1,218 research outputs found

    Mendel’s journey to Paris and London: context and significance for the origin of genetics.

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    From a letter Gregor Mendel wrote to his brother-in-law, and a photograph of a large group of people in Paris, it is known that Mendel visited the International Exhibition in London in August 1862. There has been speculation about the status and composition of this travel group; for example, whether it was an official delegation from the city of Brünn. There has also been speculation on whether Mendel visited Charles Darwin on that occasion. We have now found a partial list of participants of the second 1862 pleasure train (Vergnügungszug) from Vienna to Paris and London, which includes Mendel’s name. The names of 158 participants make a partial reconstruction of the travel group possible. Digital newspapers were researched to get more insight into the status, residence, and profession of the participants. Most belonged to the upper-class of the Austrian Empire, among them several citizens of Brünn. Such luxurious all-inclusive pleasure trains were a new phenomenon in Vienna at the time and received much attention in the newspapers. Gregor Mendel was one of the first to participate in this expensive new trend. The person next to Mendel in the photograph shows a clear resemblance with Johann Nave in the photograph of the founding members of the Natural Science Society of Brünn the same year (see Figs. 1 and 5). The newspaper lists of arrivals in Viennese hotels shows that Johann Nave, was in Vienna when the pleasure train departed. Johann Nave was an internationally acknowledged algae expert with interest in plant reproductive processes. In 1858 Mendel had nominated Nave as a new member of the scientific section of the Agricultural Society. A scientific connection between Mendel and Nave has been conjectured previously; however, evidence was lacking so far. After his early death in 1864, Nave’s scientific library was acquired by the Natural Science Society. It contained books about the latest insights on plant fertilization, and since Mendel’s 1866-paper contains a lengthy footnote about this topic, Mendel and Nave likely discussed this area of Mendel’s research. This may also have been the case during their journey to Paris and London because it was in 1862 that Mendel conducted the final crossing experiments to test his hypothesis about the composition and the random union of pollen and egg cells

    Mendel’s journey to Paris and London: context and significance for the origin of genetics.

    Get PDF
    From a letter Gregor Mendel wrote to his brother-in-law, and a photograph of a large group of people in Paris, it is known that Mendel visited the International Exhibition in London in August 1862. There has been speculation about the status and composition of this travel group; for example, whether it was an official delegation from the city of Brünn. There has also been speculation on whether Mendel visited Charles Darwin on that occasion. We have now found a partial list of participants of the second 1862 pleasure train (Vergnügungszug) from Vienna to Paris and London, which includes Mendel’s name. The names of 158 participants make a partial reconstruction of the travel group possible. Digital newspapers were researched to get more insight into the status, residence, and profession of the participants. Most belonged to the upper-class of the Austrian Empire, among them several citizens of Brünn. Such luxurious all-inclusive pleasure trains were a new phenomenon in Vienna at the time and received much attention in the newspapers. Gregor Mendel was one of the first to participate in this expensive new trend. The person next to Mendel in the photograph shows a clear resemblance with Johann Nave in the photograph of the founding members of the Natural Science Society of Brünn the same year (see Figs. 1 and 5). The newspaper lists of arrivals in Viennese hotels shows that Johann Nave, was in Vienna when the pleasure train departed. Johann Nave was an internationally acknowledged algae expert with interest in plant reproductive processes. In 1858 Mendel had nominated Nave as a new member of the scientific section of the Agricultural Society. A scientific connection between Mendel and Nave has been conjectured previously; however, evidence was lacking so far. After his early death in 1864, Nave’s scientific library was acquired by the Natural Science Society. It contained books about the latest insights on plant fertilization, and since Mendel’s 1866-paper contains a lengthy footnote about this topic, Mendel and Nave likely discussed this area of Mendel’s research. This may also have been the case during their journey to Paris and London because it was in 1862 that Mendel conducted the final crossing experiments to test his hypothesis about the composition and the random union of pollen and egg cells

    Mendel’s journey to Paris and London: context and significance for the origin of genetics.

