Risky Behaviours Among Young People Living with HIV Attending Care and Treatment Clinics in Dar Es Salaam, Tanzania: Implications for Prevention with a Positive Approach.

Introduction: Prevention with a positive approach has been advocated as one of the main strategies to reduce new instances of HIV infection. Risky sexual behaviours among people living with HIV/AIDS are the cornerstone for this approach. Understanding the extent to which infected individuals practice risky behaviours is fundamental in designing appropriate population-specific interventions. With the HIV infection transmission rates remaining high among young people in sub-Saharan Africa, continued prevention among them remains a priority. This study therefore seeks to describe the magnitude and determinants of risky sexual behaviours among young people living with HIV. Methods: A cross-sectional study was conducted between June and July 2010 in selected Care and Treatment Clinics (CTCs) in Dar Es Salaam, Tanzania. A total of 282 HIV-positive patients aged 15-24 were interviewed about their sexual behaviours using a questionnaire. Results: Prevalence of unprotected sex was 40.0% among young males and 37.5% among young females (p<0.001). Multiple sexual partnerships were reported by 10.6% of males and 15.9% of females (p<0.005). More than 50% of the participants did not know about the HIV status of their sexual partners. A large proportion of participants had minimal knowledge of transmission (46.7% males vs. 60.4% females) and prevention (65.3% males vs. 73.4% females) of sexually transmitted infections (STIs). Independent predictors of condom use included non-use of alcohol [adjusted odds ratio (AOR), 0.40 95% confidence interval (CI); 0.17-0.84] and younger age (15-19 years) (AOR, 2.76, 95% CI: 1.05-7.27). Being on antiretroviral therapy (AOR, 0.38, 95% CI: 0.17-0.85) and not knowing partners' HIV sero-status (AOR, 2.62, 95% CI: 1.14-5.10) predicted the practice of multiple sexual partnership. Conclusions: Unprotected sex and multiple sexual partnerships were prevalent among young people living with HIV. Less knowledge on STI and lack of HIV disclosure increased the vulnerability and risk for HIV transmission among young people. Specific intervention measures addressing alcohol consumption, risky sexual behaviours, and STI transmission and prevention knowledge should be integrated in the routine HIV/AIDS care and treatment offered to this age group

Food Insecurity is Associated with Food Consumption Patterns and Anthropometric Measures but not Serum Micronutrient Levels in Adults in Rural Tanzania.

The purpose of the present paper is to assess the relationship between food insecurity and food consumption patterns, anthropometric measures and serum micronutrient levels in rural Kilimanjaro, Tanzania. A population-based cross-sectional study was carried out between March and May of 2005. Rural Kilimanjaro, Tanzania. Analysis was restricted to 1014 adults aged 15-44 years with children and complete data. A large majority of the participants (91 %) reported some kind of food insecurity. Food insecurity was significantly associated with age, marital status and occupation. Participants reporting food insecurity were significantly less likely to frequently consume animal products, fruits and vegetables compared with participants categorized as food secure. Women categorized as experiencing individual food insecurity had a larger waist circumference than food-secure women (P = 0.026) while the mean BMI of women appeared to decline if they had a child who was food insecure (P = 0.038). There were no observed differences in serum micronutrient levels by food insecurity status. Food insecurity is highly prevalent and associated with food consumption patterns, waist circumference and BMI of women in rural Tanzania. Further studies should apply self-report measures in assessing food insecurity to larger and more diversified populations

Assessing the Potential Risks of Digital Therapeutics (DTX): The DTX Risk Assessment Canvas

Motivation: Digital therapeutics (DTX), i.e., health interventions that are provided through digital means, are increasingly available for use; in some countries, physicians can even prescribe selected DTX following a reimbursement by health insurances. This results in an increasing need for methodologies to consider and monitor DTX’s negative consequences, their risks to patient safety, and possible adverse events. However, it is completely unknown which aspects should be subject to surveillance given the missing experiences with the tools and their negative impacts. Objective: Our aim is to develop a tool—the DTX Risk Assessment Canvas—that enables researchers, developers, and practitioners to reflect on the negative consequences of DTX in a participatory process. Method: Taking the well-established business model canvas as a starting point, we identified relevant aspects to be considered in a risk assessment of a DTX. The aspects or building blocks of the canvas were constructed in a two-way process: first, we defined the aspects relevant for discussing and reflecting on how a DTX might bring negative consequences and risks for its users by considering ISO/TS 82304-2, the scientific literature, and by reviewing existing DTX and their listed adverse effects. The resulting aspects were grouped into thematic blocks and the canvas was created. Second, six experts in health informatics and mental health provided feedback and tested the understandability of the initial canvas by individually applying it to a DTX of their choice. Based on their feedback, the canvas was modified. Results: The DTX Risk Assessment Canvas is organized into 15 thematic blocks which are in turn grouped into three thematic groups considering the DTX itself, the users of the DTX, and the effects of the DTX. For each thematic block, questions have been formulated to guide the user of the canvas in reflecting on the single aspects. Conclusions: The DTX Risk Assessment Canvas is a tool to reflect the negative consequences and risks of a DTX by discussing different thematic blocks that together constitute a comprehensive interpretation of a DTX regarding possible risks. Applied during the DTX design and development phase, it can help in implementing countermeasures for mitigation or means for their monitoring

