493 research outputs found

    A Development Plan for the Museums at Union Station in Ogden, Utah

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    This study is concerned with a comparison of the contemporary to the traditional museum. It analyzes the evolution of roles for museums and considers the changing nature of their support. Using a broad survey of literature related to museums, considerable personal experience and extensive visits and interviews with other museums, it develops the thesis that today\u27s successful museum depends upon a diverse resource and program base. An application of this hypothesis is then made to the museums at Union Station in Ogden, Utah. The product of the study is intended to be a working plan for museum development at Union Station for the period of 1980 to 1985 and it is planned also as a prototype for other museums with similar objectives. Union Station is the rail passenger depot in Ogden, known as Junction City for its role in the construction of the nation\u27s first transcontinental railroad. The building is listed on the National Register of Historic Sites and is within the 25th Street National Historic District. It is an active passenger station for AMTRAK; an office for the Union Pacific and Southern Pacific Railroads; an office of the Ogden Union Railway and Depot Company and also the regional tourist promotion agency--Golden Spike Empire, Incorporated. The nucleus of the Union Station project is the museum complex, including the Railroad Museum, the Browning Firearms Museum, and the Kimball-Browning Vintage Car Museum. These functions occupy approximately one-third of the total space at Union Station and must be supported by revenue from other activities as well as from the admissions and sales they themselves generate. The Union Station objectives of providing museums; economic stability to an historic but debilitated area; a civic and cultural center for the community; an attraction for tourists, and a meeting and convention center are examined in the context of economic self-sufficiency and historic preservation. The components of a museum program are evaluated, including acquisitions; collections and exhibits; interpretations; registration methods; conservation, and archives and research. Museum management is considered for both personnel and physical planning. Financial development addresses policies and plans for admissions; grants; contributions; a museum shop; a membership program, and fund-raising events. Public relations and promotion and an outreach program conclude the topics of the study. An appendix includes several useful sections for museum professionals, such as a syllabus for staff training; a glossary; maintenance manual suggestions; a docent orientation course outline, and a five year financial development plan

    Observations and properties of candidate high frequency GPS radio sources in the AT20G survey

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    We used the Australia Telescope Compact Array (ATCA) to obtain 40 GHz and 95 GHz observations of a number of sources that were selected from the Australia Telescope Compact Array 20 GHz (AT20G) survey . The aim of the observations was to improve the spectral coverage for sources with spectral peaks near 20 GHz or inverted (rising) radio spectra between 8.6 GHz and 20 GHz. We present the radio observations of a sample of 21 such sources along with optical spectra taken from the ANU Siding Spring Observatory 2.3m telescope and the ESO-New Technology Telescope (NTT). We find that as a group the sources show the same level of variability as typical GPS sources, and that of the 21 candidate GPS sources roughly 60% appear to be genuinely young radio galaxies. Three of the 21 sources studied show evidence of being restarted radio galaxies. If these numbers are indicative of the larger population of AT20G radio sources then as many as 400 genuine GPS sources could be contained within the AT20G with up to 25% of them being restarted radio galaxies.Comment: 21 pages, 24 figures, Table 1 truncated at 11 column

    The Epstein-Barr Virus Polymerase Accessory Factor BMRF1 Adopts a Ring-shaped Structure as Visualized by Electron Microscopy

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    Epstein-Barr virus (EBV) encodes a set of core replication factors used during lytic infection in human cells that parallels the factors used in many other systems. These include a DNA polymerase and its accessory factor, a helicase/primase, and a single strand binding protein. The EBV polymerase accessory factor has been identified as the product of the BMRF1 gene and has been shown by functional assays to increase the activity and processivity of the polymerase. Unlike other members of this class of factors, BMRF1 is also a transcription factor regulating certain EBV genes. Although several polymerase accessory factors, including eukaryotic proliferating cell nuclear antigen, Escherichia coli beta protein, and T4 gene 45 protein have been shown to form oligomeric rings termed sliding clamps, nothing is known about the oligomeric state of BMRF1 or whether it forms a ring. In this work, BMRF1 was purified directly from human cells infected with an adenovirus vector expressing the BMRF1 gene product. The protein was purified to near homogeneity, and examination by negative staining electron microscopy revealed large, flat, ring-shaped molecules with a diameter of 15.5 +/- 0.8 nm and a distinct 5.3-nm diameter hole in the center. The size of these rings is consistent with an oligomer of 6 monomers, nearly twice as large as the trimeric proliferating cell nuclear antigen ring. Unlike the herpes simplex virus UL42 homologue, BMRF1 was found to self-associate in solution. These findings extend the theme of polymerase accessory factors adopting ring-shaped structures and provide an example in which the ring is significantly larger than any previously described sliding clamp

    Metagenomic analysis of DNA viruses with targeted sequence capture of canine lobular orbital adenomas and normal conjunctiva

