159 research outputs found

    Bill Dawson, Danny Lowe, and Ellis Melton in a Joint Junior Recital

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    This is the program for the joint junior brass recital of trumpet player Bill Dawson, bassoonist Danny Lowe, and trombonist Ellis Melton. Kay Miller and Robert Braswell accompanied the performance. The recital took place on March 16, 1965, in Mitchell Auditorium

    Institutional responses to electronic procurement in the public sector

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    Purpose: The primary aim of the research presented in this paper is to address the gap in the literature with regard to the factors that affect the uptake and application of e-procurement within the public sector. Design/methodology/approach: This analysis was achieved through five in-depth case studies – based upon extensive interviews, observation and documentation reviews - conducted within central and local government organisations. Findings: The study shows that despite being very different in terms of their form and function, each of our five case study organisations had achieved similar levels of progress in terms of their adoption of e-procurement technologies. In short every organisation had already adopted BACS, all five were also actively planning to implement: e-tendering; e-award; e-contract and e-catalogue systems, but none had any intention of adopting e-marketplaces or e-auctions. Research limitation/implications: The results of this study will help individual organisations to better understand their current situations and the barriers that will need to be overcome before they can significantly expand their adoption of e-procurement technologies. Originality/value: In addition to presenting one of the first detailed studies of the adoption of e-procurement technologies, this study also breaks new ground through its use of the lens of "Institutional theory" to help interpret the findings

    Neutralino dark matter annihilation to monoenergetic gamma rays as a signal of low mass superstrings

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    We consider extensions of the standard model based on open strings ending on D-branes, in which gauge bosons and their associated gauginos exist as strings attached to stacks of D-branes, and chiral matter exists as strings stretching between intersecting D-branes. Under the assumptions that the fundamental string scale is in the TeV range and the theory is weakly coupled, we study models of supersymmetry for which signals of annihilating neutralino dark matter are observable. In particular, we construct a model with a supersymmetric R-symmetry violating (but R-parity conserving) effective Lagrangian that allows for the s-wave annihilation of neutralinos, once gauginos acquire mass through an unspecified mechanism. The model yields bino-like neutralinos (with the measured relic abundance) that annihilate to a gamma-gamma final state with a substantial branching fraction (~ 10%) that is orders of magnitude larger than in the minimal supersymmetric standard model. A very bright gamma-ray spectral line could be observed by gamma-ray telescopes.Comment: 9 revtex pages, 2 figure

    Spatial Variability of Shortwave Irradiance for Snowmelt in Forests

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    The spatial variation of melt energy can influence snow cover depletion rates and in turn be influenced by the spatial variability of shortwave irradiance to snow. The spatial variability of shortwave irradiance during melt under uniform and discontinuous evergreen canopies at a U. S. Rocky Mountains site was measured, analyzed, and then compared to observations from mountain and boreal forests in Canada. All observations used arrays of pyranometers randomly spaced under evergreen canopies of varying structure and latitude. The spatial variability of irradiance for both overcast and clear conditions declined dramatically, as the sample averaging interval increased from minutes to 1 day. At daily averaging intervals, there was little influence of cloudiness on the variability of subcanopy irradiance; instead, it was dominated by stand structure. The spatial variability of irradiance on daily intervals was higher for the discontinuous canopies, but it did not scale reliably with canopy sky view. The spatial variation in irradiance resulted in a coefficient of variation of melt energy of 0.23 for the set of U. S. and Canadian stands. This variability in melt energy smoothed the snow-covered area depletion curve in a distributed melt simulation, thereby lengthening the duration of melt by 20%. This is consistent with observed natural snow cover depletion curves and shows that variations in melt energy and snow accumulation can influence snow-covered area depletion under forest canopies

    Hexabundles: imaging fiber arrays for low-light astronomical applications

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    We demonstrate a novel imaging fiber bundle ("hexabundle") that is suitable for low-light applications in astronomy. The most successful survey instruments at optical-infrared wavelengths use hundreds to thousands of multimode fibers fed to one or more spectrographs. Since most celestial sources are spatially extended on the celestial sphere, a hexabundle provides spectroscopic information at many distinct locations across the source. We discuss two varieties of hexabundles: (i) lightly fused, closely packed, circular cores; (ii) heavily fused non-circular cores with higher fill fractions. In both cases, we find the important result that the cladding can be reduced to ~2 μm over the short fuse length, well below the conventional ~10λ thickness employed more generally, with a consequent gain in fill factor. Over the coming decade, it is to be expected that fiber-based instruments will be upgraded with hexabundles in order to increase the spatial multiplex capability by two or more orders of magnitude

    Implementation of the Power to Prevent Diabetes Prevention Educational Curriculum Into Rural African American Communities: A Feasibility Study

