363 research outputs found
Carotid Intima-Media Thickness and Cerebrovascular Disease in Community-Dwelling Older People Without Stroke
Computer-aided diagnosis for (123I)FP-CIT imaging: impact on clinical reporting
BACKGROUND: For (123I)FP-CIT imaging, a number of algorithms have shown high performance in distinguishing normal patient images from those with disease, but none have yet been tested as part of reporting workflows. This study aims to evaluate the impact on reporters' performance of a computer-aided diagnosis (CADx) tool developed from established machine learning technology. Three experienced (123I)FP-CIT reporters (two radiologists and one clinical scientist) were asked to visually score 155 reconstructed clinical and research images on a 5-point diagnostic confidence scale (read 1). Once completed, the process was then repeated (read 2). Immediately after submitting each image score for a second time, the CADx system output was displayed to reporters alongside the image data. With this information available, the reporters submitted a score for the third time (read 3). Comparisons between reads 1 and 2 provided evidence of intra-operator reliability, and differences between reads 2 and 3 showed the impact of the CADx. RESULTS: The performance of all reporters demonstrated a degree of variability when analysing images through visual analysis alone. However, inclusion of CADx improved consistency between reporters, for both clinical and research data. The introduction of CADx increased the accuracy of the radiologists when reporting (unfamiliar) research images but had less impact on the clinical scientist and caused no significant change in accuracy for the clinical data. CONCLUSIONS: The outcomes for this study indicate the value of CADx as a diagnostic aid in the clinic and encourage future development for more refined incorporation into clinical practice
Search for very high energy gamma-rays from WIMP annihilations near the Sun with the Milagro Detector
The neutralino, the lightest stable supersymmetric particle, is a strong
theoretical candidate for the missing astronomical ``dark matter''. A profusion
of such neutralinos can accumulate near the Sun when they lose energy upon
scattering and are gravitationally captured. Pair-annihilations of those
neutralinos may produce very high energy (VHE, above ) gamma-rays.
Milagro is an air shower array which uses the water Cherenkov technique to
detect extensive air showers and is capable of observing VHE gamma-rays from
the direction of the Sun with an angular resolution of . Analysis
of Milagro data with an exposure to the Sun of 1165 hours presents the first
attempt to detect TeV gamma-rays produced by annihilating neutralinos captured
by the Solar system and shows no statistically significant signal. Resulting
limits that can be set on gamma-ray flux due to near-Solar neutralino
annihilations and on neutralino cross-section are presented
X-ray variation statistics and wind clumping in Vela X-1
We investigate the structure of the wind in the neutron star X-ray binary
system Vela X-1 by analyzing its flaring behavior. Vela X-1 shows constant
flaring, with some flares reaching fluxes of more than 3.0 Crab between 20-60
keV for several 100 seconds, while the average flux is around 250 mCrab. We
analyzed all archival INTEGRAL data, calculating the brightness distribution in
the 20-60 keV band, which, as we show, closely follows a log-normal
distribution. Orbital resolved analysis shows that the structure is strongly
variable, explainable by shocks and a fluctuating accretion wake. Analysis of
RXTE ASM data suggests a strong orbital change of N_H. Accreted clump masses
derived from the INTEGRAL data are on the order of 5 x 10^19 -10^21 g. We show
that the lightcurve can be described with a model of multiplicative random
numbers. In the course of the simulation we calculate the power spectral
density of the system in the 20-100 keV energy band and show that it follows a
red-noise power law. We suggest that a mixture of a clumpy wind, shocks, and
turbulence can explain the measured mass distribution. As the recently
discovered class of supergiant fast X-ray transients (SFXT) seems to show the
same parameters for the wind, the link between persistent HMXB like Vela X-1
and SFXT is further strengthened.Comment: 8 pages, 6 figures, accepted for publication in A&
Neutrino Oscillations and the Supernova 1987A Signal
We study the impact of neutrino oscillations on the interpretation of the
supernova (SN) 1987A neutrino signal by means of a maximum-likelihood analysis.