Production of hot Jupiter candidates from high-eccentricity mechanisms for different initial planetary mass configurations

Hot Jupiters (HJs) are giant planets with orbital periods of the order of a few days with semimajor axis within ∼0.1 au. Several theories have been invoked in order to explain the origin of this type of planets, one of them being the high-eccentricity migration. This migration can occur through different high-eccentricity mechanisms. Our investigation focused on six different kinds of high-eccentricity mechanisms, namely, direct dispersion, coplanar, Kozai-Lidov, secular chaos, E1 and E2 mechanisms. We investigated the efficiency of these mechanisms for the production of HJ candidates in multiplanet systems initially tightly-packed in the semimajor axis, considering a large set of numerical simulations of the exact equations of motion in the context of the N-body problem. In particular, we analyzed the sensitivity of our results to the initial number of planets, the initial semimajor axis of the innermost planetary orbit, the initial configuration of planetary masses, and to the inclusion of general relativity (GR) effects. We found that the E1 mechanism is the most efficient in producing HJ candidates both in simulations with and without the contribution of GR, followed by the Kozai-Lidov and E2 mechanisms. Our results also revealed that, except for the initial equal planetary mass configuration, the E1 mechanism was notably efficient in the other initial planetary mass configurations considered in this work. Finally, we investigated the production of HJ candidates with prograde, retrograde, and alternating orbits. According to our statistical analysis, the Kozai-Lidov mechanism has the highest probability of significantly exciting the orbital inclinations of the HJ candidates.Fil: Garzón, H.. Universidade Federal do Rio de Janeiro; BrasilFil: Rodríguez, Adrián. Universidade Federal do Rio de Janeiro; BrasilFil: de Elia, Gonzalo Carlos. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Astrofísica La Plata. Universidad Nacional de La Plata. Facultad de Ciencias Astronómicas y Geofísicas. Instituto de Astrofísica La Plata; Argentin

Studi Penggunaan Balok Lintel Pada Bangunan Gedung Infilled Frame 2 Lantai Menggunakan SAP2000

The two stories building construction or which is commonly called the two stories building these days is very popular in Indonesia. The type of multistories building technology that develop in the world of construction is very diverse, this development is can not be separated from the anticipation of the various of loading conditions. Based on that facts, the research of the use of lintel beams in 2 stories infilled frame buildings is conducted. The analysis can be done by using SAP2000 software. The structure model analyzed by comparing the structure responses between the building that use the lintel beams system and the other one is the building that don’t use that system, where as the idealized loading is same. The result of the analysis obtained by using the lintel beams system the value of maximum x and y axis base shear respectively are 344,088 KN and 363,001 KN, the maximum column moment is occurred in column 84 with the value is 99,58 kNm, and the maximum x axis lateral drift is occurred in joint 128 with the value is 0.000401 m, while the y axis is occurred in joint 105, 128 with the value is 0,000533 m. The analysis result that obtained for the building that don’t use the lintel beam system, the x and y axis maximum base shear value respectively is 336,425 KN and 354,539 KN, the maximum column moment occurs in column 84 is 98,98 kNm, and the x axis maximum drift lateral occurs in joint 128 with value is 0,000406, while the y axis maximum lateral drift occurs in joint 105, 128 with value is 0,000532. So we obtained the percentage comparison on base shear value between 2 stories infilled frame building that use lintel beams system and the building that doesn’t use the lintel beams system for x axis is 1,45% and y axis is 1,13% , and for the percentage comparison on maximum column moment value is 0,30% , while the percentage comparison on drift lateral value for x axis is 0,62% and y axis is 0,09

Profound inhibition of chronic itch induced by stimulation of thin cutaneous nerve fibres.

Background Despite the fact that severe itch is common in many dermatological diseases, the therapeutic arsenal against itching is limited. From neurophysiological experiments, using a new technique termed cutaneous field stimulation, it is known that acute itch can be effectively relieved by stimulation of cutaneous nociceptors. Methods We tested the effects of cutaneous field stimulation (25 min, 16 electrodes, 4 Hz per electrode, up to 0.8 mA) on chronic itch due to atopic dermatitis. Transcutaneous electrical nerve stimulation (100 Hz, up to 26 mA) was used for comparison. In 27 patients, itch was measured just prior to, during and at regular intervals up to 12 h after either type of treatment. Results Both treatments augmented the itch sensation during ongoing stimulation, presumably reflecting an altered sensory processing in the somatosensory pathways of chronic itch patients. However, after cessation of cutaneous field stimulation, but not transcutaneous electrical nerve stimulation, the itch sensation was significantly depressed for up to 7 h. The peak inhibitory effect (about 25% of control) was reached between 1 and 5 h poststimulation. Neither treatment had any significant effect on alloknesis, as measured before and 10 min after stimulation. Conclusion It is concluded that cutaneous field stimulation strongly depresses chronic itch, and is a potentially useful symptomatic treatment of itch

