Concert recording 2018-02-24

[Track 1]. Etudes-caprices, op. 18. No. 1 Moderato - Allegro moderato - Tempo I [Track 2]. No. 2 Andante - Agitato e vigoroso - Motlo andante / Henri Wieniawski -- [Track 3]. Sonata for two violins, op. 56. I. Andante cantabile [Track 4]. II. Allegro [Track 5]. III. Commodo (quasi allegretto) [Track 6]. IV. Allegro con brio / Sergei Prokofiev -- [Track 7]. Duetti per due violini. 1. Béle [Track 8]. 3. Yossi [Track 9]. 5. Maja [Track 10]. 6. Bruno [Track 11]. 7. Camilla [Track 12]. 10. Giogio Federico [Track 13]. 11. Valerio [Track 14]. 18. Piero [Track 15]. 19. Annie [Track 16]. 20. Edoardo [Track 17]. 21. Flamma [Track 18]. 22. Vinko [Track 19]. 24. Aldo [Track 20]. 25. Carlo [Track 21]. 26. Henri [Track 22]. 27. Alfredo [Track 23]. 28. Igor [Track 24]. 29. Alfredo [Track 25]. 30. Massimo [Track 26]. 31. Mauricio [Track 27]. 32. Maurice [Track 28]. Lorin [Track 29]. 34. Lele / Luciano Berio -- [Track 30]. Sonata for two violins, op. 15. I. Allegro risoluto [Track 31]. II. Lento assai [Track 32]. III. Vivo e giocoso / Mikós Rozsa

The chemical polymerization of pyrryl Mannich base methiodide salt to porphyrins

Pyrryl Mannich base methiodides were polymerized in both anhydrous hydroxylic and nonhydroxylic solvents with the hope of clarifying some aspects of the mechanism of porphyrin formation. Although a mixture of type isomers were obtained, the product composition was found to consist of ~ 95% type (III and IV) and ~ 5% type (I and II) isomers from various solvents. The results suggested that the isomer composition is not dependent on the presence of “active” hydrogen in the solvent, and polymerization is not due to separation of formaldehyde (or equivalent) from the pyrrole and then a “random” polymerization; formation of type III and IV porphyrins is an inherent property of trimethylaminopyrrole salts and rearrangement in some form is a normal part of polymerization. On the basis of these results and published data, an intermediate with ring D porphobilinogen unit in the pyrrolenine form at right angles to the macrocycle formed from the other three pyrrole units and methane bridges is suggested and a scheme for the natural type III porphyrin formation is also proposed. -- A new compound diethyl 2,5-dimethyl-3,6-pyrazine-dithiolcarboxylate is reported as a by-product of a pyrryl thiolester synthesis

4,4′-Bipyridine–cyano­acetic acid (1/2)

Crystals of the title adduct, C10H8N2·2C3H3NO2, were obtained from a methanol/water solution of cyano­acetic acid and 4,4′-bipyridine at room temperature. In the crystal structure, cyano­acetic acid and centrosymmetric 4,4′-bipyridine mol­ecules are linked by O—H⋯N hydrogen bonds to form three-component supra­molecular adducts. The acidic H atom is almost midway between the O and N atoms of the cyano­acetic acid and bipyridine mol­ecules, with O—H and N—H distances of 1.19 (3) and 1.39 (3) Å, respectively, so that the H-atom transfer is best regarded as partial. The three-component adducts are further inter­connected with neighboring mol­ecules by weak inter­molecular C—H⋯O and C—H⋯N hydrogen bonds and by π–π stacking inter­actions [centroid–centroid distance = 3.7200 (11) Å] to generate a three-dimensional supra­molecular structure

Microstructure and Mechanical Properties of a-CN x Films Prepared by Bias Voltage Assisted PLD with Carbon Nitride Target

International audienceAmorphous carbon nitride (a-CN x) films were deposited on silicon substrates using pulsed laser deposition technique (PLD) with a carbon nitride target and a negative bias voltage up to -120 V. The microstructure, chemical composition, bonding configuration and mechanical properties of the films were characterized by using scanning electron microscopy (SEM), X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), Raman spectroscopy, nanoindentation and ball-on-disc abrasion test. The results show that the negative bias voltage promotes the formation of sp 3 hybridization bonding and leads to a great improvement of nitrogen content (up to 38 at.%) in the films. With an increasing bias voltage from -40 V to -120 V, the nitrogen content and the fraction of sp 3 hybridization bonding Corresponding author

Subtle mutations in the SMN1 gene in Chinese patients with SMA: p.Arg288Met mutation causing SMN1 transcript exclusion of exon7

