5,522 research outputs found

    EP-1372: Characterization of the new Single Layer Diamond detector

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    A non-dispersive Raman D-band activated by well-ordered interlayer interactions in rotationally stacked bi-layer Graphene

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    Raman measurements on monolayer graphene folded back upon itself as an ordered but skew-stacked bilayer (i.e. with interlayer rotation) presents new mechanism for Raman scattering in sp2 carbons that arises in systems that lack coherent AB interlayer stacking. Although the parent monolayer does not exhibit a D-band, the interior of the skewed bilayer produces a strong two-peak Raman feature near 1350 cm-1; one of these peaks is non-dispersive, unlike all previously observed D-band features in sp2 carbons. Within a double-resonant model of Raman scattering, these unusual features are consistent with a skewed bilayer coupling, wherein one layer imposes a weak but well-ordered perturbation on the other. The discrete Fourier structure of the rotated interlayer interaction potential explains the unusual non-dispersive peak near 1350 cm-1

    Lean-inspired development work in agriculture: Implications for the work environment

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    Farmers operate in a turbulent environment that includes international competition, weather conditions and animal behaviour, for example, and is difficult for them to control. However, economy and productivity always have a high priority. As a consequence, farms have started to implement lean-inspired work systems. At the same time, health and safety are of urgent concern in the sector. This article explores how famers apply lean-inspired work processes. It identifies work environment changes during and after a lean implementation, as well as possible developments in the work environment following implementation of the lean philosophy. Data were collected from three groups: lean, lean-light and development-inclined reference farms (in total 54 farms), using a questionnaire and interviews. The results indicate that a majority of the lean farms were applying several lean principles and tools, and the lean philosophy. The leanlight farms applied parts of the lean concept, while the reference farms applied some of the more general tools, used in lean and elsewhere, such as visualisation in various forms and to various extents. The results showed positive effects of lean on the psychosocial work environment, better work structure and improved information, communication and co-operation. The physical work environment was improved to some extent by lean, where advantages such as a more structured and practical work environment with less physical movements and locomotion could be noticed. The lean concept provided a more structured and systematic approach to dealing with work and production environmental issues, for managers as well as for employees

    2000 Oregon Vineyard Report

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    This statewide survey report on vineyards and wineries in Oregon covers bearing and nonbearing acres, size of vineyard operation, variety and county, size distribution, prices, yields, crush, inventory, and sales. The report also contains some comparisons of data for 1999 and 2000. According to this report, wine grape production and production value set record highs for the industry

    2000 Oregon Winery Report

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    This statewide survey report on Oregon wineries covers crush, equivalent wine production, inventory and equivalent inventory, and sales. The report also contains some comparisons of data for 1999 and 2000. According to this report, total sales increased by 27% from the previous year

    Osteoarthritis and Toll-Like Receptors: When Innate Immunity Meets Chondrocyte Apoptosis

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    Osteoarthritis (OA) has long been viewed as a degenerative disease of cartilage, but accumulating evidence indicates that inflammation has a critical role in its pathogenesis. In particular, chondrocyte-mediated inflammatory responses triggered by the activation of innate immune receptors by alarmins (also known as danger signals) are thought to be involved. Thus, toll-like receptors (TLRs) and their signaling pathways are of particular interest. Recent reports suggest that among the TLR-induced innate immune responses, apoptosis is one of the critical events. Apoptosis is of particular importance, given that chondrocyte death is a dominant feature in OA. This review focuses on the role of TLR signaling in chondrocytes and the role of TLR activation in chondrocyte apoptosis. The functional relevance of TLR and TLR-triggered apoptosis in OA are discussed as well as their relevance as candidates for novel disease-modifying OA drugs (DMOADs).Peer reviewe

    Osteoarthritis and Toll-Like Receptors: When Innate Immunity Meets Chondrocyte Apoptosis

    Get PDF
    Osteoarthritis (OA) has long been viewed as a degenerative disease of cartilage, but accumulating evidence indicates that inflammation has a critical role in its pathogenesis. In particular, chondrocyte-mediated inflammatory responses triggered by the activation of innate immune receptors by alarmins (also known as danger signals) are thought to be involved. Thus, toll-like receptors (TLRs) and their signaling pathways are of particular interest. Recent reports suggest that among the TLR-induced innate immune responses, apoptosis is one of the critical events. Apoptosis is of particular importance, given that chondrocyte death is a dominant feature in OA. This review focuses on the role of TLR signaling in chondrocytes and the role of TLR activation in chondrocyte apoptosis. The functional relevance of TLR and TLR-triggered apoptosis in OA are discussed as well as their relevance as candidates for novel disease-modifying OA drugs (DMOADs).Peer reviewe
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