    Get PDF
    From a letter Gregor Mendel wrote to his brother-in-law, and a photograph of a large group of people in Paris, it is known that Mendel visited the International Exhibition in London in August 1862. There has been speculation about the status and composition of this travel group; for example, whether it was an official delegation from the city of Brünn. There has also been speculation on whether Mendel visited Charles Darwin on that occasion. We have now found a partial list of participants of the second 1862 pleasure train (Vergnügungszug) from Vienna to Paris and London, which includes Mendel’s name. The names of 158 participants make a partial reconstruction of the travel group possible. Digital newspapers were researched to get more insight into the status, residence, and profession of the participants. Most belonged to the upper-class of the Austrian Empire, among them several citizens of Brünn. Such luxurious all-inclusive pleasure trains were a new phenomenon in Vienna at the time and received much attention in the newspapers. Gregor Mendel was one of the first to participate in this expensive new trend. The person next to Mendel in the photograph shows a clear resemblance with Johann Nave in the photograph of the founding members of the Natural Science Society of Brünn the same year (see Figs. 1 and 5). The newspaper lists of arrivals in Viennese hotels shows that Johann Nave, was in Vienna when the pleasure train departed. Johann Nave was an internationally acknowledged algae expert with interest in plant reproductive processes. In 1858 Mendel had nominated Nave as a new member of the scientific section of the Agricultural Society. A scientific connection between Mendel and Nave has been conjectured previously; however, evidence was lacking so far. After his early death in 1864, Nave’s scientific library was acquired by the Natural Science Society. It contained books about the latest insights on plant fertilization, and since Mendel’s 1866-paper contains a lengthy footnote about this topic, Mendel and Nave likely discussed this area of Mendel’s research. This may also have been the case during their journey to Paris and London because it was in 1862 that Mendel conducted the final crossing experiments to test his hypothesis about the composition and the random union of pollen and egg cells

    Mendel’s journey to Paris and London: context and significance for the origin of genetics.

    Get PDF
    From a letter Gregor Mendel wrote to his brother-in-law, and a photograph of a large group of people in Paris, it is known that Mendel visited the International Exhibition in London in August 1862. There has been speculation about the status and composition of this travel group; for example, whether it was an official delegation from the city of Brünn. There has also been speculation on whether Mendel visited Charles Darwin on that occasion. We have now found a partial list of participants of the second 1862 pleasure train (Vergnügungszug) from Vienna to Paris and London, which includes Mendel’s name. The names of 158 participants make a partial reconstruction of the travel group possible. Digital newspapers were researched to get more insight into the status, residence, and profession of the participants. Most belonged to the upper-class of the Austrian Empire, among them several citizens of Brünn. Such luxurious all-inclusive pleasure trains were a new phenomenon in Vienna at the time and received much attention in the newspapers. Gregor Mendel was one of the first to participate in this expensive new trend. The person next to Mendel in the photograph shows a clear resemblance with Johann Nave in the photograph of the founding members of the Natural Science Society of Brünn the same year (see Figs. 1 and 5). The newspaper lists of arrivals in Viennese hotels shows that Johann Nave, was in Vienna when the pleasure train departed. Johann Nave was an internationally acknowledged algae expert with interest in plant reproductive processes. In 1858 Mendel had nominated Nave as a new member of the scientific section of the Agricultural Society. A scientific connection between Mendel and Nave has been conjectured previously; however, evidence was lacking so far. After his early death in 1864, Nave’s scientific library was acquired by the Natural Science Society. It contained books about the latest insights on plant fertilization, and since Mendel’s 1866-paper contains a lengthy footnote about this topic, Mendel and Nave likely discussed this area of Mendel’s research. This may also have been the case during their journey to Paris and London because it was in 1862 that Mendel conducted the final crossing experiments to test his hypothesis about the composition and the random union of pollen and egg cells

    A previously unknown journey by Gregor Mendel to Leipzig in September 1865 and his likely participation in the Botanical Congress in Erfurt

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    A hitherto unknown visit by Gregor Mendel to Leipzig, Germany, in September 1865 has been discovered in digitized German newspapers. This trip took place after his two lectures on his pea experiments but before the publication of his later famous article on plant hybrids. The probable purpose of this trip was to visit the Second Congress of German Horticulturists and Botanists and Gardening Enthusiasts, combined with the German Exhibition of Agricultural Products in nearby Erfurt. Crosses between plant species and varieties were among the main topics of the Congress. Mendel's participation cannot be proven beyond doubt, but other participants in the Congress arrived in Leipzig at the same time as Mendel and even stayed in the same hotel. In addition, the uniqueness of the Exhibition and the topics covered at the Congress make it very likely that this was the purpose of his trip. We propose that Mendel's participation in the Congress could explain the early publication of an abridged version of Mendel's article in Bamberg and that the Erfurter plant breeder and seed merchant Ernst Benary was acquainted with Mendel's pea experiments

    Challenging Perceptions of Disability through Performance Poetry Methods: The "Seen but Seldom Heard" Project.

