985 research outputs found

    Developing an Instrument to Assess the Effects of Pre-College Engineering Participation on the Experiences of First-Year Engineering Students

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    In this Complete Research paper, we describe the development of a survey instrument to measure the ways that students experience the transition from pre-college engineering activities to first-year engineering programs. As the number of opportunities to study and do engineering prior to matriculation in an undergraduate engineering program increases, first-year engineering students draw from a diverse range of pre-college engineering experiences that affect their transition to studying engineering at a university. The instrument utilizes a theoretical framework developed via a phenomenographic interview process that identified five distinct ways students experience the transition from pre-college to university engineering. These range from foreclosure or a feeling of entrapment in engineering, to frustration, to tedium, to connection, to the ability to help others be successful in first-year engineering. Utilizing the interview data that informed the development of these categories, we identified statements associated with each of these ways of experiencing the transition from pre-college to university engineering and used these statements to develop an initial instrument consisting of 65 Likert-type questions on students’ experiences combined with detailed questions on both the types pre-college engineering experiences the students participated in and the content of these experiences. Validation of the initial instrument involved multiple rounds of feedback from experts in both pre-college and first-year engineering education, followed by an initial administration of the instrument to the first-year student population at two universities. Analysis of these results showed that overall the instrument had good reliability, however we identified 15 low functioning items for removal, reducing the total number of items to 50. Upon completion of the development process, we administered the final instrument again to another population of first-year engineering students. Analysis of these results using Exploratory Factor Analysis yields components that align well with most elements of the aforementioned theoretical framework. However, we identified several additional independent factors related to ways that students experience disconnects or frustration when transitioning from pre-college to first-year engineering programs. Pre-college engineering is growing, but students arrive in first-year engineering programs with varying levels of prior exposure to engineering. Understanding how pre-college experiences affect students’ transitions to engineering will provide valuable data for both the creators and instructors of pre-college and first-year engineering curricula, and facilitate better alignment between these interrelated spheres of engineering education

    Widespread mRNA Association with Cytoskeletal Motor Proteins and Identification and Dynamics of Myosin-Associated mRNAs in S. cerevisiae

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    Programmed mRNA localization to specific subcellular compartments for localized translation is a fundamental mechanism of post-transcriptional regulation that affects many, and possibly all, mRNAs in eukaryotes. We describe her e a systematic approach to identify the RNA cargoes associated with the cytoskeletal motor proteins of Saccharomyces cerevisiae in combination with live-cell 3D super-localization microscopy of endogenously tagged mRNAs. Our analysis identified widespread association of mRNAs with cytoskeletal motor proteins, including association of Myo3 with mRNAs encoding key regulators of actin branching and endocytosis such as WASP and WIP. Using conventional fluorescence microscopy and expression of MS2-tagged mRNAs from endogenous loci, we observed a strong bias for actin patch nucleator mRNAs to localize to the cell cortex and the actin patch in a Myo3- and F-actin dependent manner. Use of a double-helix point spread function (DH-PSF) microscope allowed super-localization measurements of single mRNPs at a spatial precision of 25 nm in x and y and 50 nm in z in live cells with 50 ms exposure times, allowing quantitative profiling of mRNP dynamics. The actin patch mRNA exhibited distinct and characteristic diffusion coefficients when compared to a control mRNA. In addition, disruption of F-actin significantly expanded the 3D confinement radius of an actin patch nucleator mRNA, providing a quantitative assessment of the contribution of the actin cytoskeleton to mRNP dynamic localization. Our results provide evidence for specific association of mRNAs with cytoskeletal motor proteins in yeast, suggest that different mRNPs have distinct and characteristic dynamics, and lend insight into the mechanism of actin patch nucleator mRNA localization to actin patches

    Convergence of the Magnus series

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    The Magnus series is an infinite series which arises in the study of linear ordinary differential equations. If the series converges, then the matrix exponential of the sum equals the fundamental solution of the differential equation. The question considered in this paper is: When does the series converge? The main result establishes a sufficient condition for convergence, which improves on several earlier results.Comment: 11 pages; v2: added justification for conjecture, minor clarifications and correction

    Causal propagation of geometrical fields in relativistic cosmology

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    We employ the extended 1+3 orthonormal frame formalism for fluid spacetime geometries (M,g,u)({\cal M}, {\bf g}, {\bf u}), which contains the Bianchi field equations for the Weyl curvature, to derive a 44-D evolution system of first-order symmetric hyperbolic form for a set of geometrically defined dynamical field variables. Describing the matter source fields phenomenologically in terms of a barotropic perfect fluid, the propagation velocities vv (with respect to matter-comoving observers that Fermi-propagate their spatial reference frames) of disturbances in the matter and the gravitational field, represented as wavefronts by the characteristic 3-surfaces of the system, are obtained. In particular, the Weyl curvature is found to account for two (non-Lorentz-invariant) Coulomb-like characteristic eigenfields propagating with v=0v = 0 and four transverse characteristic eigenfields propagating with v=1|v| = 1, which are well known, and four (non-Lorentz-invariant) longitudinal characteristic eigenfields propagating with |v| = \sfrac{1}{2}. The implications of this result are discussed in some detail and a parallel is drawn to the propagation of irregularities in the matter distribution. In a worked example, we specialise the equations to cosmological models in locally rotationally symmetric class II and include the constraints into the set of causally propagating dynamical variables.Comment: 25 pages, RevTeX (10pt), accepted for publication by Physical Review