BACKGROUND: Proximal spinal muscular atrophy (SMA) is a common neuromuscular disorder resulting in death during childhood. Around 81 ~ 95% of SMA cases are a result of homozygous deletions of survival motor neuron gene 1 (SMN1) gene or gene conversions from SMN1 to SMN2. Less than 5% of cases showed rare subtle mutations in SMN1. Our aim was to identify subtle mutations in Chinese SMA patients carrying a single SMN1 copy. METHODS: We examined 14 patients from 13 unrelated families. Multiplex ligation-dependent probe amplification analysis was carried out to determine the copy numbers of SMN1 and SMN2. Reverse transcription polymerase chain reaction (RT-PCR) and clone sequencing were used to detect subtle mutations in SMN1. SMN transcript levels were determined using quantitative RT-PCR. RESULTS: Six subtle mutations (p.Ser8LysfsX23, p.Glu134Lys, p.Leu228X, p.Ser230Leu, p.Tyr277Cys, and p.Arg288Met) were identified in 12 patients. The p.Tyr277Cys mutation has not been reported previously. The p.Ser8LysfsX23, p.Leu228X, and p.Tyr277Cys mutations have only been reported in Chinese SMA patients and the first two mutations seem to be the common ones. Levels of full length SMN1 (fl-SMN1) transcripts were very low in patients carrying p.Ser8LysfsX23, p.Leu228X or p.Arg288Met compared with healthy carriers. In patients carrying p.Glu134Lys or p.Ser230Leu, levels of fl-SMN1 transcripts were reduced but not significant. The SMN1 transcript almost skipped exon 7 entirely in patients with the p.Arg288Met mutation. CONCLUSIONS: Our study reveals a distinct spectrum of subtle mutations in SMN1 of Chinese SMA patients from that of other ethnicities. The p.Arg288Met missense mutation possibly influences the correct splicing of exon 7 in SMN1. Mutation analysis of the SMN1 gene in Chinese patients may contribute to the identification of potential ethnic differences and enrich the SMN1 subtle mutation database

Effects of electron beam radiation on trait mutation in azuki bean (Vigna angularisi)

Dry seeds of azuki bean (Vigna angularisi), Jingnong 6 and Hebei 801 varieties were irradiated by electron beam of 100, 300, 600, 700 and 900 Gy, respectively. Mutations of leaf shape and color, seed size and shape, trailing, more branching, dwarfing, early or late flowering time and high yield were created in M2 and M3 generations. There were richest variations in Jinnong 6 treated with 600 Gy. Heibei 801 was more sensitive to electron beam radiation than Jingnong 6; more mutation types were produced at 100, 300 and 600 Gy. The pod number per plant, seed number and yield per plant of Jinnong 6 displayed a strikingly negative correlation to radiation dose, while the pod length, pod width, and 100-seeds weight of progenies from Hebei 801 had a significantly negative correlation with the radiation dose, but pod number per plants showed significantly positive correlation. Few of the normal phenotype plant in M2 generation derived mutants of new leaf yellowing, narrow leaf, clustering flower and leaf, kidney or sword leaf in M3 generation. Mutants of kidney and sword leaf, early flowering time from M2 generation could be stably inherited in M3 generation.Keywords: Azuki bean (Vigna angularisi), electron beam radiation, trait mutatio

Discovering duplicate tasks in transition systems for the simplification of process models

This work presents a set of methods to improve the understandability of process models. Traditionally, simplification methods trade off quality metrics, such as fitness or precision. Conversely, the methods proposed in this paper produce simplified models while preserving or even increasing fidelity metrics. The first problem addressed in the paper is the discovery of duplicate tasks. A new method is proposed that avoids overfitting by working on the transition system generated by the log. The method is able to discover duplicate tasks even in the presence of concurrency and choice. The second problem is the structural simplification of the model by identifying optional and repetitive tasks. The tasks are substituted by annotated events that allow the removal of silent tasks and reduce the complexity of the model. An important feature of the methods proposed in this paper is that they are independent from the actual miner used for process discovery.Peer ReviewedPostprint (author's final draft

A thermodynamic unification of jamming

Fragile materials ranging from sand to fire-retardant to toothpaste are able to exhibit both solid and fluid-like properties across the jamming transition. Unlike ordinary fusion, systems of grains, foams and colloids jam and cease to flow under conditions that still remain unknown. Here we quantify jamming via a thermodynamic approach by accounting for the structural ageing and the shear-induced compressibility of dry sand. Specifically, the jamming threshold is defined using a non-thermal temperature that measures the 'fluffiness' of a granular mixture. The thermodynamic model, casted in terms of pressure, temperature and free-volume, also successfully predicts the entropic data of five molecular glasses. Notably, the predicted configurational entropy avoids the Kauzmann paradox entirely. Without any free parameters, the proposed equation-of-state also governs the mechanism of shear-banding and the associated features of shear-softening and thickness-invariance.Comment: 16 pgs double spaced. 4 figure