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    This paper considers performance poetry as a method to explore lived experiences of disability. We discuss how poetic inquiry used within a participatory arts-based research framework can enable young people to collectively question society’s attitudes and actions towards disability. Poetry will be considered as a means to develop a more accessible and effective arena in which young people with direct experience of disability can be empowered to develop new skills that enable them to tell their own stories. Discussion of how this can challenge audiences to critically reflect upon their own perceptions of disability will also be developed

    <em>NODULE ROOT</em> and <em>COCHLEATA</em> Maintain Nodule Development and Are Legume Orthologs of Arabidopsis <em>BLADE-ON-PETIOLE</em> Genes

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    During their symbiotic interaction with rhizobia, legume plants develop symbiosis-specific organs on their roots, called nodules, that house nitrogen-fixing bacteria. The molecular mechanisms governing the identity and maintenance of these organs are unknown. Using Medicago truncatula nodule root (noot) mutants and pea (Pisum sativum) cochleata (coch) mutants, which are characterized by the abnormal development of roots from the nodule, we identified the NOOT and COCH genes as being necessary for the robust maintenance of nodule identity throughout the nodule developmental program. NOOT and COCH are Arabidopsis thaliana BLADE-ON-PETIOLE orthologs, and we have shown that their functions in leaf and flower development are conserved in M. truncatula and pea. The identification of these two genes defines a clade in the BTB/POZ-ankyrin domain proteins that shares conserved functions in eudicot organ development and suggests that NOOT and COCH were recruited to repress root identity in the legume symbiotic organ

    Organization and molecular evolution of a disease-resistance gene cluster in coffee trees

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    <p>Abstract</p> <p>Background</p> <p>Most disease-resistance (R) genes in plants encode NBS-LRR proteins and belong to one of the largest and most variable gene families among plant genomes. However, the specific evolutionary routes of NBS-LRR encoding genes remain elusive. Recently in coffee tree (<it>Coffea arabica</it>), a region spanning the <it>S</it><sub><it>H</it></sub><it>3 </it>locus that confers resistance to coffee leaf rust, one of the most serious coffee diseases, was identified and characterized. Using comparative sequence analysis, the purpose of the present study was to gain insight into the genomic organization and evolution of the <it>S</it><sub><it>H</it></sub><it>3 </it>locus.</p> <p>Results</p> <p>Sequence analysis of the <it>S</it><sub><it>H</it></sub><it>3 </it>region in three coffee genomes, E<sup>a </sup>and C<sup>a </sup>subgenomes from the allotetraploid <it>C. arabica </it>and C<sup>c </sup>genome from the diploid <it>C. canephora</it>, revealed the presence of 5, 3 and 4 R genes in E<sup>a</sup>, C<sup>a</sup>, and C<sup>c </sup>genomes, respectively. All these R-gene sequences appeared to be members of a CC-NBS-LRR (CNL) gene family that was only found at the <it>S</it><sub><it>H</it></sub><it>3 </it>locus in <it>C. arabica</it>. Furthermore, while homologs were found in several dicot species, comparative genomic analysis failed to find any CNL R-gene in the orthologous regions of other eudicot species. The orthology relationship among the <it>S</it><sub><it>H</it></sub><it>3</it>-CNL copies in the three analyzed genomes was determined and the duplication/deletion events that shaped the <it>S</it><sub><it>H</it></sub><it>3 </it>locus were traced back. Gene conversion events were detected between paralogs in all three genomes and also between the two sub-genomes of <it>C. arabica</it>. Significant positive selection was detected in the solvent-exposed residues of the <it>S</it><sub><it>H</it></sub><it>3</it>-CNL copies.</p> <p>Conclusion</p> <p>The ancestral <it>S</it><sub><it>H</it></sub><it>3</it>-CNL copy was inserted in the <it>S</it><sub><it>H</it></sub><it>3 </it>locus after the divergence between Solanales and Rubiales lineages. Moreover, the origin of most of the <it>S</it><sub><it>H</it></sub><it>3</it>-CNL copies predates the divergence between <it>Coffea </it>species. The <it>S</it><sub><it>H</it></sub><it>3</it>-CNL family appeared to evolve following the birth-and-death model, since duplications and deletions were inferred in the evolution of the <it>S</it><sub><it>H</it></sub><it>3 </it>locus. Gene conversion between paralog members, inter-subgenome sequence exchanges and positive selection appear to be the major forces acting on the evolution of <it>S</it><sub><it>H</it></sub><it>3</it>-CNL in coffee trees.</p

    Use of anticoagulants and antiplatelet agents in stable outpatients with coronary artery disease and atrial fibrillation. International CLARIFY registry

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