543 research outputs found

    A Linguistic Recommender System For University Digital Libraries To Help Users In Their Research Resources Accesses

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    The Web is one of the most important information media and it is influencing in the development of other media, as for example, newspapers, journals, books, libraries, etc. Moreover, in recent days people want to communicate and collaborate. So, libraries must develop services for connecting people together in information environments. Then, the library staff needs automatic techniques to facilitate that a great number of users can access to a great number of resources. Recommender systems are tools whose objective is to evaluate and filter the great amount of information available on the Web. We present a model of a fuzzy linguistic recommender system to help University Digital Library users in their research resources accesses. This system recommends researchers specialized and complementary resources in order to discover collaboration possibilities to form multi-disciplinaryy groups. In this way, this system increases social collaboration possibilities in a university framework and contributes to improve the services provided by a University Digital Library

    EFECTOS ECONÓMICO DE LA CRISIS FINANCIERA INTERNACIONAL 2007 EN PANAMÁ.

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    We present the transmission channels, in Latina America and the Caribbean, of the international financial crisis, generated in the United States, followed by approach of its effects and the macroeconomic impact on engines development of the Republic of Panama, basic for economic and financial analysis of the country.Se consideran para América Latina y El Caribe los canales de transmisión de la Crisis Financiera Internacional generada en los EUA, se sintetizan sus efectos y las políticas económicas adoptadas así como también: los acuerdos globales de los macro organismos internacionales. Efectos y medidas regionales que se focalizan en el impacto económico que genera la misma en los motores del desarrollo de la República de Panamá, información fundamental para los análisis económicos y financieros del país

    Smoke and fire dynamics in atria and large enclosures: An overview

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    The proliferation of atria within modern large buildings is relatively recent. An atrium can be defined as a large open space connecting two or more storeys. Atria are important architectonical features since the 60's and can be found, among others, in shopping centres, office buildings and high-rise buildings, airports, stations and sports centres. However, the atrium represents an innovative, complex and non conventional architectonical element that can lead to fire environments diverging significantly from those in conventional compartments used in the development of current codes and standards. They are a source of discussion in the fire safety community because smoke can easily spread from one floor to another making the traditional methodologies for compartmentation of little or null effect. The design of smoke management in atria has been based on prescriptive codes since the 70's. It was not until the mid 80's that the phenomena started to be the objective of both experimental and numerical studies. It is because of the subsequent improved understanding on fire dynamics and smoke management together with the increased computing power available nowadays, that there is a progressive movement from prescriptive-based to performance-based codes which is also chaning the way atria are designed. The aim of the present work is to provide a broad overview of the current state-of-the-art of fires in atria. A brief introduction to the characteristics and types of atrium structures is presented first. Then, a description of the fire dynamics as well as the main safety problems that arise in case of fire are considered. A historical discussion of the research, including experimental and numerical studies, is presented, and current design methodologies and fire safety strategies are discussed. The final part of the overview addresses the international tendencies towards the introduction of performance-based fire protection codes. This overview highlights the need for further experimental studies and validations of numerical simulations for a wider range of fire conditions. © 2010 by Nova Science Publishers, Inc. All rights reserved

    Machine learning methods for systemic risk analysis in financial sectors.

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    Financial systemic risk is an important issue in economics and financial systems. Trying to detect and respond to systemic risk with growing amounts of data produced in financial markets and systems, a lot of researchers have increasingly employed machine learning methods. Machine learning methods study the mechanisms of outbreak and contagion of systemic risk in the financial network and improve the current regulation of the financial market and industry. In this paper, we survey existing researches and methodologies on assessment and measurement of financial systemic risk combined with machine learning technologies, including big data analysis, network analysis and sentiment analysis, etc. In addition, we identify future challenges, and suggest further research topics. The main purpose of this paper is to introduce current researches on financial systemic risk with machine learning methods and to propose directions for future work.This research has been partially supported by grants from the National Natural Science Foundation of China (#U1811462, #71874023, #71771037, #71725001, and #71433001)

    Robust self-replication of combinatorial information via crystal growth and scission

