3,233 research outputs found

    Simulating budget system in the agent model of the Russian Federation spatial development

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    In this paper we present methods, data and algorithms for simulating budget system in the model of the Russian Federation spatial development. We show the place of this task in methodology of our research and give a brief overview of the background results. We determine revenues and expenditures of the budgets and funds on the basis of federal laws, Budget and Tax codes of the Russian Federation. For validation of the budget system algorithms in the model we conduct retrospective modeling for the federal budget and the budget of Belgorod region in 201

    Triple molybdates one-, one - and three(two)valence metals

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    The authors thank Ph. D. M. K. Alibaeva, Ph. D. I. A. Gudkova and Ph. D. I. V. Korolkova for participation in the research.The review summarizes experimental data on the phase formation, structure and properties of new complex oxide compounds group - triple molybdates containing tetrahedral molybdate ion, two different singly charged cation, together with tri- or divalent cation. The several structural families of these compounds were distinguished and it shown that many of them are of interest as luminescent, laser, ion-conducting or nonlinear optical materials.The work is executed at partial support of the Russian Foundation for basic research (projects No. 08-03-00384, 13-03-01020 and 14-03-00298)

    Rendu-Osler-Weber Disease with High Pulmonary Hypertension and Interstitial Lung Disease

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    A 64-year-old female with a family history of hereditary hemorrhagic telangiectasia (HHT) was hospitalized due to complaints of dyspnea during light physical exertion and leg edema. HHT was diagnosed at 20 y.o., recurrent nasal bleeding started at age 52, bleedings severity was aggravated by not completely compensated hypertension. At the age of 60, after a massive hemorrhage, she noted the onset of dyspnea, edema, ascites. Diuretics and iron preparations improved her well-being, but from that period onward her heart failure worsened after each massive blood loss. The last major bleeding was before the present hospitalization (Hgb 67 g/l), after which heart failure symptoms significantly deteriorated. Echocardiography showed preserved left ventricular ejection fraction, but revealed high pulmonary hypertension (systolic pulmonary artery pressure 69 mmHg). Chest computed tomography (CT) with contrast showed no evidence of pulmonary embolism, but interstitial lung lesions were detected. Pulse therapy with glucocorticosteroids did not result in positive dynamics at the control CT scan, which allowed to reject a separate interstitial lung disease. As a result of cardiotropic and diuretic therapy, as well as correction of anemia, the patient's condition improved. Macitentan was administered, but the patient refused from it because one of possible side effects was anemia. A year later the patient diedfrom acute progression of pulmonary hypertension. According to the literature, pulmonary hypertension in HHT can have a significant impact on the prognosis and requires timely diagnosis and treatment. Interstitial lung lesions are a manifestation of the underlying disease and does not require special treatment

    Magnetic properties of the antiferromagnetic spin-1/2 chain system β\beta-TeVO4_{4}

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    The magnetic susceptibility and magnetization of high quality single crystal beta-TeVO4 are reported. We show that this compound, made of weakly coupled infinite chains of VO5 pyramids sharing corners, behaves as a S = 1/2 one-dimensional Heisenberg antiferromagnet. From magnetic experiments we deduce the intrachain antiferromagnetic coupling constant J/kB = 21.4 ±\pm 0.2 K. Below 5 K a series of three phase transitions at 2.26, 3.28 and 4.65 K is observed.Comment: Accepted for publication in Physical Review

    Information Technologies for Assessing the Quality of IT-specialties Graduates' Training of University by Means of Fuzzy Logic and Neural Networks

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    The information technologies for assessing the quality of IT-specialties graduates' training of university by means of fuzzy logic and neural networks are developed in the article. It makes possible taking into account a wide set of estimation and output parameters, influence of the external and internal factors and allows to simplify the assessing process by means of modern mathematical apparatuses of artificial intelligence

    The Impact of the COVID-19 Pandemic on Natural Population Movement in the Ural Federal District

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    COVID-19 pandemic led to high levels of excess mortality nearly in all world regions. Since the second quarter of 2020, mortality rates are increasing. The widespread of coronavirus infection worsened the situation with natural population decrease in the Ural Federal District. Natural growth, despite its certain reduction, was maintained only in Khanty-Mansi and Yamal-Nenets Autonomous okrugs. In most regions of the Ural Federal District in 2020-2021, there was a slight decrease in fertility rates. However, the situation with mortality in the district developed more sharply; increase in crude mortality was 34.2 % up to 15.7 ‰. The highest mortality growth was recorded in Khanty-Mansi autonomous okrug (+41.7 %), while natural population growth has remained. The most dramatic situation persists in Kurgan oblast, where crude mortality rate in 2021 was 20.4 %. Determining shares of deaths from COVID-19 in additional losses in 2020 and 2021 compared to 2019 indicates a violation of the coding rules when choosing the primary cause of death, which does not allow to assess the true picture of the causes of death in the Ural Federal District.Пандемия COVID-19 привела к высоким уровням избыточной смертности практически во всех регионах страны. Со второго квартала 2020 г. показатели смертности демонстрируют рост. Распространение коронавирусной инфекции усугубило ситуацию с естественной убылью населения в УрФО. Естественный прирост, несмотря не некоторое его снижение, сохранился лишь в ХМАО и ЯНАО. В большинстве регионов УрФО в 2020-2021 гг. произошло некоторое снижение показателей рождаемости. Но ситуация со смертностью населения в округе развивалась более драматично, рост общей смертности составил 34,2 %, достигнув 15,7 ‰. Наибольший прирост смертности отмечен в ХМАО (41,7 %), тем не менее, в регионе сохранился естественный прирост населения. Самая драматичная ситуация сохраняется в Курганской области, где в 2021 г. показатель смертности составил 20,4 ‰. Определение доли умерших от COVID-19 в дополнительных потерях в 2020 и 2021 гг. по сравнению с 2019 г. указывает на нарушение правил кодирования при выборе первоначальной причины смерти, что не позволяет оценить истинную картину причин смерти в УрФО