We focus on oscillations between with or
with those mixing parameters that would solve the solar
neutrino problem. For the small-angle MSW solution (, ), there are no
significant oscillation effects on the Kelvin-Helmholtz cooling signal; we
confirm previous best-fit values for the neutron-star binding energy and
average spectral temperature. There is only marginal overlap
between the upper end of the 95.4\% CL inferred range of and the lower end of the range of theoretical
predictions. Any admixture of the stiffer spectrum by
oscillations aggravates the conflict between experimentally inferred and
theoretically predicted spectral properties. For mixing parameters in the
neighborhood of the large-angle MSW solution (, ) the oscillations in the SN are adiabatic,
but one needs to include the regeneration effect in the Earth which causes the
Kamiokande and IMB detectors to observe different spectra. For
the solar vacuum solution (,
) the oscillations in the SN are nonadiabatic; vacuum
oscillations take place between the SN and the detector. If either of the
large-angle solutions were borne out by the upcoming round of solar neutrino
experiments, one would have to conclude that the SN~1987A
and/or spectra had been much softer than predicted by currentComment: Final version with very minor wording changes, to be published in
Phys. Rev.
Direct Measurement of the Top Quark Mass at D0
We determine the top quark mass m_t using t-tbar pairs produced in the D0
detector by \sqrt{s} = 1.8 TeV p-pbar collisions in a 125 pb^-1 exposure at the
Fermilab Tevatron. We make a two constraint fit to m_t in t-tbar -> b W^+bbar
W^- final states with one W boson decaying to q-qbar and the other to e-nu or
mu-nu. Likelihood fits to the data yield m_t(l+jets) = 173.3 +- 5.6 (stat) +-
5.5 (syst) GeV/c^2. When this result is combined with an analysis of events in
which both W bosons decay into leptons, we obtain m_t = 172.1 +- 5.2 (stat) +-
4.9 (syst) GeV/c^2. An alternate analysis, using three constraint fits to fixed
top quark masses, gives m_t(l+jets) = 176.0 +- 7.9 (stat) +- 4.8 (syst)
GeV/C^2, consistent with the above result. Studies of kinematic distributions
of the top quark candidates are also presented.Comment: 43 pages, 53 figures, 33 tables. RevTeX. Submitted to Phys. Rev.
Present and Future CP Measurements
We review theoretical and experimental results on CP violation summarizing
the discussions in the working group on CP violation at the UK phenomenology
workshop 2000 in Durham.Comment: 104 pages, Latex, to appear in Journal of Physics
Two-photon widths of the states and helicity analysis for \chi_{c2}\ar\gamma\gamma}
Based on a data sample of 106 M events collected with the
BESIII detector, the decays \psi^{\prime}\ar\gamma\chi_{c0, 2},\chi_{c0,
2}\ar\gamma\gamma are studied to determine the two-photon widths of the
states. The two-photon decay branching fractions are determined
to be {\cal B}(\chi_{c0}\ar\gamma\gamma) = (2.24\pm 0.19\pm 0.12\pm
0.08)\times 10^{-4} and {\cal B}(\chi_{c2}\ar\gamma\gamma) = (3.21\pm 0.18\pm
0.17\pm 0.13)\times 10^{-4}. From these, the two-photon widths are determined
to be keV,
keV, and
, where the uncertainties
are statistical, systematic, and those from the PDG {\cal
B}(\psi^{\prime}\ar\gamma\chi_{c0,2}) and errors,
respectively. The ratio of the two-photon widths for helicity and
helicity components in the decay \chi_{c2}\ar\gamma\gamma is
measured for the first time to be .Comment: 10 pages, 4 figure
Higher-order multipole amplitude measurement in
Using events collected with the BESIII detector at
the BEPCII storage ring, the higher-order multipole amplitudes in the radiative
transition are measured.
A fit to the production and decay angular distributions yields
and , where the first
errors are statistical and the second systematic. Here denotes the
normalized magnetic quadrupole amplitude and the normalized electric
octupole amplitude. This measurement shows evidence for the existence of the
signal with statistical significance and is consistent with
the charm quark having no anomalous magnetic moment.Comment: 14 pages, 4 figure
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