91 research outputs found

    Research on four drilling and sampling methods for groundwater up to five metres below groundwater level in sandy areas

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    NB Klik hier voor de zip file met Bijlage 11: Analyseresultaten en veldgegevens ronde 1 t/m 3 De zogeheten Multi-Channel Well (MCW) geplaatst met de SonicSampDrill blijkt de beste methode te zijn om het grondwater bij landbouwbedrijven tot vijf meter onder de grondwaterspiegel te analyseren. Dat komt vooral doordat deze methode in staat is om tot die diepte met een machinale trilboring meerdere monsternemingsfilters te plaatsen. Daardoor zijn minder boorgaten nodig. Momenteel wordt bij landbouwbedrijven de grondwaterkwaliteit gemeten in de bovenste meter van het grondwater. Met die metingen, uitgevoerd binnen het Landelijk Meetnet Effecten Mestbeleid (LMM) worden effecten van het mestbeleid op de grondwaterkwaliteit onderzocht; die effecten weerspiegelen zich in de bovenste meter. Daarnaast worden deze metingen gebruikt om de grondwaterkwaliteit te toetsen aan de nitraatnorm. Momenteel wordt onderzocht of de toetsdiepte voor nitraat verlaagd kan worden naar vijf meter. Ten eerste omdat de Europese regelgeving daar ruimte voor lijkt te bieden. Ten tweede omdat nitraatconcentraties dieper in de bodem kunnen afnemen. Hierdoor wordt nu mogelijk te streng getoetst. Met de LMM-methode kan echter niet zo diep geboord worden. Mocht de toetsdiepte worden verlaagd, dan is dus een andere monsternemingsmethode vereist. Het RIVM heeft vier methoden onderzocht. Het onderzoek is uitgevoerd op zestien boorlocaties bij vier melkveehouderijbedrijven verspreid over de vier grote zandgebieden in Nederland (Noord, Oost, Centraal en Zuid). De onderzochte methoden kenmerken zich onder andere door handmatig of machinaal boren en door de installatie van tijdelijke of permanente filters. De methoden zijn beoordeeld op hun praktische inzetbaarheid en op de kwaliteit van de monsterneming. Zo blijkt de handmatige Van der Staay-methode, die tijdelijke filters plaatst, slechts op vijftig procent van de locaties op de gewenste diepte te kunnen komen. Met de machinale Uitschuifbare Punt-methode, die ook tijdelijke filters plaatst, is het boren en het verzamelen van watermonsters in de praktijk niet goed te combineren. Bij de MCW en de Direct Well-methode (DW) worden na machinale boring permanente filters geplaatst. In tegenstelling tot de MCW heeft de DW daarbij voor ieder filter een apart boorgat nodig.The so-called Multi-Channel Well (MCW), installed using the SonicSampDrill, has proven to be the best method for analysing groundwater on farms up to five metres below groundwater level. This is because this method - using just one sonic drilling allows placement of multiple sampling filters up to five metres below this level, so fewer boreholes are needed. At the moment, groundwater quality on farms in the Netherlands is measured in the uppermost one metre of the groundwater. These measurements, carried out in the framework of the Netherlands National Monitoring Programme for Effectiveness of the Minerals Policy (LLM in Dutch) are used to determine effects of the fertiliser policy on the groundwater quality; effects are reflected in the topmost metre. Besides this, measurements are also used to test the groundwater quality against the nitrate standard. At the moment it is being investigated if the test depth can be lowered to five metres. First of all, because this seems to be in line with the European regulations. And secondly, because concentrations of nitrate deeper in the soil can decrease. This involves the possibility of too stringent testing at the moment. However, the LMM method does not allow such deep drilling, so a lower test depth will require another drilling and sampling method. RIVM has investigated four methods at four dairy farms. These dairy farms are spread across the four large sandy areas in the Netherlands (north, east, centre and south). Every farm contains four drilling sites, totalling 16. The methods investigated are characterised, for example, by hand or machine drilling and by the installation of temporary or permanent filters. Methods are assessed on practical application and the quality of the sampling. With the manual Van der Staay method, in which temporary filters are installed, the desired depth is achieved at only 50 per cent of the sites. With the use of the mechanised Extendable Point Method, in which temporary filters are placed too, drilling and water sampling forms a poor combination in practice. The MCW and the Direct Well (DW) methods allow placement of permanent filters after machine drilling. Contrary to the MCW method, the DW method requires a separate borehole for each filter.VROMLN

