23 research outputs found

    The distinct roles of spirituality and religiosity in physical and mental health after collective trauma: a national longitudinal study of responses to the 9/11 attacks

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    Researchers have identified health implications of religiosity and spirituality but have rarely addressed differences between these dimensions. The associations of religiosity and spirituality with physical and mental health were examined in a national sample (N = 890) after the September 11, 2001 terrorist attacks (9/11). Health information was collected before 9/11 and health, religiosity, and spirituality were assessed longitudinally during six waves of data collection over the next 3 years. Religiosity (i.e., participation in religious social structures) predicted higher positive affect (β = .12), fewer cognitive intrusions (β = -.07), and lower odds of new onset mental (incidence rate ratio [IRR] = .88) and musculoskeletal (IRR = .94) ailments. Spirituality (i.e., subjective commitment to spiritual or religious beliefs) predicted higher positive affect (β = .09), lower odds of new onset infectious ailments (IRR = 0.83), more intrusions (β = .10) and a more rapid decline in intrusions over time (β = -.10). Religiosity and spirituality independently predict health after a collective trauma, controlling for pre-event health status; they are not interchangeable indices of religion

    Design thinking for food well-Being. An adolescents’ language perspective

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    Design Thinking methodologies are often employed to create and generate solutions to a problem that specifically addresses the needs of consumers. In this chapter, we follow the first two steps of the DT process, problem definition and needs identification, to understand how adolescents frame and perceive concepts related to Food Well-Being. More specifically, in order to better assess the problem and to synthesize the needs, adolescents’ language is explored. Using a quantitative content analysis conducted with LIWC software, three trajectories of development of the Food Well-Being are identified. First, the role of school which is detrimental to the development of the social interaction needed for adolescents and their nutrition behavior; second, the importance of the idea of home in which adolescents seem to prefer consuming their meals and taking time for themselves; third the relevance of friends and peers in shaping both adolescents’ opinions and thoughts and their social processes

    The role of the immunoglobulin heavy chain in human anti‐dna antibody binding specificity

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    Objective. To investigate the structural basis for DNA binding of the natural human IgMλ monoclonal antibody KIM4.6. Methods. An IgMλ, non–DNA‐reactive variant hybridoma was derived during in vitro subcloning of the anti‐DNA antibody KIM4.6. The variable (V)‐region heavy (H) and light (L) chain genes expressed by the variant hybridoma were amplified by polymerase chain reaction, cloned, sequenced, and compared with those of the KIM4.6 parent and other DNA‐binding and non–DNA‐binding antibodies. Results. The VL chain of the variant was identical to that of KIM4.6. In contrast, the VH chain was completely different from the VH chain of the parent but was similar or identical, except in the diversity (D) and joining regions, to the VH chain of the systemic lupus erythematosus (SLE) IgG anti‐DNA antibody T14 and SLE IgM nephritogenic anti‐DNA antibodies NE‐1 and NE‐13. Conclusion. The expression of the KIM4.6 VL chain is not sufficient for DNA specificity. The VH chain and its D region play a key role in conferring DNA binding of the KIM4.6 anti‐DNA antibody. Copyright © 1995 American College of Rheumatolog
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