12 research outputs found
A multidimensional QoE monitoring system for audiovisual and haptic interactive IP communications
Application of a Live Attenuated Varicella Vaccine to Hospitalized Children and Its Protective Effect on Spread of Varicella Infection
Indole Synthesis via Cyclative Formation of 2,3-Dizincioindoles and Regioselective Electrophilic Trapping
Upon
zincation of two acidic protons attached to the nitrogen and
the sp-carbon atoms, a <i>N-</i>protected 2-ethynylaniline
cyclizes to a 2,3-dizincioindole at 120 °C. Driven by the energy
gain due to formation of two C–Zn bonds, this reaction occurs
smoothly without side reactions, although this transformation is intrinsically
endothermic in its bare anionic form. The resulting dizinc intermediate
can be functionalized with one or two different electrophiles either
inter- or intramolecularly on either C<sup>2</sup> or C<sup>3</sup> selectively, depending on the choice of catalyst and the electrophiles.
This conversion of 2-ethynylaniline to 2,3-dimetalloindole can be
applied to an expeditious synthesis of indenoindolone and benzodipyrrole
derivatives, which are compounds of interest for medicinal chemistry
and materials science, respectively
Application of a Live Attenuated Varicella Vaccine to Hospitalized Children and Its Protective Effect on Spread of Varicella Infection
Conical Ionic Amphiphiles Endowed with Micellization Ability but Lacking Air–Water and Oil–Water Interfacial Activity
Micellization in
water and reduction of the surface tension at
water interfaces with air and oil are two archetypical properties
of surfactants, caused by self-aggregation and Gibbs monolayer formation
at the interfaces, respectively. We present here a new type of amphiphiles
that possess a conical shape consisting of a hydrophobic apex and
five ionic termini at the base of the cone. The conical shape and
the high charge density cooperatively impede monolayer formation at
the interfaces, hence preventing foaming and emulsification. On the
other hand, the conical shape strongly assists micelle formation in
water and hemimicelle formation on a solid surface to promote dissolution
of nanoparticles such as magnetic nanoparticles and nanocarbons in
water. The well-defined shape and charge locations distinguish the
new amphiphiles from known polymer amphiphiles that show similar surface
activity