    IOB Review - Riding the wave of sustainable commodity sourcing. Review of the Sustainable Trade Initiative IDH 2008-2013

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    The Sustainable Trade Initiative IDH (Initiatief Duurzame Handel) was set up in 2008 as a multi-stakeholder initiative of private companies, non-governmental organisations (NGOs), trade unions and the Dutch government with the aim of improving smallholder production systems, market integration and enhancing sustainable sourcing from developing countries. The activities undertaken by IDH focused on improving and transforming the supply chain performance of internationally traded commodities (such as coffee, tea, cotton, cocoa, timber, palm oil and fish). They rely on promoting good agricultural practice, farmers’ training and certification as key activities

    Socioeconomic determinants of organic cotton adoption in Benin, West Africa

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    Organic cotton relies on ecological processes and the use of natural resources to sustain the production system, unlike conventional cotton, mainly characterized by massive utilization of synthesis chemicals. In West Africa, where rural livelihoods are particularly vulnerable, organic cotton is expected to contribute not only to poverty reduction but also to strengthen households’ resilience. The objective of this study was to assess institutional and socioeconomic factors determining farmers’ decisions to adopt organic cotton. For this purpose, we applied a probit model on empirical data collected from producers of the Centre and the Northern parts of Benin. Overall, we found that organic cotton adoption is mainly determined by farmers’ socioeconomic characteristics, the physical distance between farm and house, and contact with extension and advisory services. Organic farming is more attractive to women compared to conventional farming. This because such type of cotton farming enables women to hold a separate cotton farm and thus increase their economic independence, whereas with the conventional system they depend mainly on the farm of the (male) head of the household. Older, less educated and low-income farmers who express environmental concern are more likely to adopt organic cotton. Subsequently, organic cotton should be considered as a prospective policy option to reach the poor and strengthen their livelihoods conditions while contributing to preserve the environment and natural resources. Furthermore, farmers who have their farm near home are more likely to adopt organic farming than those who have the farm far from their home. It also came out that organic farmers have more contacts with advisory and extension services. Finally, the study noted that there is still a need to enhance the extension system by: (1) exploring, designing, and upgrading innovative pedagogic tools such as videos and mobile phone technology to foster learning; and (2) strengthening organic farmer’s organizations and the linkage with agricultural research organizations for technology development

    Molecular characteristics of carbapenemase-producing Enterobacterales in the Netherlands; results of the 2014–2018 national laboratory surveillance

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    Objectives: Carbapenem resistance mediated by mobile genetic elements has emerged worldwide and has become a major public health threat. To gain insight into the molecular epidemiology of carbapenem resistance in The Netherlands, Dutch medical microbiology laboratories are requested to submit suspected carbapenemase-producing Enterobacterales (CPE) to the National Institute for Public Health and the Environment as part of a national surveillance system. Methods: Meropenem MICs and species identification were confirmed by E-test and MALDI-TOF and carbapenemase production was assessed by the Carbapenem Inactivation Method. Of all submitted CPE, one species/carbapenemase gene combination per person per year was subjected to next-generation sequencing (NGS). Results: In total, 1838 unique isolates were received between 2014 and 2018, of which 892 were unique CPE isolates with NGS data available. The predominant CPE species were Klebsiella pneumoniae (n = 388, 43%), Escherichia coli (n = 264, 30%) and Enterobacter cloacae complex (n = 116, 13%). Various carbapenemase alleles of the same carbapenemase gene resulted in different susceptibilities to meropenem and this effect varied between species. Analyses of NGS data showed variation of prevalence of carbapenemase alleles over time with blaOXA-48 being predominant (38%, 336/892), followed by blaNDM-1 (16%, 145/892). For the first time in the Netherlands, blaOXA-181, blaOXA-232 and blaVIM-4 were detected. The genetic background of K. pneumoniae and E. coli isolates was highly diverse. Conclusions: The CPE population in the Netherlands is diverse, suggesting multiple introductions. The predominant carbapenemase alleles are blaOXA-48 and blaNDM-1. There was a clear association between species, carbapenemase allele and susceptibility to meropenem

    National laboratory-based surveillance system for antimicrobial resistance: a successful tool to support the control of antimicrobial resistance in the Netherlands

