33 research outputs found

    Conventionalism

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    Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Linguistics and Philosophy, 2003.Includes bibliographical references (leaves 99-101).Certain fundamental philosophical disputes, in contrast to disputes in the empirical sciences, are characterized by the persistence of disagreement. This has led some to endorse conventionalism, the view that the 'facts of the matter' partly depend on our conventions and that disagreements persist because both sides to the dispute employ different conventions. What does it mean to say that the facts of the matter partly depend on conventions? My thesis is concerned with this question. It has four parts. Part I ('Convention, Dependence, Covariance') examines how some matters of fact may depend on convention. I argue that while versions of conventionalism which can be construed in terms of one of the familiar dependence-relations are intuitively plausible, most interesting versions of conventionalism (about, say, ontology, modality and morality) cannot be so construed. To maintain the claim that some range of facts depends on convention, conventionalists need to explain how the features they take to be conventionally determined systematically covary with conventions. Part II ('A Framework for Conventionalist Reasoning') provides the formal tools to model conventionalist dependence-relations, tools that respect the methodological assumptions of conventionalists and reflect the logic of conventionalist discourse.(cont.) The framework developed is also useful for perspicuously formulating other philosophical accounts that take some aspect of reality to depend on human practices, such as neo-Kantian, projectivist and response-dependence accounts. Part III ('Facts by Convention') investigates how to make philosophical sense of the dependence-relations invoked by conventionalists. I critically examine several conventionalist accounts in the literature, and, employing the tools developed in part II, I propose various explications of how a range of facts may depend on convention. Part IV ('Putting everything together') classifies conventionalist accounts according to what kind of dependence-relation they invoke and critically discusses the interest and plausibility of ontological conventionalism.by Iris Einheuser.Ph.D

    Nonexistence, Vague Existence, Merely Possible Existence

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    This paper explores a new non-deflationary approach to the puzzle of nonexistence and its cousins. On this approach, we can, under a plausible assumption, express true de re propositions about certain objects that don't exist, exist indeterminately or exist merely possibly. The defense involves two steps: First, to argue that if we can actually designate what individuates a nonexistent target object with respect to possible worlds in which that object does exist, then we can express a de re proposition about "it". Second, to adapt the concept of outer truth with respect to a possible world ā€“ a concept familiar from actualist modal semantics ā€“ for use in representing the actual world

    Der CMV Serostatus correliert mit einem verkĆ¼rzten Ɯberleben bei Patienten mit Glioblastom

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    Effect of Direct Oral Anticoagulants on Treatment of Geriatric Hip Fracture Patients: An Analysis of 15,099 Patients of the AltersTraumaRegister DGU<sup>Ā®</sup>

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    Background and Objectives: The increased use of direct oral anticoagulants (DOACs) results in an increased prevalence of DOAC treatment in hip fractures patients. However, the impact of DOAC treatment on perioperative management of hip fracture patients is limited. In this study, we describe the prevalence of DOAC treatment in a population of hip fracture patients and compare these patients with patients taking vitamin K antagonists (VKA) and patients not taking anticoagulants. Materials and Methods: This study is a retrospective analysis from the Registry for Geriatric Trauma (ATR-DGU). The data were collected prospectively from patients with proximal femur fractures treated between January 2016 and December 2018. Among other factors, anticoagulation was surveyed. The primary outcome parameter was time-to-surgery. Further parameters were: type of anesthesia, surgical complications, soft tissue complications, length of stay and mortality. Results: In total, 11% (n = 1595) of patients took DOACs at the time of fracture, whereas 9.2% (n = 1325) were on VKA therapy. During the study period, there was a shift from VKA to DOACs. The time-to-surgery of patients on DOACs and of patients on VKA was longer compared to patients who did not take any anticoagulation. No significant differences with regard to complications, type of anesthesia and mortality were found between patients on DOACs compared to VKA treatment. Conclusion: An increased time-to-surgery in patients taking DOACs and taking VKA compared to non-anticoagulated patients was found. This underlines the need for standardized multi-disciplinary orthopedic, hematologic and ortho-geriatric algorithms for the management of hip fracture patients under DOAC treatment. In addition, no significant differences regarding complications and mortality were found between DOAC and VKA users. This demonstrates that even in the absence of widely available antidotes, the safe management of geriatric patients under DOACs with proximal femur fractures is possible
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