Magnitude and factors associated with overweight and obesity among adolescents in in semi-rural area of Babati District, Tanzania

 Background: Childhood and adolescent overweight and obesity have increased dramatically in recent years. We assessed the burden and factors associated with overweight and obesity among adolescents in a semi-rural district of Babati in Tanzania.Methods: A school-based descriptive cross-sectional survey was conducted among adolescents attending secondary schools. Anthropometric measurements were taken using standard procedures. A Food Frequency Questionnaire and the International Physical Activity Questionnaire were adapted to assess dietary and physical activity patterns, respectively.Results: A total of 619 students were included in the analysis. The mean age and body mass index of the respondents were 16.7±1.68 years and 19.9±3.16 kg/m², respectively. The overall prevalence of overweight and obesity was 9.2% with more girls being overweight and obese than boys (P&lt;0.0001). In the Generalized Estimating Equations (GEE) models, girls (Odds Ratio [OR] = 5.6; 95% Confidence Interval [CI]: 1.97, 15.72]); unhealthy diet (OR = 2.2; 95% CI: 1.32, 3.63); vigorous physical activity (OR = 2.2; 95%CI: 1.34, 3.56) and physical inactivity (OR = 1.7; 95%CI: 1.08, 2.79) were independent predictors of overweight or obesity.Conclusion: The prevalence of overweight and obesity was modest. Female sex, unhealthy diet and physical inactivity were significantly predictive. There is a need for interventions in obesity to have a broader target audience to include adolescents and residents of rural areas. Primary preventive interventions are needed.

The Preservation Of Dayak Suang Ensilat Language In Dusun Nanga Entibab Desa Nanga Dangkan Kecamatan Silat Hulu Kabupaten Kapuas Hulu

The preservation of the Dayak Suang Ensilat language in the Dusun Nanga Entibab on the family environment is still maintained, besides it is also seen in the language use in the workplace environment, shop / market environment, youth environment, parents' environment, church environment, traditional ceremonies and environment the village used the Dayak Suang Ensilat language when communicating. The researcher found that there were three factors that influenced the Dayak Suang Ensilat language, which were still maintained, namely, the factors of loyalty, pride and population

Variabilitas Suhu Permukaan Laut Dan Klorofil-a Kaitannya Dengan El Nino Southern Oscillation (Enso) Dan Indian Ocean Dipole (Iod) Pada Periode Upwelling 2010-2014 Di Lautan Hindia (Perairan Cilacap)

Perairan Cilacap merupakan salah satu perairan selatan Jawa yang memiliki variabilitas suhu permukaan laut (SPL) dan kesuburan perairan (konsentrasi klorofil-a) karena adanya pengaruh variabilitas iklim. Tujuan dari penelitian ini adalah mengkaji variabilitas SPL dan klorofil-a pada variasi tahunan (pengaruh angin monsun) dan antar tahunan (pengaruh ENSO dan IOD) di Perairan Cilacap. Data yang digunakan dalam penelitian ini meliputi data arus laut insitu, data SPL insitu, data SPL dan klorofil-a citra MODIS level 3, data angin dan arus BMKG Cilacap, data sea surface temperature (SST) di NINO3,4 dan data dipole mode index (DMI). Variabilitas nilai SPL dan klorofil-a secara tahunan menunjukkan bahwa pada bulan September selama tahun 2010-2014 didapatkan rerata SPL terendah yaitu sebesar 26,35 0C dan rerata konsentrasi klorofil-a tertinggi yaitu sebesar 1,16 mg/m3. Variabilitas nilai SPL dan klorofil-a antar tahunan menunjukkan rerata SPL terendah pada tahun 2011 yaitu sebesar 26,35 0C, sedangkan klorofil-a terdistribusi secara spasial mencapai titik koordinat 80 15' 0” LS (62 km dari garis pantai). Kondisi ini bertepatan dengan terjadinya La Nina sedang dan IOD positif (+) dengan durasi selama 5 bulan. Pada tahun 2012 didapatkan rerata konsentrasi klorofil-a tertinggi yaitu sebesar 0,974 mg/m3 namun hanya terdistribusi secara spasial pada titik koordinat 80 12' 9,3” LS (57 km dari garis pantai). Kondisi ini bertepatan dengan terjadinya fenomena El Nino lemah dan IOD(+) dengan durasi selama 3 bulan

Pengaruh Struktur Modal, Kebijakan Dividen, Ukuran Perusahaan,Kepemilikan Saham Manajerial Dan Profitabilitas Terhadap Nilai Perusahaan(Studi Pada Perusahaan Manufaktur Yang Terdaftar Di BEI Pada 2011-2013)

.The purpose of this study to analyse of capital structure, dividend policy, firm size, managerial stockownership and profitability of the value of manufacturing company in the Indonesia Stock Exchange.Samplingwas carried out with saturated sampling method that all 15 companies is used as a sample. Analysis of the datain this study using multiple regression. The results showed that the capital structure, dividend policy, the size ofthe company and profitability positive and significant effect of the company value, while the managerial stockownership does not effect the value of the company