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    An important cornerstone in the control of antimicrobial resistance (AMR) is a well-designed quantitative system for the surveillance of spread and temporal trends in AMR. Since 2008, the Dutch national AMR surveillance system, based on routine data from medical microbiological laboratories (MMLs), has developed into a successful tool to support the control of AMR in the Netherlands. It provides background information for policy making in public health and healthcare services, supports development of empirical antibiotic therapy guidelines and facilitates in-depth research. In addition, participation of the MMLs in the national AMR surveillance network has contributed to sharing of knowledge and quality improvement. A future improvement will be the implementation of a new semantic standard together with standardised data transfer, which will reduce errors in data handling and enable a more real-time surveillance. Furthermore, the

    Group B streptococcus serotype prevalence in reproductive-age women at a tertiary care military medical center relative to global serotype distribution

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    <p>Abstract</p> <p>Background</p> <p>Group B <it>Streptococcus </it>(GBS) serotype (Ia, Ib, II-IX) correlates with pathogen virulence and clinical prognosis. Epidemiological studies of seroprevalence are an important metric for determining the proportion of serotypes in a given population. The purpose of this study was to evaluate the prevalence of individual GBS serotypes at Madigan Healthcare System (Madigan), the largest military tertiary healthcare facility in the Pacific Northwestern United States, and to compare seroprevalences with international locations.</p> <p>Methods</p> <p>To determine serotype distribution at Madigan, we obtained GBS isolates from standard-of-care anogenital swabs from 207 women of indeterminate gravidity between ages 18-40 during a five month interval. Serotype was determined using a recently described molecular method of polymerase chain reaction by capsular polysaccharide synthesis (cps) genes associated with pathogen virulence.</p> <p>Results</p> <p>Serotypes Ia, III, and V were the most prevalent (28%, 27%, and 17%, respectively). A systematic review of global GBS seroprevalence, meta-analysis, and statistical comparison revealed strikingly similar serodistibution at Madigan relative to civilian-sector populations in Canada and the United States. Serotype Ia was the only serotype consistently higher in North American populations relative to other geographic regions (p < 0.005). The number of non-typeable isolates was significantly lower in the study (p < 0.005).</p> <p>Conclusion</p> <p>This study establishes PCR-based serotyping as a viable strategy for GBS epidemiological surveillance. Our results suggest that GBS seroprevalence remains stable in North America over the past two decades.</p

    Use of the WHO Access, Watch, and Reserve classification to define patterns of hospital antibiotic use (AWaRe): an analysis of paediatric survey data from 56 countries

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    BACKGROUND: Improving the quality of hospital antibiotic use is a major goal of WHO's global action plan to combat antimicrobial resistance. The WHO Essential Medicines List Access, Watch, and Reserve (AWaRe) classification could facilitate simple stewardship interventions that are widely applicable globally. We aimed to present data on patterns of paediatric AWaRe antibiotic use that could be used for local and national stewardship interventions. METHODS: 1-day point prevalence survey antibiotic prescription data were combined from two independent global networks: the Global Antimicrobial Resistance, Prescribing, and Efficacy in Neonates and Children and the Global Point Prevalence Survey on Antimicrobial Consumption and Resistance networks. We included hospital inpatients aged younger than 19 years receiving at least one antibiotic on the day of the survey. The WHO AWaRe classification was used to describe overall antibiotic use as assessed by the variation between use of Access, Watch, and Reserve antibiotics, for neonates and children and for the commonest clinical indications. FINDINGS: Of the 23 572 patients included from 56 countries, 18 305 were children (77·7%) and 5267 were neonates (22·3%). Access antibiotic use in children ranged from 7·8% (China) to 61·2% (Slovenia) of all antibiotic prescriptions. The use of Watch antibiotics in children was highest in Iran (77·3%) and lowest in Finland (23·0%). In neonates, Access antibiotic use was highest in Singapore (100·0%) and lowest in China (24·2%). Reserve antibiotic use was low in all countries. Major differences in clinical syndrome-specific patterns of AWaRe antibiotic use in lower respiratory tract infection and neonatal sepsis were observed between WHO regions and countries. INTERPRETATION: There is substantial global variation in the proportion of AWaRe antibiotics used in hospitalised neonates and children. The AWaRe classification could potentially be used as a simple traffic light metric of appropriate antibiotic use. Future efforts should focus on developing and evaluating paediatric antibiotic stewardship programmes on the basis of the AWaRe index. FUNDING: GARPEC was funded by the PENTA Foundation. GARPEC-China data collection was funded by the Sanming Project of Medicine in Shenzhen (SZSM2015120330). bioMérieux provided unrestricted funding support for the Global-PPS
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