A New Catalogue of Galactic Novae: Investigation of the MMRD relation & Spatial Distribution

In this study, a new Galactic novae catalogue is introduced collecting important parameters of these sources such as their light curve parameters, classifications, full width half maximum (FWHM) of H$_\alpha$ line, distances and interstellar reddening estimates. The catalogue is also published on a website with a search option via a SQL query and an online tool to re-calculate the distance/reddening of a nova from the derived reddening-distance relations. Using the novae in the catalogue, the existence of a maximum magnitude-rate of decline (MMRD) relation in the Galaxy is investigated. Although an MMRD relation was obtained, a significant scattering in the resulting MMRD distribution still exists. We suggest that the MMRD relation likely depends on other parameters in addition to the decline time, as FWHM H$_\alpha$, the light curve shapes. Using two different samples depending on the distances in the catalogue and from the derived MMRD relation, the spatial distributions of Galactic novae as a function of their spectral and speed classes were studied. The investigation on the Galactic model parameters implies that best estimates for the local outburst density are 3.6 and 4.2 $\times 10^{-10}$ pc$^{-3}$ yr$^{-1}$ with a scale height of 148 and 175 pc, while the space density changes in the range of $0.4 - 16 \ \times 10^{-6}$ pc$^{-3}$. The local outburst density and scale height obtained in this study infer that the disk nova rate in the Galaxy is in the range of $\sim20$ to $\sim100$ yr$^{-1}$ with an average estimate $67^{+21}_{-17}$ yr$^{-1}$.Comment: 24 pages, 9 figures, 6 tables; Accepted for publication in MNRAS on 13 Feb 201

Comparison of botox and lateral internal sphincterotomy treatment outcomes in chronic anal fissures

Objective: Both botox and lateral internal sfinkterotomi are treatment technics used in chronic anal fissure; provide the relaxation of anal sphincter and as a result of this, healing occurs. Aim of this study is to compare efficacy of botox and LIS treatment in chronic anal fissure and discussing with the literature. Methods: 60 of 66 patients who has chronic anal fissure, that we reached, treated but not healed with medical therapy, appealed to the Dr. Sami Ulus Hospital included the study. Gender, age, fissure localization, complaints (pain, bleeding, itching, constipation), complaint length, recurrences after treatment, continence conditions and complications of patients were registered. Results: Sixty patients were enrolled the study. Of the 60 patients; 38(63.3%) were male and 22 (27.7%) were female. Mean age of all patients was 35.93 ± 11.45 (21 -60). Pain was the common complaint of the all patients. 10 (32.3%) recurrence were detected in botox treatment group (Group-I), only 1 (3.4%) recurrence was in LIS group (Group-II). There was no complication as an incontinence in group-I but 3 cases with incontinence (10.39%) were obtained in group-II. In the evaluation of these 3 cases by Cleveland Clinic Continence Scoring System, 2 cases classified as gas incontinence and 1 case as moderate fecal incontinence. Conclusion: Although botulinum toxin injection seen as an alternative treatment method with low complication rates such as incontinence, high recurrence is an important shortcoming of this technic. LIS performed by experienced surgeons remained the most popular treatment modality with low complication rates and great deal of healing success

İstabul Üniversitesi gözlemevi odak düzlemi aygıtı test ve karakterizasyon laboratuvarı

Doğu Anadolu Gözlemevi Odak Düzlemi Aygıtları ve Adaptif Optik Sistemi başlıklı, 2016K121370 numaralı T.C. Kalkınma Bakanlığı projesi ve İstanbul Üniversitesi Rektörlüğü desteğinde yürüyen çalışmalar kapsamında İstanbul Üniversitesi Astronomi ve Uzay Bilimleri Bölümü’nde teleskop odak düzlemi aygıtı test ve karakterizasyon laboratuvarı kurulum çalışmaları başlatılmıştır. Başta DAG Teleskobu olmak üzere ülkemizdeki tüm gözlemevlerine hizmet verebilecek şekilde tasarlanan laboratuvar, CCD kamera, filtre ve odak düzlemi aygıtları için bir test masasına sahip olacaktır. Bu sunumda, laboratuvarın kurulumu ve alımlarında gelinen son noktanın yanı sıra, İstanbul Üniversitesi Fizik Bölümü Nano-Optoelektronik Araştırma Laboratuvarları ile birlikte yapılması planlanan çalışmalar sunulacaktır.Publisher's Versio