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    Understanding how a simple chemical system can accurately replicate combinatorial information, such as a sequence, is an important question for both the study of life in the universe and for the development of evolutionary molecular design techniques. During biological sequence replication, a nucleic acid polymer serves as a template for the enzyme-catalyzed assembly of a complementary sequence. Enzymes then separate the template and complement before the next round of replication. Attempts to understand how replication could occur more simply, such as without enzymes, have largely focused on developing minimal versions of this replication process. Here we describe how a different mechanism, crystal growth and scission, can accurately replicate chemical sequences without enzymes. Crystal growth propagates a sequence of bits while mechanically-induced scission creates new growth fronts. Together, these processes exponentially increase the number of crystal sequences. In the system we describe, sequences are arrangements of DNA tile monomers within ribbon-shaped crystals. 99.98% of bits are copied correctly and 78% of 4-bit sequences are correct after two generations; roughly 40 sequence copies are made per growth front per generation. In principle, this process is accurate enough for 1,000-fold replication of 4-bit sequences with 50% yield, replication of longer sequences, and Darwinian evolution. We thus demonstrate that neither enzymes nor covalent bond formation are required for robust chemical sequence replication. The form of the replicated information is also compatible with the replication and evolution of a wide class of materials with precise nanoscale geometry such as plasmonic nanostructures or heterogeneous protein assemblies

    Revealing hidden clonal complexity in Mycobacterium tuberculosis infection by qualitative and quantitative improvement of sampling

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    AbstractThe analysis of microevolution events, its functional relevance and impact on molecular epidemiology strategies, constitutes one of the most challenging aspects of the study of clonal complexity in infection by Mycobacterium tuberculosis. In this study, we retrospectively evaluated whether two improved sampling schemes could provide access to the clonal complexity that is undetected by the current standards (analysis of one isolate from one sputum). We evaluated in 48 patients the analysis by mycobacterial interspersed repetitive unit–variable number tandem repeat of M. tuberculosis isolates cultured from bronchial aspirate (BAS) or bronchoalveolar lavage (BAL) and, in another 16 cases, the analysis of a higher number of isolates from independent sputum samples. Analysis of the isolates from BAS/BAL specimens revealed clonal complexity in a very high proportion of cases (5/48); in most of these cases, complexity was not detected when the isolates from sputum samples were analysed. Systematic analysis of isolates from multiple sputum samples also improved the detection of clonal complexity. We found coexisting clonal variants in two of 16 cases that would have gone undetected in the analysis of the isolate from a single sputum specimen. Our results suggest that analysis of isolates from BAS/BAL specimens is highly efficient for recording the true clonal composition of M. tuberculosis in the lungs. When these samples are not available, we recommend increasing the number of isolates from independent sputum specimens, because they might not harbour the same pool of bacteria. Our data suggest that the degree of clonal complexity in tuberculosis has been underestimated because of the deficiencies inherent in a simplified procedure

    Evaluation of bone marrow and blood cultures for the recovery of mycobacteria in the diagnosis of disseminated mycobacterial infections

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    AbstractThis study evaluated the validity of bone marrow (BM) and blood specimens for the diagnosis of disseminated mycobacterial infections (DMIs). From 1990 to February 1997, all specimens were processed with the lysis-centrifugation procedure; thereafter (until December 2001), they were processed with the BACTEC Myco/F Lytic system. Twenty-three paired BM-blood specimens with mycobacteria in at least one specimen were studied from 23 patients. The strains isolated were 14 Mycobacterium avium complex (MAC) and nine M. tuberculosis complex (MTBC). Blood specimens had a statistically significant greater sensitivity for the isolation of MAC than BM (100% vs. 57.1%, respectively), whereas sensitivity for the isolation of MTBC was equal for the two specimen types (66.7%). Although not statistically significant, the times required to detect mycobacteria from blood specimens were lower than those from BM in the MycoF/Lytic system. Overall, blood cultures represented a more sensitive and less invasive alternative to BM cultures for the diagnosis of disseminated mycobacteriosis caused by MAC, especially when the MycoF/Lytic system was used, but provided no advantage for the diagnosis of DMI caused by MTBC
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