Founders, Feminists, and a Fascist -- Some Notable Women in the Missouri Section of the MAA

In the history of the Missouri Section of the MAA, some of the more interesting people who influenced the growth and development of the section through the years were and are women. In this chapter, we discuss the contributions of a few (certainly not all) of these women to the Missouri Section and mathematics as a whole, including Emily Kathryn Wyant (founder of KME), Margaret F. Willerding (who dealt with sexism in the 1940s), Maria Castellani (an official in Mussolini’s Italy before coming to America), and T. Christine Stevens (co-founder of Project NExT). Without them, and others like them, both mathematics and the Missouri Section of the MAA would be poorer

The DUNE far detector vertical drift technology. Technical design report

DUNE is an international experiment dedicated to addressing some of the questions at the forefront of particle physics and astrophysics, including the mystifying preponderance of matter over antimatter in the early universe. The dual-site experiment will employ an intense neutrino beam focused on a near and a far detector as it aims to determine the neutrino mass hierarchy and to make high-precision measurements of the PMNS matrix parameters, including the CP-violating phase. It will also stand ready to observe supernova neutrino bursts, and seeks to observe nucleon decay as a signature of a grand unified theory underlying the standard model. The DUNE far detector implements liquid argon time-projection chamber (LArTPC) technology, and combines the many tens-of-kiloton fiducial mass necessary for rare event searches with the sub-centimeter spatial resolution required to image those events with high precision. The addition of a photon detection system enhances physics capabilities for all DUNE physics drivers and opens prospects for further physics explorations. Given its size, the far detector will be implemented as a set of modules, with LArTPC designs that differ from one another as newer technologies arise. In the vertical drift LArTPC design, a horizontal cathode bisects the detector, creating two stacked drift volumes in which ionization charges drift towards anodes at either the top or bottom. The anodes are composed of perforated PCB layers with conductive strips, enabling reconstruction in 3D. Light-trap-style photon detection modules are placed both on the cryostat's side walls and on the central cathode where they are optically powered. This Technical Design Report describes in detail the technical implementations of each subsystem of this LArTPC that, together with the other far detector modules and the near detector, will enable DUNE to achieve its physics goals

Highly-parallelized simulation of a pixelated LArTPC on a GPU

The rapid development of general-purpose computing on graphics processing units (GPGPU) is allowing the implementation of highly-parallelized Monte Carlo simulation chains for particle physics experiments. This technique is particularly suitable for the simulation of a pixelated charge readout for time projection chambers, given the large number of channels that this technology employs. Here we present the first implementation of a full microphysical simulator of a liquid argon time projection chamber (LArTPC) equipped with light readout and pixelated charge readout, developed for the DUNE Near Detector. The software is implemented with an end-to-end set of GPU-optimized algorithms. The algorithms have been written in Python and translated into CUDA kernels using Numba, a just-in-time compiler for a subset of Python and NumPy instructions. The GPU implementation achieves a speed up of four orders of magnitude compared with the equivalent CPU version. The simulation of the current induced on 10^3 pixels takes around 1 ms on the GPU, compared with approximately 10 s on the CPU. The results of the simulation are compared against data from a pixel-readout LArTPC prototype

Whole-genome sequencing reveals host factors underlying critical COVID-19

Critical COVID-19 is caused by immune-mediated inflammatory lung injury. Host genetic variation influences the development of illness requiring critical care1 or hospitalization2,3,4 after infection with SARS-CoV-2. The GenOMICC (Genetics of Mortality in Critical Care) study enables the comparison of genomes from individuals who are critically ill with those of population controls to find underlying disease mechanisms. Here we use whole-genome sequencing in 7,491 critically ill individuals compared with 48,400 controls to discover and replicate 23 independent variants that significantly predispose to critical COVID-19. We identify 16 new independent associations, including variants within genes that are involved in interferon signalling (IL10RB and PLSCR1), leucocyte differentiation (BCL11A) and blood-type antigen secretor status (FUT2). Using transcriptome-wide association and colocalization to infer the effect of gene expression on disease severity, we find evidence that implicates multiple genes—including reduced expression of a membrane flippase (ATP11A), and increased expression of a mucin (MUC1)—in critical disease. Mendelian randomization provides evidence in support of causal roles for myeloid cell adhesion molecules (SELE, ICAM5 and CD209) and the coagulation factor F8, all of which are potentially druggable targets. Our results are broadly consistent with a multi-component model of COVID-19 pathophysiology, in which at least two distinct mechanisms can predispose to life-threatening disease: failure to control viral replication; or an enhanced tendency towards pulmonary inflammation and intravascular coagulation. We show that comparison between cases of critical illness and population controls is highly efficient for the detection of therapeutically relevant mechanisms of disease

Report to the New York State Cabbage Research Advisory Committee and Research Association, Nov. 1998

NYS IPM Type: Project ReportSix plant cuttings were propagated from each of 4 and 10 first and second backcross lines, respectively. The new plant lines were maintained in an experimental greenhouse (23-27?) at NYSAES. The parental lines, Sinapis alba and Brassica oleracea (cv. Rapid Cycling and Green Comet) were grown from seeds

Color, composition, and thermal environment of Kuiper Belt object (486958) Arrokoth

The outer Solar System object (486958) Arrokoth (provisional designation 2014 MU69) has been largely undisturbed since its formation. We studied its surface composition using data collected by the New Horizons spacecraft. Methanol ice is present along with organic material, which may have formed through irradiation of simple molecules. Water ice was not detected. This composition indicates hydrogenation of carbon monoxide-rich ice and/or energetic processing of methane condensed on water ice grains in the cold, outer edge of the early Solar System. There are only small regional variations in color and spectra across the surface, which suggests that Arrokoth formed from a homogeneous or well-mixed reservoir of solids. Microwave thermal emission from the winter night side is consistent with a mean brightness temperature of 29 ± 5 kelvin. ©2020NASA (contract no. NASW-02008)NASA (grant no. NAS5-97271 / TaskOrder30

Designing cowpea products for Northeastern Thailand

In ARCHIV YACIUK 4817

Introduction du niébé dans l'alimentation du Nord Est de la Thaïlande

Dans IDL-683

Neoteric Media as Tools for Process Intensification

© Published under licence by IOP Publishing Ltd. Process intensification (PI) is a commonly used term in the chemical processing industry. When the concept of PI was first introduced in the late 1970s within the Imperial Chemical Industries (ICI) company, the main impetus was to reduce the processing cost without impairing the production rate. Neoteric media present as alternatives in chemical processing include gas-expanded liquids, ionic liquids, subcritical water, and combination of gas-expanded liquids and ionic liquids. The applications of neoteric media include particle engineering for improved bioavailability, controlled release of therapeutic implants, pharmaceutical formulations, extraction of natural products, nano-carriers for drug delivery, sterilisation of implants, and chemical reactions. This paper provides an overview of the use of these neoteric media