Different epidemiology of bloodstream infections in COVID-19 compared to non-COVID-19 critically ill patients: A descriptive analysis of the Eurobact II study

Background: The study aimed to describe the epidemiology and outcomes of hospital-acquired bloodstream infections (HABSIs) between COVID-19 and non-COVID-19 critically ill patients. Methods: We used data from the Eurobact II study, a prospective observational multicontinental cohort study on HABSI treated in ICU. For the current analysis, we selected centers that included both COVID-19 and non-COVID-19 critically ill patients. We performed descriptive statistics between COVID-19 and non-COVID-19 in terms of patients’ characteristics, source of infection and microorganism distribution. We studied the association between COVID-19 status and mortality using multivariable fragility Cox models. Results: A total of 53 centers from 19 countries over the 5 continents were eligible. Overall, 829 patients (median age 65 years [IQR 55; 74]; male, n = 538 [64.9%]) were treated for a HABSI. Included patients comprised 252 (30.4%) COVID-19 and 577 (69.6%) non-COVID-19 patients. The time interval between hospital admission and HABSI was similar between both groups. Respiratory sources (40.1 vs. 26.0%, p < 0.0001) and primary HABSI (25.4% vs. 17.2%, p = 0.006) were more frequent in COVID-19 patients. COVID-19 patients had more often enterococcal (20.5% vs. 9%) and Acinetobacter spp. (18.8% vs. 13.6%) HABSIs. Bacteremic COVID-19 patients had an increased mortality hazard ratio (HR) versus non-COVID-19 patients (HR 1.91, 95% CI 1.49–2.45). Conclusions: We showed that the epidemiology of HABSI differed between COVID-19 and non-COVID-19 patients. Enterococcal HABSI predominated in COVID-19 patients. COVID-19 patients with HABSI had elevated risk of mortality. Trial registration ClinicalTrials.org number NCT03937245. Registered 3 May 2019

Impact of opioid-free analgesia on pain severity and patient satisfaction after discharge from surgery: multispecialty, prospective cohort study in 25 countries

Background: Balancing opioid stewardship and the need for adequate analgesia following discharge after surgery is challenging. This study aimed to compare the outcomes for patients discharged with opioid versus opioid-free analgesia after common surgical procedures.Methods: This international, multicentre, prospective cohort study collected data from patients undergoing common acute and elective general surgical, urological, gynaecological, and orthopaedic procedures. The primary outcomes were patient-reported time in severe pain measured on a numerical analogue scale from 0 to 100% and patient-reported satisfaction with pain relief during the first week following discharge. Data were collected by in-hospital chart review and patient telephone interview 1 week after discharge.Results: The study recruited 4273 patients from 144 centres in 25 countries; 1311 patients (30.7%) were prescribed opioid analgesia at discharge. Patients reported being in severe pain for 10 (i.q.r. 1-30)% of the first week after discharge and rated satisfaction with analgesia as 90 (i.q.r. 80-100) of 100. After adjustment for confounders, opioid analgesia on discharge was independently associated with increased pain severity (risk ratio 1.52, 95% c.i. 1.31 to 1.76; P &lt; 0.001) and re-presentation to healthcare providers owing to side-effects of medication (OR 2.38, 95% c.i. 1.36 to 4.17; P = 0.004), but not with satisfaction with analgesia (beta coefficient 0.92, 95% c.i. -1.52 to 3.36; P = 0.468) compared with opioid-free analgesia. Although opioid prescribing varied greatly between high-income and low- and middle-income countries, patient-reported outcomes did not.Conclusion: Opioid analgesia prescription on surgical discharge is associated with a higher risk of re-presentation owing to side-effects of medication and increased patient-reported pain, but not with changes in patient-reported satisfaction. Opioid-free discharge analgesia should be adopted routinely

Erişkin kalça displazisinin değerlendirilmesinde normal radyolojik ölçüm değerleri; Anadolu toplumunda 1732 sağlıklı kalçanın değerlendirilmesi

