Indochina birds

17 p. : map ; 24 cm.Includes bibliographical references (p. 17)."A brief account is given of the nature of the expedition and an itinerary is appended with coordinates. Comments are made on 13 forms of which three are new to Tonkin, two new to central Laos and four new to southern Laos. The validity of the race Pitta soror annamensis is also discussed"--P. 16

Superhumps in Cataclysmic Binaries. XXIII. V442 Ophiuchi and RX J1643.7+3402

We report the results of long observing campaigns on two novalike variables: V442 Ophiuchi and RX J1643.7+3402. These stars have high-excitation spectra, complex line profiles signifying mass loss at particular orbital phases, and similar orbital periods (respectively 0.12433 and 0.12056 d). They are well-credentialed members of the SW Sex class of cataclysmic variables. Their light curves are also quite complex. V442 Oph shows periodic signals with periods of 0.12090(8) and 4.37(15) days, and RX J1643.7+3402 shows similar signals at 0.11696(8) d and 4.05(12) d. We interpret these short and long periods respectively as a "negative superhump" and the wobble period of the accretion disk. The superhump could then possibly arise from the heating of the secondary (and structures fixed in the orbital frame) by inner-disk radiation, which reaches the secondary relatively unimpeded since the disk is not coplanar. At higher frequencies, both stars show another type of variability: quasi-periodic oscillations (QPOs) with a period near 1000 seconds. Underlying these strong signals of low stability may be weak signals of higher stability. Similar QPOs, and negative superhumps, are quite common features in SW Sex stars. Both can in principle be explained by ascribing strong magnetism to the white dwarf member of the binary; and we suggest that SW Sex stars are borderline AM Herculis binaries, usually drowned by a high accretion rate. This would provide an ancestor channel for AM Hers, whose origin is still mysterious.Comment: PDF, 41 pages, 4 tables, 16 figures; accepted, in press, to appear December 2002, PASP; more info at http://cba.phys.columbia.edu

An early years toolbox for assessing early executive function, language, self-Regulation, and social development validity, reliability, and preliminary norms

Several methods of assessing executive function (EF), self-regulation, language development, and social development in young children have been developed over previous decades. Yet new technologies make available methods of assessment not previously considered. In resolving conceptual and pragmatic limitations of existing tools, the Early Years Toolbox (EYT) offers substantial advantages for early assessment of language, EF, self-regulation, and social development. In the current study, results of our large-scale administration of this toolbox to 1,764 preschool and early primary school students indicated very good reliability, convergent validity with existing measures, and developmental sensitivity. Results were also suggestive of better capture of children’s emerging abilities relative to comparison measures. Preliminary norms are presented, showing a clear developmental trajectory across half-year age groups. The accessibility of the EYT, as well as its advantages over existing measures, offers considerably enhanced opportunities for objective measurement of young children’s abilities to enable research and educational applications

1962

Turf on the Launching Pad (page 1) Turf management Club News (3) Education, Experience and Attitude (4) A Blade of Grass (5) Picture - Professor Lawrence S. Dickinson (6) Picture - Thomas Mascaro - Banquet Speaker (7) Planting Trees on the Golf Course (8) Two-Way Radios (8) Greens Mowing Procedure (9) Watering and Topdressing as Related to Poa annua Infestations (10) Picture - Stockbridge Majors in Turf Management (12) Picture - Graduates of Winter School for Turf Managers - 1962 (13) Review of Season\u27s Pests by Joseph Troll (A-1) Today\u27s Trends in Golf Course Development by Col. Harry C. Eckoff (A-3) Breeding and Selection of Fine Turf Grasses by Dr. B. R. Anderson Penncross Bentgrass by J. Dutch(A-13) Poa annua by Alexander Radko (A-16) Velvet Bent by Jesse DeFrance (A-19) Vegetative Creeping Bentgrasses by Fred Grau (A-21) Modification of SOils for Green Construction & Top Dressing by Prof. H. B. Musser (A-27) Soil COmpaction by Donald Waddington (A-32) Irrigation Practices and the Need of Basic Research by Prof. Edward PIra (A-36) Water Sources by Z. Mills (A-39) Athletic Field Maintenance by Thomas Mascaro (A-41) Planning the Landscape Around the House by Prof. Harold Mosher (A-43

Clustering of the IR Background Light with Spitzer: Contribution from Resolved Sources

We describe the angular power spectrum of resolved sources at 3.6 microns (L-band) in Spitzer imaging data of the GOODS HDF-N, the GOODS CDF-S, and the NDWFS Bootes field in several source magnitude bins. We also measure angular power spectra of resolved sources in the Bootes field at K_S and J-bands using ground-based IR imaging data. In the three bands, J, K_S, and L, we detect the clustering of galaxies on top of the shot-noise power spectrum at multipoles between ell ~ 10^2 and 10^5. The angular power spectra range from the large, linear scales to small, non-linear scales of galaxy clustering, and in some magnitude ranges, show departure from a power-law clustering spectrum. We consider a halo model to describe clustering measurements and to establish the halo occup ation number parameters of IR bright galaxies at redshifts around one. We also extend our clustering results and completeness-corrected faint source number counts in GOODS fields to understand the underlying nature of unresolved sources responsible for IR background (IRB) anisotropies that were detected in deep Spitzer images. While these unresolved fluctuations were measured at sub-arcminute angular scales, if a high-redshift diffuse component associated with first galaxies exists in the IRB, then it's clustering properties are best studied with shallow, wide-field images that allow a measurement of the clustering spectrum from a few degrees to arcminute angular scales.Comment: 12 pages, 11 figures. Accepted version in press with ApJ. Revised version includes conditional luminosity function models for IR galaxy LFs, counts and clustering spectra. The faint, unresolved galaxy counts in these models can reproduce excess anisotropy fluctuations reported in astro-ph/0511105. Conditional luminosity function code is available at http://www.cooray.org/lumfunc.html V3: Includes all data from astro-ph/0511105 in revised Fig.8 and minor changes to tex