    Systems biology analysis of the WOX5 gene and its functions in the root stem cell niche

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    WUSCHEL RELATED HOMEOBOX 5 (WOX5) gene encodes the transcription factor, which is one of the key regulators, maintaining structure and functioning of the stem cell niche in plant root tips. Protein WOX5 is expressed in the quiescent center of the root apical meristem, preventing differentiation of columella initials and altogether with SCR, SHR, PLT1 and PLT2 participating in the control of differentiation of other root meristem initials. However, the details of WOX5 functioning are unclear. The WOX5 protein belongs to WUSCHEL related homeobox (WOX) family, the founder of which is the transcription factor WUSCHEL (WUS) providing maintenance of the stem cell niche in the shoot apical meristem. WOX5 and WUS diverged from a common ancestor at the base of angiosperms, which resulted in a specialization of shoot and root stem cell niches. However, the problem of WOX5 structural and functional divergence during angiosperm evolution was poorly addressed. In this review we present a systems biology analysis of the WOX5 gene to reveal specific features of its evolution and functioning. To this end, we performed a phylogenetic analysis on 62 publicly available WOX5 amino acid sequences, generalized published data about WOX5 expression domain in Arabidopsis and other species and its role in development, integrated the results of experiments on identification of primary and secondary targets for this transcription factor. Data on possible mechanisms of direct and indirect regulation of WOX5 expression were discussed. Particularly, we performed the analysis of WOX5 promoter regions from 30 species. Possible direct regulators of the WOX5 gene expression were proposed based on the presence of putative binding sites for the candidate transcription factors in conserved WOX5 promoter regions

    Russian Higher School: Forced Distance Learning and Planned Switch to Distance Learning During Pandemic (Experience of Sociological Analysis)

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    Challenges related to the COVID-19 pandemic require structural analysis and sociocultural comprehension, which has and will for quite a while have multi-aspect and systemic nature. All elements of the social system have been forced to function in the stress regime in the absence of any basic patterns and tried-and-true methods to solve the arising problem. The overall uncertainty in the organization of the social life and the enforced and, at times, very contentious steps taken at various levels of management have caused polarization of opinions as to the functioning of all social institutions. Special pressure has been put on education, since it is this  institution that is mainly responsible for the social system’s stability. In this regard, it has been important and significant to comprehensively  study the problems and limitations associated with the functioning of the  higher education system in Russia during the pandemic, as well as to analyze the change in tone and attitude both on the part of the public and the teaching corps, as a response to the transition to the new forms of work at higher education institutions.The article was prepared using the materials of two stages of the  sociological research “The opinion of teachers of Russia’s higher education  institutions on distance learning during the pandemic” conducted in May, June and December 2020. The volume of sample sets made up 3431 people at the first stage, and 6006, at the second. An analysis of research data covers the following areas: organizational problems of transition to distance  learning; resources used, organization of lectures and seminars, assessment  of the positive and negative aspects of distance learning; perspectives,  limitations and trajectories for the implementation of distance learning in Russia’s higher education institutions, as well as a set of social problems aimed at studying social well-being and assessing possible changes in the life and career of teachers.The research data are compared with the data of similar works by Russian and foreign analysts. On the basis of the analysis done and the conclusions obtained, the authors propose practical steps to optimize the work of the higher education system in stressful situations, to use distance technologies in the learning organization. Also, possible forms are considered that  combine distance and full-time education, and recommendations are proposed on how to change the tone in perceiving inevitable informational and communication transformations on the part of teachers.This research was performed according to the Development program of the  Interdisciplinary Scientific and Educational School of Lomonosov Moscow  State University «Mathematical methods of complex systems analysis»

    Crystal and Electronic Structures of Alluaudite-Type Double Molybdates of Scandium and Indium

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    Double molybdates of indium and scandium with alluaudite structure are prepared by the solid-phase synthesis method. The crystal structure of the indium containing compound is refined and optical characteristics of Na5R(Mo04)4(R = Sc, In) are determined. Electronic structures of Na5R(Mo04)4(R = Sc, In) molybdates are studied within the ab initio method taking account of Na/Sc(In) positional disordering. Calculations of the imaginary part of dielectric function predict the optical gap of ~3.8 eV, in accordance with absorption spectroscopy data. It is established that formation energy of sodium vacancies strongly depends on sodium position and Sc(In) concentration. As a result, various diffusion mechanisms may be activated in alluaudite-type compounds with high and low contents of metal R. © 2019, Pleiades Publishing, Ltd
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