Objectives: The purpose of this study is to determine the normal values of radiographic measurements used for the assessment of hip joint, particularly focusing on the hip dysplasia, on healthy young adults in Anatolian population. Materials and methods: This prospective study consisted 866 subjects ( > 18 years of age) without clinical evidence of hip disorder who underwent anterior-posterior (AP) x-ray of pelvic region for routine screening in our institution. Acetabular angle of Sharp, center edge angle, ACM angle, acetabular index, and Reimer's migration index were measured. Normative data regarding radiographic parameters were presented for both gender and body side and statistical comparison was performed between gender and body sides. Results: CE angles (M: 30.3±3.4 vs F: 28.8±2.7) and ACM (M: 41.0±1.8 vs F: 40.5±1.8) angles were higher in male subjects; AI (M: 3.5±0.6 vs F: 3.8±0.9) and Sharp angle (M: 37.9±2.5 vs F: 38.5±2.1) was higher in female subjects. Reimer's migration index was similar between genders (M: 12.6±3.5 vs F: 13.0±3.6). All measured variables were statistically different between body sides, except AI in male subjects. Conclusion: We emphasize that normal limits of acetabular angles obtained from our own population should be used as reference values in various orthopedic operations regarding acetabular region.Çalışmanın amacı, sağlıklı Anadolu insanında kalça ekleminin, özellikle de kalça displazinin değerlendirilmesi amacı ile normal radyolojik parametrelerinin saptanmasıdır. Hastalar ve metot: Prospektif olarak yapılan çalışmamıza, klinik olarak herhangi kalça rahatsızlığı bulunmayan ve merkezimizde rutin tarama amaçlı pelvik bölgeyi içeren, ön-arka direkt grafisi çekilmiş 866 erişkin hasta ( 18 yaşından büyük) dahil edilmiştir. Asetabular Sharp açısı, CE açısı, asetabular indeks (AI), ACM açısı ve Reimer’in migrasyon indeksi standart radyografiler üzerinden ölçüldü. Her iki cinsiyet ve her iki taraf kalça için ayrı olarak normal değerler saptanıp istatistiksel karşılaştırma yapılmıştır. Sonuçlar: CE (E: 30.3±3.4 - K: 28.8±2.7) ve ACM açıları (E: 41.0±1.8 - K: 40.5±1.8) erkek hastalarda istatistiksel olarak yüksek iken; AI (E: 3.5±0.6 -K: 3.8±0.9) ve Sharp açıları (E: 37.9±2.5 -K: 38.5±2.1) bayanlarda daha fazla idi. Reimer’in migrasyon indeksi cinsiyetler arasında benzer değerlere sahipti (E: 12.6±3.5-K: 13.0±3.6). Erkek hastalardaki AI (asetabular indeks) açıları haricinde tüm parametreler her iki cinste de sağ ve sol kalça için farklı idi. Çıkarımlar: Asetabular bölgeyi içeren ortopedik cerrahi işlemlerde kendi toplumumuzdan elde edilmiş normal asetabular açı değerlerinin kullanılmasını vurgulamaktayız

Memory Encryption for Smart Cards

Part 5: Implementations and Hardware Security 2International audienceWith the latest advances in attack methods, it has become increasingly more difficult to secure data stored on smart cards, especially on non-volatile memories (NVMs), which may store sensitive information such as cryptographic keys or program code. Lightweight and low-latency cryptographic modules are a promising solution to this problem. In this study, memory encryption schemes using counter (CTR) and XOR-Encrypt-XOR (XEX) modes of operation are adapted for the target application, and utilized using various implementations of the block ciphers AES and PRESENT. Both schemes are implemented with a block cipher-based address scrambling scheme, as well as a special write counter scheme in order to extend the lifetime of the encryption key in CTR-mode. Using the lightweight cipher PRESENT, it is possible to implement a smart card NVM encryption scheme with less than 6K gate equivalents and zero additional latency

Predicción de la presencia del tendón del músculo plantar mediante el examen del tendón del músculo palmar largo. ¿hay una relación?

