H NMR Studies of Eukaryotic Cytochrome c

H NMR resonance assignments in the spectra of horse, tuna, Neurmpora crassa and Candida krusei cyto-chromes c are described. Assignments have been made using NMR double-resonance techniques in conjunction with electron-exchange experiments, spectral comparison of related proteins, and consideration of the X-ray structure of tuna cytochrome c. Resonances arising from 11 residues of horse cytochrome c have been assigned

Analysis of Compounded Pharmaceutical Products to Teach the Importance of Quality in an Applied Pharmaceutics Laboratory Course

Objective. To assess the effectiveness of a product-analysis laboratory exercise in teaching students the importance of quality in pharmaceutical compounding. Design. Second-year pharmacy students (N=77) participated in a pharmaceutical compounding laboratory exercise and subsequently analyzed their final product using ultraviolet (UV) spectrometry. Assessment. Reflection, survey instruments, and quiz questions were used to measure how well students understood the importance of quality in their compounded products. Product analysis showed that preparations compounded by students had an error range of 0.6% to 140%, with an average error of 23.7%. Students’ reflections cited common sources of error, including inaccurate weighing, contamination, and product loss during both the compounding procedure and preparation of the sample for analysis. Ninety percent of students agreed that the exercise improved their understanding of the importance of quality in compounded pharmaceutical products. Most students (85.7%) reported that this exercise inspired them to be more diligent in their preparation of compounded products in their future careers. Conclusion. Integrating an analytical assessment during a pharmaceutical compounding laboratory can enhance students’ understanding of quality of compounded pharmaceutical products. It can also provide students a chance to reflect on sources of error to improve their compounding technique in the future

Supply chain management practices and performance measures : case evidence from Malaysian automotive manufacturers / Eley Suzana Kasim

It has been noted that businesses seek to capitalize on their supply chain resources and capabilities as a way to achieve competitive advantage. From a competitive advantage viewpoint, supply chain management (SCM) has been widely advocated as a potential competitive management tool that contributes to firm performance, particularly in the automotive industry, the focus of this study. This industry is important because automotive firms are constantly responding to the changes following the environmental forces of globalization. A possible opportunity for advancement of SCM as a competitive management tool is the potential contribution of management accounting (MA) in utilizing SCM as a value creation tool. However, this is largely neglected in the literature. Furthermore, the shift towards value creation within SCM is consistent with recent developments in management accounting

Building health: an epidemiological study of "sick building syndrome" in the Whitehall II study

Objectives: Sick building syndrome (SBS) is described as a group of symptoms attributed to the physical environment of specific buildings. Isolating particular environmental features responsible for the symptoms has proved difficult. This study explores the role and significance of the physical and psychosocial work environment in explaining SBS. Methods: Cross sectional data on the physical environment of a selection of buildings were added to individual data from the Whitehall II study—an ongoing health survey of office based civil servants. A self-report questionnaire was used to capture 10 symptoms of the SBS and psychosocial work stress. In total, 4052 participants aged 42–62 years working in 44 buildings were included in this study. Results: No significant relation was found between most aspects of the physical work environment and symptom prevalence, adjusted for age, sex, and employment grade. Positive (non-significant) relations were found only with airborne bacteria, inhalable dust, dry bulb temperature, relative humidity, and having some control over the local physical environment. Greater effects were found with features of the psychosocial work environment including high job demands and low support. Only psychosocial work characteristics and control over the physical environment were independently associated with symptoms in the multivariate analysis. Conclusions: The physical environment of office buildings appears to be less important than features of the psychosocial work environment in explaining differences in the prevalence of symptoms

Evaluation of the health careers in the Bush Health Careers Workshops 1994 - 2002

[Summary]: Seventy people from rural backgrounds, who as secondary school students had attended a Year 10 Health Careers Workshop between 1995 and 1999, were interviewed by telephone in 2004 to determine what impact the workshop attendance had on their course and career choices. Approximately one quarter of the participants had also attended a Year 12 workshop. Results from two written questionnaires administered in 2002 and 2005 and from the telephone interviews showed that workshop attendance consolidated career interest in the health industry. At the end of 2004 over 90% of respondents were either employed in the health industry or studying to do so. Students who applied to attend a Year 10 workshop had expressed interest at that time of pursuing a health professional career such as nursing, medicine or physiotherapy. The workshops provided exposure to the variety of additional health related disciplines and some students used this information to modify their course and career plans within the industry. Even those who did not subsequently enrol in a health related course recognised the value of the workshop program. In fact without a single exception interviewees found the workshops to be extremely rewarding. The vast majority indicated that attendance had a major impact on their course and career decisions. A significant number of workshop participants have subsequently guided others in their course choice and career decisions. The majority of the participants who had left their rural communities to complete tertiary education will provide rural and regional health care as they have either returned and are working in rural or regional areas or intend doing so in the future. As a result of the selection process for workshop attendance, the study could not demonstrate definitively that the Health Careers Workshops Program contributed to the recruitment of health professionals. However, it has shown that the Program contributed significantly not only to the retention of those interested in the health industry but to the return of trained health professionals to rural and regional areas. The benefit to the health industry from these workshops has been substantial in relation to the small amount of funds invested