LSST Science Book, Version 2.0

A survey that can cover the sky in optical bands over wide fields to faint magnitudes with a fast cadence will enable many of the exciting science opportunities of the next decade. The Large Synoptic Survey Telescope (LSST) will have an effective aperture of 6.7 meters and an imaging camera with field of view of 9.6 deg^2, and will be devoted to a ten-year imaging survey over 20,000 deg^2 south of +15 deg. Each pointing will be imaged 2000 times with fifteen second exposures in six broad bands from 0.35 to 1.1 microns, to a total point-source depth of r~27.5. The LSST Science Book describes the basic parameters of the LSST hardware, software, and observing plans. The book discusses educational and outreach opportunities, then goes on to describe a broad range of science that LSST will revolutionize: mapping the inner and outer Solar System, stellar populations in the Milky Way and nearby galaxies, the structure of the Milky Way disk and halo and other objects in the Local Volume, transient and variable objects both at low and high redshift, and the properties of normal and active galaxies at low and high redshift. It then turns to far-field cosmological topics, exploring properties of supernovae to z~1, strong and weak lensing, the large-scale distribution of galaxies and baryon oscillations, and how these different probes may be combined to constrain cosmological models and the physics of dark energy.Comment: 596 pages. Also available at full resolution at http://www.lsst.org/lsst/sciboo

Somatic Variants in SVIL in Cerebral Aneurysms

Publisher Copyright: © American Academy of Neurology.Background and ObjectivesWhile somatic mutations have been well-studied in cancer, their roles in other complex traits are much less understood. Our goal is to identify somatic variants that may contribute to the formation of saccular cerebral aneurysms.MethodsWe performed whole-exome sequencing on aneurysm tissues and paired peripheral blood. RNA sequencing and the CRISPR/Cas9 system were then used to perform functional validation of our results.ResultsSomatic variants involved in supervillin (SVIL) or its regulation were found in 17% of aneurysm tissues. In the presence of a mutation in the SVIL gene, the expression level of SVIL was downregulated in the aneurysm tissue compared with normal control vessels. Downstream signaling pathways that were induced by knockdown of SVIL via the CRISPR/Cas9 system in vascular smooth muscle cells (vSMCs) were determined by evaluating changes in gene expression and protein kinase phosphorylation. We found that SVIL regulated the phenotypic modulation of vSMCs to the synthetic phenotype via Krüppel-like factor 4 and platelet-derived growth factor and affected cell migration of vSMCs via the RhoA/ROCK pathway.DiscussionWe propose that somatic variants form a novel mechanism for the development of cerebral aneurysms. Specifically, somatic variants in SVIL result in the phenotypic modulation of vSMCs, which increases the susceptibility to aneurysm formation. This finding suggests a new avenue for the therapeutic intervention and prevention of cerebral aneurysms.Peer reviewe

The Hubble Higher-Z Supernova Search: Supernovae to z=1.6 and Constraints on Type Ia Progenitor Models

We present results from the Hubble Higher-z Supernova Search, the first space-based open field survey for supernovae (SNe). In cooperation with the Great Observatories Origins Deep Survey, we have used the Hubble Space Telescope with the Advanced Camera for Surveys to cover 300 square arcmin in the area of the Chandra Deep Field South and the Hubble Deep Field North on five separate search epochs (separated by 45 day intervals) to a limiting magnitude of z'=26. These deep observations have allowed us to discover 42 SNe in the redshift range 0.2 < z < 1.6. As these data span a large range in redshift, they are ideal for testing the validity of Type Ia supernova progenitor models with the distribution of expected ``delay times,'' from progenitor star formation to SN Ia explosion, and the SN rates these models predict. Through a Bayesian maximum likelihood test, we determine which delay-time models best reproduce the redshift distribution of SNe Ia discovered in this survey. We find that models that require a large fraction of ``prompt'' (less than 2 Gyr) SNe Ia poorly reproduce the observed redshift distribution and are rejected at 95% confidence. We find that Gaussian models best fit the observed data for mean delay times in the range of 3 to 4 Gyr.Comment: 32 pages, 15 figures, accepted for publication in the Astrophysical Journa

Molecular modeling of a tandem two pore domain potassium channel reveals a putative binding Site for general anesthetics

[Image: see text] Anesthetics are thought to mediate a portion of their activity via binding to and modulation of potassium channels. In particular, tandem pore potassium channels (K2P) are transmembrane ion channels whose current is modulated by the presence of general anesthetics and whose genetic absence has been shown to confer a level of anesthetic resistance. While the exact molecular structure of all K2P forms remains unknown, significant progress has been made toward understanding their structure and interactions with anesthetics via the methods of molecular modeling, coupled with the recently released higher resolution structures of homologous potassium channels to act as templates. Such models reveal the convergence of amino acid regions that are known to modulate anesthetic activity onto a common three- dimensional cavity that forms a putative anesthetic binding site. The model successfully predicts additional important residues that are also involved in the putative binding site as validated by the results of suggested experimental mutations. Such a model can now be used to further predict other amino acid residues that may be intimately involved in the target-based structure–activity relationships that are necessary for anesthetic binding