Synthesis, crystal structure, and DFT study of two new dinuclear copper(I) complexes bearing Ar-BIAN ligands functionalized with NO2 groups

Two new bis(aryl-imino)-acenaphthene, Ar-BIAN (Ar = 2,4,6-trimethylphenyl = mes) ligands, bearing the NO2 group in the naphthalene moiety of the iminoacenaphthene at para- (5-NO2) and meta- (4-NO2) position, of formulations 1,2-bis(mes-imino)-5-nitroacenaphthene, 1, and 1,2-bis(mes-imino)-4-nitroacenaphthene, 2, were synthesized. Their respective dinuclear iodide bridged copper(I) complexes [Cu2(μ-I)2(mes-BIAN-5-NO2)2], 3 and [Cu2(μ-I)2(mes-BIAN-4-NO2)2], 4, were obtained in good yields by treatment with an equimolar amount of CuI. All compounds were characterized by elemental analysis, single-crystal X-ray diffraction, 1H-NMR, 13C-NMR, FTIR, UV/Vis spectroscopy. DFT calculations helped to understand the different molecular structure observed in the crystals of 3 and 4 and the determining role of packing forces. TDDFT revealed that the absorption bands in the visible were essentially MLCT (Metal to Ligand Charge Transfer), with some n→π* character (intra ligand). The shift to the red compared to the spectrum of the Cu(I) complex analogue without the NO2 group, [Cu2(μ-I)2](mes-BIAN)2], 6, could be explained by the stabilization of the ligand unoccupied π* orbitals in the presence of NO2.info:eu-repo/semantics/publishedVersio

Synthesis and characterization of chromium(III), manganese(ll), iron(III), cobalt(ll), nickel(ll), copper(II), cadmium(ll) and dioxouranium(VI) complexes of 4(2-pyridyl )-1-(2,4-dihydroxybenzaldehyde )-3-thiosemicarbazone

914-918A few complexes of Cr(III), Mn(II), Fe(III), Co(II), Ni(II), Cu(II),Zn(II), Cd(II) and dioxouranium(VJ) with 4(2-pyridyl)-1-(2,4-dihydroxybenzaldehyde)-3-thiosemicarbazone have been synthesised and characterized on the basis of elemental analysis, IR, electronic NMR, and magnetic moment data. An octahedral structure is proposed for the Cr(III), Fe(III),Co(II)and Ni(H3PBT)2Cl2.2H2O complexes; a tetrahedral structure for the Mn(II) and Ni2(PBT)OAc.H2O complexes and a square planar structure for .the Cu(II) complexes. The antimicrobial and antifungal activities of H3PBT and of its metal(II) complexes are investigated. The results reveal that H3PBT exhibits greater antimicrobial activities than its complexes

Photochemical and DNA degradation studies on tenoxicam, lornoxicam, and their photolysis products

Elghamry I, El-Ayaan U, Youssef MM, Al-Shihry S, Letzel M, Mattay J. Photochemical and DNA degradation studies on tenoxicam, lornoxicam, and their photolysis products. Monatshefte für Chemie. 2017;148(2):257-262.Tenoxicam and lornoxicam are nonsteroidal anti-inflammatory drugs, were subjected to photoirradiation at 254 nm led to the photodegradation of the pharmaceutical agents. Both, the isolated photodegradation products and the pharmaceutical agents were examined toward DNA binding and degradation. The photodegradation products degrade calf thymus in concentration dependent manner