS,SCH PHARM,BELO HORIZONT,MG,BRAZILESCOLA PAULISTA MED,DEPT PHARMACOL,NAT PROD SECT,BR-04044020 SAO PAULO,SP,BRAZILWeb of Scienc