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    The purpose of this study was to describe the feasibility of using a Community Based Participatory Research (CBPR) approach to implement the Power to Prevent (P2P) diabetes prevention education curriculum in rural African American (AA) settings

    A gauge-mediated supersymmetry breaking model with an extra singlet Higgs field

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    We study in some detail the next-to-minimal supersymmetric standard model with gauge mediation of supersymmetry breaking. We find that it is feasible to spontaneously generate values of the Higgs mass parameters μ\mu and BμB_\mu consistent with radiative electroweak symmetry breaking. The model has a phenomenologically viable particle spectrum. Messenger sneutrinos with mass in the range 6 to 25 TeV can serve as cold dark matter. It is also possible to evade the cosmological domain wall problem in this scenario.Comment: revised version to appear in PR

    Examining leptogenesis with lepton flavor violation and the dark matter abundance

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    Within a supersymmetric (SUSY) type-I seesaw framework with flavor-blind universal boundary conditions, we study the consequences of requiring that the observed baryon asymmetry of the Universe be explained by either thermal or non-thermal leptogenesis. In the former case, we find that the parameter space is very constrained. In the bulk and stop-coannihilation regions of mSUGRA parameter space (that are consistent with the measured dark matter abundance), lepton flavor-violating (LFV) processes are accessible at MEG and future experiments. However, the very high reheat temperature of the Universe needed after inflation (of about 10^{12} GeV) leads to a severe gravitino problem, which disfavors either thermal leptogenesis or neutralino dark matter. Non-thermal leptogenesis in the preheating phase from SUSY flat directions relaxes the gravitino problem by lowering the required reheat temperature. The baryon asymmetry can then be explained while preserving neutralino dark matter, and for the bulk or stop-coannihilation regions LFV processes should be observed in current or future experiments.Comment: 20 pages, 5 figures, 1 tabl

    Widespread exon skipping triggers degradation by nuclear RNA surveillance in fission yeast

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    Exon skipping is considered a principal mechanism by which eukaryotic cells expand their transcriptome and proteome repertoires, creating different splice variants with distinct cellular functions. Here we analyze RNA-seq data from 116 transcriptomes in fission yeast (Schizosaccharomyces pombe), covering multiple physiological conditions as well as transcriptional and RNA processing mutants. We applied brute-force algorithms to detect all possible exon-skipping events, which were widespread but rare compared to normal splicing events. Exon-skipping events increased in cells deficient for the nuclear exosome or the 5'-3' exonuclease Dhp1, and also at late stages of meiotic differentiation when nuclear-exosome transcripts decreased. The pervasive exon-skipping transcripts were stochastic, did not increase in specific physiological conditions, and were mostly present at less than one copy per cell, even in the absence of nuclear RNA surveillance and during late meiosis. These exon-skipping transcripts are therefore unlikely to be functional and may reflect splicing errors that are actively removed by nuclear RNA surveillance. The average splicing rate by exon skipping was ∼ 0.24% in wild type and ∼ 1.75% in nuclear exonuclease mutants. We also detected approximately 250 circular RNAs derived from single or multiple exons. These circular RNAs were rare and stochastic, although a few became stabilized during quiescence and in splicing mutants. Using an exhaustive search algorithm, we also uncovered thousands of previously unknown splice sites, indicating pervasive splicing; yet most of these splicing variants were cryptic and increased in nuclear degradation mutants. This study highlights widespread but low frequency alternative or aberrant splicing events that are targeted by nuclear RNA surveillance

    Multidisciplinary consensus guideline for the diagnosis and management of spontaneous intracranial hypotension

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    BACKGROUND: We aimed to create a multidisciplinary consensus clinical guideline for best practice in the diagnosis, investigation and management of spontaneous intracranial hypotension (SIH) due to cerebrospinal fluid leak based on current evidence and consensus from a multidisciplinary specialist interest group (SIG). METHODS: A 29-member SIG was established, with members from neurology, neuroradiology, anaesthetics, neurosurgery and patient representatives. The scope and purpose of the guideline were agreed by the SIG by consensus. The SIG then developed guideline statements for a series of question topics using a modified Delphi process. This process was supported by a systematic literature review, surveys of patients and healthcare professionals and review by several international experts on SIH. RESULTS: SIH and its differential diagnoses should be considered in any patient presenting with orthostatic headache. First-line imaging should be MRI of the brain with contrast and the whole spine. First-line treatment is non-targeted epidural blood patch (EBP), which should be performed as early as possible. We provide criteria for performing myelography depending on the spine MRI result and response to EBP, and we outline principles of treatments. Recommendations for conservative management, symptomatic treatment of headache and management of complications of SIH are also provided. CONCLUSIONS: This multidisciplinary consensus clinical guideline has the potential to increase awareness of SIH among healthcare professionals, produce greater consistency in care, improve diagnostic accuracy, promote effective investigations and treatments and reduce disability attributable to SIH
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