    Limits on Gravitational-Wave Emission from Selected Pulsars Using LIGO Data

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    We place direct upper limits on the amplitude of gravitational waves from 28 isolated radio pulsars by a coherent multidetector analysis of the data collected during the second science run of the LIGO interferometric detectors. These are the first direct upper limits for 26 of the 28 pulsars. We use coordinated radio observations for the first time to build radio-guided phase templates for the expected gravitational-wave signals. The unprecedented sensitivity of the detectors allows us to set strain upper limits as low as a few times 10^(-24). These strain limits translate into limits on the equatorial ellipticities of the pulsars, which are smaller than 10^(-5) for the four closest pulsars

    Reactive direction control for a mobile robot: A locust-like control of escape direction emerges when a bilateral pair of model locust visual neurons are integrated

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    Locusts possess a bilateral pair of uniquely identifiable visual neurons that respond vigorously to the image of an approaching object. These neurons are called the lobula giant movement detectors (LGMDs). The locust LGMDs have been extensively studied and this has lead to the development of an LGMD model for use as an artificial collision detector in robotic applications. To date, robots have been equipped with only a single, central artificial LGMD sensor, and this triggers a non-directional stop or rotation when a potentially colliding object is detected. Clearly, for a robot to behave autonomously, it must react differently to stimuli approaching from different directions. In this study, we implement a bilateral pair of LGMD models in Khepera robots equipped with normal and panoramic cameras. We integrate the responses of these LGMD models using methodologies inspired by research on escape direction control in cockroaches. Using ‘randomised winner-take-all’ or ‘steering wheel’ algorithms for LGMD model integration, the khepera robots could escape an approaching threat in real time and with a similar distribution of escape directions as real locusts. We also found that by optimising these algorithms, we could use them to integrate the left and right DCMD responses of real jumping locusts offline and reproduce the actual escape directions that the locusts took in a particular trial. Our results significantly advance the development of an artificial collision detection and evasion system based on the locust LGMD by allowing it reactive control over robot behaviour. The success of this approach may also indicate some important areas to be pursued in future biological research

    Searching for gravitational waves from known pulsars

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    We present upper limits on the amplitude of gravitational waves from 28 isolated pulsars using data from the second science run of LIGO. The results are also expressed as a constraint on the pulsars' equatorial ellipticities. We discuss a new way of presenting such ellipticity upper limits that takes account of the uncertainties of the pulsar moment of inertia. We also extend our previous method to search for known pulsars in binary systems, of which there are about 80 in the sensitive frequency range of LIGO and GEO 600.Comment: Accepted by CQG for the proceeding of GWDAW9, 7 pages, 2 figure

    Upper limits on the strength of periodic gravitational waves from PSR J1939+2134

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    The first science run of the LIGO and GEO gravitational wave detectors presented the opportunity to test methods of searching for gravitational waves from known pulsars. Here we present new direct upper limits on the strength of waves from the pulsar PSR J1939+2134 using two independent analysis methods, one in the frequency domain using frequentist statistics and one in the time domain using Bayesian inference. Both methods show that the strain amplitude at Earth from this pulsar is less than a few times 102210^{-22}.Comment: 7 pages, 1 figure, to appear in the Proceedings of the 5th Edoardo Amaldi Conference on Gravitational Waves, Tirrenia, Pisa, Italy, 6-11 July 200

    Improving the sensitivity to gravitational-wave sources by modifying the input-output optics of advanced interferometers

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    We study frequency dependent (FD) input-output schemes for signal-recycling interferometers, the baseline design of Advanced LIGO and the current configuration of GEO 600. Complementary to a recent proposal by Harms et al. to use FD input squeezing and ordinary homodyne detection, we explore a scheme which uses ordinary squeezed vacuum, but FD readout. Both schemes, which are sub-optimal among all possible input-output schemes, provide a global noise suppression by the power squeeze factor, while being realizable by using detuned Fabry-Perot cavities as input/output filters. At high frequencies, the two schemes are shown to be equivalent, while at low frequencies our scheme gives better performance than that of Harms et al., and is nearly fully optimal. We then study the sensitivity improvement achievable by these schemes in Advanced LIGO era (with 30-m filter cavities and current estimates of filter-mirror losses and thermal noise), for neutron star binary inspirals, and for narrowband GW sources such as low-mass X-ray binaries and known radio pulsars. Optical losses are shown to be a major obstacle for the actual implementation of these techniques in Advanced LIGO. On time scales of third-generation interferometers, like EURO/LIGO-III (~2012), with kilometer-scale filter cavities, a signal-recycling interferometer with the FD readout scheme explored in this paper can have performances comparable to existing proposals. [abridged]Comment: Figs. 9 and 12 corrected; Appendix added for narrowband data analysi
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