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    Our study aims are: (1) to evaluate phenotypically normal canine conjunctival and orbital tissue and tissue from canine lobular orbital adenomas (CLOAs) for the presence of viral genomic material and (2) phylogenetically classify detected DNA viruses to determine if a DNA virus is associated with CLOAs. A total of 31 formalin fixed paraffin embedded CLOA tissue samples, 4 papillomas or sarcoid, and 10 fresh clinically normal conjunctival tissues were included in this study. Genomic DNA was isolated from all samples and sequencing libraries were prepared. The libraries were molecularly indexed and pooled and viral DNA was enriched via targeted sequence capture utilizing ViroCap. The libraries were sequenced on the Illumina HiSeq platform and compared to known viral DNA reference genomes to identify viral DNA. Carnivore parvovirus was identified in 6.4% and 20% of CLOA tissue and normal conjunctival samples, respectively. This study showed that conjunctival tissue from healthy dogs and CLOAs uncommonly harbor DNA viruses, and no DNA virus was associated with these tumors. Further studies are needed to evaluate the etiologic cause of CLOAs

    The Ursinus Weekly, February 25, 1952

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    Frats begin rushing for new pledges • Sororities to start rushing March 3 • Any student urged to try out for Spring production • Freshman dance to be celestial • Group plays postponed • History of Anglo-Egyptian relations traced by speaker • Jeanne Careless chosen queen • Campaign against cutting campus begun by WSGA • Newman Club hears psychology talk • Blood donations sought again here • Piano-violin concert received favorably by Ursinus audience • Economics of marriage discussed at seminar • Fastnacht ball planned by clubs • Editorials: Needed - codified law; Is Korean War necessary? • Student Union ideas given • Five initiated into Rosicrucians society • Canterbury Club holds supper • Engagement • Forum tickets available • Former German student comes to Ursinus this semester • Dr. C. L. Chandler receives honor • Mr. Dolman gives Twain selections at English readings • Guest lecturer tells of history of aeronautics • Ursinus students glimpse preview of Mardi Gras scene • Grizzlies trounce Textile to break losing streak • Badminton squad defeats Rosemont in opening game • Beaver College basketball team deadlocks Snell\u27s Belles at 25 • Girls\u27 intramural loop is underway • Beaver hands Ursinus Mermaids first loss • Penn JVs overpower girls\u27 badminton team • Chess Club wins • Grizzlies defeated by Bucknell team • Ursinus quintet stifles Ford rally to win 71-51 • League I champs may be crowned in tonight\u27s play • Doctor speaks on psychiatry to studentshttps://digitalcommons.ursinus.edu/weekly/1535/thumbnail.jp

    Visible and Invisible Trends in Black Men's Health: Pitfalls and Promises for Addressing Racial, Ethnic, and Gender Inequities in Health

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    Over the past two decades, there has been growing interest in improving black men's health and the health disparities affecting them. Yet, the health of black men consistently ranks lowest across nearly all groups in the United States. Evidence on the health and social causes of morbidity and mortality among black men has been narrowly concentrated on public health problems (e.g., violence, prostate cancer, and HIV/AIDS) and determinants of health (e.g., education and male gender socialization). This limited focus omits age-specific leading causes of death and other social determinants of health, such as discrimination, segregation, access to health care, employment, and income. This review discusses the leading causes of death for black men and the associated risk factors, as well as identifies gaps in the literature and presents a racialized and gendered framework to guide efforts to address the persistent inequities in health affecting black men

    Follow-up observations at 16 and 33 GHz of extragalactic sources from WMAP 3-year data: I - Spectral properties

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    We present follow-up observations of 97 point sources from the Wilkinson Microwave Anisotropy Probe (WMAP) 3-year data, contained within the New Extragalactic WMAP Point Source (NEWPS) catalogue between declinations of -4 and +60 degrees; the sources form a flux-density-limited sample complete to 1.1 Jy (approximately 5 sigma) at 33 GHz. Our observations were made at 16 GHz using the Arcminute Microkelvin Imager (AMI) and at 33 GHz with the Very Small Array (VSA). 94 of the sources have reliable, simultaneous -- typically a few minutes apart -- observations with both telescopes. The spectra between 13.9 and 33.75 GHz are very different from those of bright sources at low frequency: 44 per cent have rising spectra (alpha < 0.0), where flux density is proportional to frequency^-alpha, and 93 per cent have spectra with alpha < 0.5; the median spectral index is 0.04. For the brighter sources, the agreement between VSA and WMAP 33-GHz flux densities averaged over sources is very good. However, for the fainter sources, the VSA tends to measure lower values for the flux densities than WMAP. We suggest that the main cause of this effect is Eddington bias arising from variability.Comment: 12 pages, 13 figures, submitted to MNRA
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