ANALISIS PENGARUH KONSUMEN DALAM KEPUTUSAN PEMBELIAN PRODUK PERALATAN RENANG MEREK ”SPEEDO” (Studi Kasus: Atlit Klub Renang di Seluruh Jateng)

Consumer’s decision is a decision t hat consumer’s make when they have to decide among two or more alternative choices. This also happened in competition among sports producer such as swim suit. SPEEDO is one of popular brand in the world. There are a lot of factor that influence buying decision in this SPEEDO brand, such as: quality, price and brand. With good quality, cheaper price, and popular brand, certainly SPEEDO will be much attract the consumers. So, the aim of this research were: (1) To examine influence of quality toward buying decision of pool equipment products SPEEDO. (2) To examine influence of price toward buying decision of pool equipment products SPEEDO. (3) To examine influence of brand toward buying decision of pool equipment products SPEEDO. This research measured by using regression analysis assist by SPSS. In collection data, this research analyzed primary data obtained from distributing questionnaire about 100 respondents, there were the customers of SPEEDO. Analysis result showed that : (1) There is positive and significant influence between quality toward buying decision of pool equipment products SPEEDO. (2) There is positive and significant influence between price toward buying decision of pool equipment products SPEEDO. (3) There is positive and significant influence between brand toward buying decision of pool equipment products SPEEDO

So Let Old Glory Wave

[Verse 1]We are marching on today for we are on our way,To help some brother, father friend,With our captain by our side,For America is our pride,And Liberty, and honor to the end. [Chorus]So let old Glory wave,We’ll all be strong and brave,No matter where we are, on land or sea,For we love our Stars and Stripes,They stand for freedom’s rights,And America, forever let it be. [Verse 2]So yes we’re marching on today for we find no other way,To hold old Glory up so true,And for Uncle Sam, we love, with our trust in God above,We’ll die if need, for the Red; White and Blue. [Chorus

Maine : I Sure Do Love You Best

https://digitalcommons.library.umaine.edu/mmb-me/1135/thumbnail.jp

Stability of XIST repression in relation to genomic imprinting following global genome demethylation in a human cell line

DNA methylation is essential in X chromosome inactivation and genomic imprinting, maintaining repression of XIST in the active X chromosome and monoallelic repression of imprinted genes. Disruption of the DNA methyltransferase genes DNMT1 and DNMT3B in the HCT116 cell line (DKO cells) leads to global DNA hypomethylation and biallelic expression of the imprinted gene IGF2 but does not lead to reactivation of XIST expression, suggesting that XIST repression is due to a more stable epigenetic mark than imprinting. To test this hypothesis, we induced acute hypomethylation in HCT116 cells by 5-aza-2′-deoxycytidine (5-aza-CdR) treatment (HCT116-5-aza-CdR) and compared that to DKO cells, evaluating DNA methylation by microarray and monitoring the expression of XIST and imprinted genes IGF2, H19, and PEG10. Whereas imprinted genes showed biallelic expression in HCT116-5-aza-CdR and DKO cells, the XIST locus was hypomethylated and weakly expressed only under acute hypomethylation conditions, indicating the importance of XIST repression in the active X to cell survival. Given that DNMT3A is the only active DNMT in DKO cells, it may be responsible for ensuring the repression of XIST in those cells. Taken together, our data suggest that XIST repression is more tightly controlled than genomic imprinting and, at least in part, is due to DNMT3A.FAPESP (#2008/07370-0

A framework for predicting X-nuclei transmitter gain using 1H signal

Commercial human MR scanners are optimised for proton imaging, containing sophisticated prescan algorithms with setting parameters such as RF transmit gain and power. These are not optimal for X-nuclear application and are challenging to apply to hyperpolarised experiments, where the non-renewable magnetisation signal changes during the experiment. We hypothesised that, despite the complex and inherently nonlinear electrodynamic physics underlying coil loading and spatial variation, simple linear regression would be sufficient to accurately predict X-nuclear transmit gain based on concomitantly acquired data from the proton body coil. We collected data across 156 scan visits at two sites as part of ongoing studies investigating sodium, hyperpolarised carbon, and hyperpolarised xenon. We demonstrate that simple linear regression is able to accurately predict sodium, carbon, or xenon transmit gain as a function of position and proton gain, with variation that is less than the intrasubject variability. In conclusion, sites running multinuclear studies may be able to remove the time-consuming need to separately acquire X-nuclear reference power calibration, inferring it from the proton instead

The maternal JAK/STAT pathway of Drosophila regulates embryonic dorsal-ventral patterning

Activation of NFkappaB plays a pivotal role in many cellular processes such as inflammation, proliferation and apoptosis. In Drosophila, nuclear translocation of the NFkappaB-related transcription factor Dorsal is spatially regulated in order to subdivide the embryo into three primary dorsal-ventral (DV) domains: the ventral presumptive mesoderm, the lateral neuroectoderm and the dorsal ectoderm. Ventral activation of the Toll receptor induces degradation of the IkappaB-related inhibitor Cactus, liberating Dorsal for nuclear translocation. In addition, other pathways have been suggested to regulate Dorsal. Signaling through the maternal BMP member Decapentaplegic (Dpp) inhibits Dorsal translocation along a pathway parallel to and independent of Toll. In the present study, we show for the first time that the maternal JAK/STAT pathway also regulates embryonic DV patterning. Null alleles of loci coding for elements of the JAK/STAT pathway, hopscotch (hop), marelle (mrl) and zimp (zimp), modify zygotic expression along the DV axis. Genetic analysis suggests that the JAK kinase Hop, most similar to vertebrate JAK2, may modify signals downstream of Dpp. In addition, an activated form of Hop results in increased levels of Cactus and Dorsal proteins, modifying the Dorsal/Cactus ratio and consequently DV patterning. These results indicate that different maternal signals mediated by the Toll, BMP and JAK/STAT pathways may converge to regulate NFkappaB activity in Drosophila