WOS: 000339241600035The purpose of this study was to investigate the relationship between palmaris longus (PL) and plantaris (P) tendons and test the clinical usefulness of symmetry patterns between these tendons in Turkish population. This prospective study comprised a total of 240 adult patients (120 men and 120 women) who were admitted to our outpatient clinic with bilateral knee complaints that required bilateral knee MR examination during two years. Standard test (Schaefer's test, oppose the thumb to the little finger while flexing the wrist) was used to assess the presence of the PL tendon both with inspection and palpation. Knee MRI was used to determine the presence of P muscle belly on both sides. We have analyzed symmetric distribution pattern using Mc-Nemar test. The PL was absent unilaterally in 34 subjects (14.2%), while it was absent bilaterally in 17 subjects (7.1%). The P was absent unilaterally in 51 subjects (21.3%), while it was absent bilaterally in 10 subjects (4.2%). If PL was absent in one hand, the chance of having an ipsilateral P tendon was 70.6%. If PL was present in one hand, the chance of having an ipsilateral P tendon was 87.6%. The Mc-Nemar test for symmetry yielded a p value of 0.841 for ipsilateral PL and P muscles. A clear-cut link between Palmaris longus and plantaris tendons could not be demonstrated in this study. Both muscles show different variations independent from each other.El propósito de este estudio fue investigar la relación entre los tendones del músculo palmar largo (MPL ) y músculo plantar (MP) y poner a prueba la utilidad clínica de los patrones de simetría entre estos tendones de la población turca. Estudio prospectivo realizado sobre 240 pacientes adultos (120 hombres y 120 mujeres) que ingresaron en la clínica por síntomas de dolor en la rodilla bilateralmente, quienes requerían un examen de RM de rodilla durante dos años. Se utilizó la prueba estándar (prueba de Schaefer, se oponen el pulgar hasta el dedo mínimo, mientras se flexiona la muñeca) para evaluar la presencia del tendón MPL tanto con la inspección y palpación. La RM de la rodilla se utilizó para determinar la presencia de vientre muscular plantar en ambos lados. Se analizó el patrón de distribución simétrica mediante la prueba de McNemar. El tendón del MPL estuvo ausente de manera unilateral en 34 pacientes (14,2%) y bilateralmente en 17 pacientes (7,1%). El tendón del MP estuvo ausente de manera unilateral en 51 pacientes ( 21,3 %) mientras que bilateralmente no estaba en 10 pacientes (4,2%). Si el tendón del MPL estuvo ausente en un lado, la probabilidad de tener un tendón del MP ipsilateral fue del 70,6 %. Si el tendón del MPL estaba presente en un lado, la probabilidad de tener un tendón del MP ipsilateral fue 87,6%. La prueba de McNemar - simetría produjo un valor p de 0,841 para los músculos PL y P ipsilaterales. Una relación directa claro entre los tendones de los músculos PL y P no se pudo demostrar en este estudio. Ambos músculos muestran diferentes variaciones independiente uno del otro

Team #2: Team T&T Presentation: PowerPoint Presentation

For the presentation: Goals? – how some of the success ingredients work out for a team. – have fun

Reconstruction of intercalary bone defects following bone tumor resection with segmental bone transport using an Ilizarov circular external fixator

WOS: 000345389200023PubMed ID: 25146001Aim The purpose of this retrospective study was to report the long-term follow-up results of the reconstruction of bony defects with Ilizarov distraction osteogenesis using the bone transport method following en bloc resection of bone tumors. Materials and methods En bloc resection was performed in 13 patients with bone tumors between October 1991 and December 2010 in our clinic. The mean age of the patients was 19.46 years (range 7-42 years) at the time of surgery. Histological diagnosis was osteosarcoma in seven cases, Ewing's sarcoma in three cases, giant cell tumor in one case, osteoblastoma in one case and fibrous dysplasia in one case. In all cases either the femur or tibia was involved. Results The average follow-up period was 157.23 months (range 32-288 months), and the bone defect after resection was 14.61 cm +/- (9-24 cm). The mean Musculoskeletal Tumor Society score of the patients was 89.46 (83-96) at the final follow-up. The mean Knee Society Scale scores of patients in whom reconstruction was performed around the knee joint were 74.3 (51-84). The mean foot and ankle disability index of patients with a tumor around the ankle joint was 81 (73-95). Quality of life of the patients according to the SF-36 and BQUILI indexes was scored as 104 (88-150) and 4 (0-13), respectively. Conclusion From the long-term follow-up results, reconstruction with distraction osteogenesis seems to be an efficient method in patients with long life expectancies. However, a long external fixation time is a disadvantage of this technique. Problems in patient compliance and possible complications such as nonunion should be managed promptly