Convergencia económica en los departamentos de Mendoza

This article looks at the evidence of economic convergence across Mendoza departments from 1996 to 2012. The evolution of regional inequality is analyzed through disparity and dispersion indices and growth gaps. No evidence of territorial convergence has been found. The estimated β coefficient is positive and statistically not significant; Williamson’s coefficient, σ convergence and growth gaps show a slight inequality increase, particularly during booms. Similarly, no evidence of a positive relation between agricultural specialization and growth has been found. In fact, our results suggest that the agricultural territories, i. e. , the comparatively less-developed ones, do not exhibit an improvement in their relative position, despite the favorable international context.En este trabajo se analiza la convergencia económica de los departamentos de Mendoza durante el período 1996 a 2012. Se examina la evolución de las desigualdades territoriales mediante indicadores de disparidad, dispersión y brechas de crecimiento. No se encuentran evidencias de un proceso de convergencia territorial. El coeficiente β estimado resulta positivo y estadísticamente no significativo; el Coeficiente de Williamson, σ-convergencia y brechas de crecimiento revelan un leve aumento de la desigualdad, especialmente durante períodos de auge. Tampoco se encontró evidencia de relación positiva entre crecimiento y especialización agropecuaria. La inserción internacional del sector agroindustrial no contribuyó a mejorar significativamente la situación de los territorios fuertemente agropecuarios, los de menor desarrollo relativo provincial

New & Noteworthy, February 2018

Contents include: Q & A: Elizabeth Bojsza and Lydia Franco-Hodges; VP Publications Kristin Leahey LMDA Review - Updates; Regional Updates.https://soundideas.pugetsound.edu/lmdanewsletter/1017/thumbnail.jp

Heterologous matrix metalloproteinase gene promoter activity allows In Vivo real-time imaging of Bleomycin-induced Lung fibrosis in transiently transgenized mice

Idiopathic pulmonary fibrosis is a very common interstitial lung disease derived from chronic inflammatory insults, characterized by massive scar tissue deposition that causes the progressive loss of lung function and subsequent death for respiratory failure.Bleomycin is used as the standard agent to induce experimental pulmonary fibrosis in animal models for the study of its pathogenesis. However, to visualize the establishment of lung fibrosis after treatment, the animal sacrifice is necessary. Thus, the aim of this study was to avoid this limitation by using an innovative approach based on a double bleomycin treatment protocol, along with the in vivo images analysis of bleomycintreated mice. A reporter gene construct, containing the luciferase open reading frame under the matrix metalloproteinase-1 promoter control region, was tested on doublebleomycin-treated mice to investigate, in real time, the correlation between bleomycin treatment, inflammation, tissue remodeling and fibrosis. Bioluminescence emitted by the lungs of bleomycin-treated mice, corroborated by fluorescent molecular tomography, successfully allowed real time monitoring of fibrosis establishment. The reporter gene technology experienced in this work could represent an advanced functional approach for real time non-invasive assessment of disease evolution during therapy, in a reliable and translational living animal model.Fil: Stellari, Fabio Franco. Chiese Farmaceutici; ItaliaFil: Ruscitti, Francesca. Chiese Farmaceutici; ItaliaFil: Pompilio, Daniela. Chiese Farmaceutici; ItaliaFil: Ravanetti, Francesca. Università di Parma. Dipartimento di Scienze Medico Veterinarie; ItaliaFil: Tebaldi, Giulia. Università di Parma. Dipartimento di Scienze Medico Veterinarie; ItaliaFil: Macchi, Francesca. Università di Parma. Dipartimento di Scienze Medico Veterinarie; ItaliaFil: Verna, Andrea Elizabeth. Instituto Nacional de Tecnología Agropecuaria. Centro Regional Buenos Aires Sur. Estación Experimental Agropecuaria Balcarce; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Chiese Farmaceutici; ItaliaFil: Villetti, Gino. Chiese Farmaceutici; ItaliaFil: Donofrio, Gaetano. Università di Parma. Dipartimento di Scienze Medico Veterinarie ; Itali

A global information system for the conservation and sustainable use of Plant Genetic Resources for Food and Agriculture (PGRFA)

Poster presented at 2008 Annual Meeting of TD WG-Biodiversity Information Standards. Fremantle ( Australia), 19-24 Oct 200

Residues located inside the Escherichia coli FepE protein oligomer are essential for lipopolysaccharide O-antigen modal chain length regulation

The Escherichia coli O157 : H7 FepE protein regulates lipopolysaccharide (LPS) O-antigen (Oag) chain length to confer a very long modal chain length of >80 Oag repeat units (RUs). The mechanism by which FepE regulates Oag modal chain length and the regions within it that are important for its function remain unclear. Studies on the structure of FepE show that the protein oligomerizes. However, the exact size of the oligomer is in dispute, further hampering our understanding of its mechanism. Guided by information previously obtained for regions known to be important for Oag modal chain length determination in the homologous Shigella flexneri WzzBSF protein, a set of FepE mutant constructs with single amino acid substitutions was created. Analysis of the resulting LPS conferred by these mutant His6-FepE proteins showed that amino acid substitutions of leucine 168 (L168) and aspartic acid 268 (D268) resulted in LPS with consistently shortened Oag chain lengths of <80 Oag RUs. Substitution of FepE’s transmembrane cysteine residues did not affect function. Chemical cross-linking experiments on mutant FepE proteins showed no consistent correlation between oligomer size and functional activity, and MS analysis of FepE oligomers indicated that the in vivo size of FepE is consistent with a maximum size of a hexamer. Our findings suggest that different FepE residues, mainly located within the internal cavity of the oligomer, contribute to Oag modal chain length determination but not the oligomeric state of the protein.Elizabeth Ngoc Hoa Tran and Renato Moron